Biological and Molecular Efficiency of Paracentrotus lividus Shell in vitro Study: Antioxidant and Angiogenesis Effects Against T47D Breast Cancer Cell Line Via Nrf2/HMOX-1/ and HIF-1α /VEGF Signaling Pathways

Blackadar, C. B. (2016). Historical review of the causes of cancer. World Journal of Clinical Oncology, 7, 54.

Article  PubMed  PubMed Central  Google Scholar 

Karağaç, M. S., Yeşilkent, E. N., Kizir, D., Öztürk, N., Isıyel, M., Karadaş, H., Tosun, H., Karaman, M., Ceylan, H., & Demir, Y. (2024). Esculetin improves inflammation of the kidney via gene expression against doxorubicin-induced nephrotoxicity in rats: In vivo and in silico studies. Food Bioscience, 62, 105159.

Article  Google Scholar 

Kensler, T. W., Wakabayashi, N., & Biswal, S. (2007). Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annual Review of Pharmacology and Toxicology, 47, 89–116.

Article  CAS  PubMed  Google Scholar 

Kizir, D., Yeşilkent, E. N., Öztürk, N., Karağaç, M. S., Isıyel, M., Tosun, H., Karadaş, H., Ceylan, H., Karaman, M., & Demir, Y. (2024). The protective effects of esculetin against doxorubicin‐induced hepatotoxicity in rats: Insights into the modulation of Caspase, FOXOs, and heat shock protein pathways. Journal of Biochemical and Molecular Toxicology, 38, e23861.

Article  CAS  PubMed  Google Scholar 

Hämäläinen, R. H., Ahlqvist, K. J., Ellonen, P., Lepistö, M., Logan, A., Otonkoski, T., Murphy, M. P., & Suomalainen, A. (2015). mtDNA mutagenesis disrupts pluripotent stem cell function by altering redox signaling. Cell Reports, 11, 1614–1624.

Article  PubMed  Google Scholar 

Demir, Y. (2020). Naphthoquinones, benzoquinones, and anthraquinones: Molecular docking, ADME and inhibition studies on human serum paraoxonase‐1 associated with cardiovascular diseases. Drug Development Research, 81, 628–636.

Article  CAS  PubMed  Google Scholar 

Demir, Y. (2019). The behaviour of some antihypertension drugs on human serum paraoxonase-1: an important protector enzyme against atherosclerosis. Journal of Pharmacy and Pharmacology, 71, 1576–1583.

Article  CAS  PubMed  Google Scholar 

Özturk, N., Ceylan, H., & Demir, Y. (2024). The hepatoprotective potential of tannic acid against doxorubicin‐induced hepatotoxicity: insights into its antioxidative, anti‐inflammatory, and antiapoptotic mechanisms. Journal of Biochemical and Molecular Toxicology, 38, e23798.

Article  PubMed  Google Scholar 

Köroğlu, Z., Kizir, D., Karaman, M., Demir, Y., Türkeş, C., & Beydemir, Ş. (2024). Protective effects of esculetin against doxorubicin‐induced toxicity correlated with oxidative stress in rat liver: In vivo and in silico studies. Journal of Biochemical and Molecular Toxicology, 38, e23702.

Article  PubMed  Google Scholar 

Lü, J.-M., Jiang, J., Jamaluddin, M. S., Liang, Z., Yao, Q., & Chen, C. (2019). Ginsenoside Rb1 blocks ritonavir-induced oxidative stress and eNOS downregulation through activation of estrogen receptor-beta and upregulation of SOD in human endothelial cells. International Journal of Molecular Sciences, 20, 294.

Article  PubMed  PubMed Central  Google Scholar 

Sulumer, A. N., Palabıyık, E., Avcı, B., Uguz, H., Demir, Y., Serhat Özaslan, M., & Aşkın, H. (2024). Protective effect of bromelain on some metabolic enzyme activities in tyloxapol‐induced hyperlipidemic rats. Biotechnology and Applied Biochemistry, 71, 17–27.

Article  CAS  PubMed  Google Scholar 

Xu, L., Yang, J., Xu, M., Shan, D., Wu, Z., & Yuan, D. (2020). Speciation and adaptive evolution reshape antioxidant enzymatic system diversity across the phylum Nematoda. BMC Biology, 18, 1–18.

Article  CAS  Google Scholar 

Öztürk, N., Karağaç, M. S., Yeşilkent, E. N., Isıyel, M., Tosun, H., Karadaş, H., Ceylan, H., & Demir, Y. (2024). Exploring Esculetin’s protective role: Countering doxorubicin-induced oxidative stress in rat heart. Laboratuvar Hayvanları Bilimi ve Uygulamaları Dergisi, 4, 44–52.

Google Scholar 

Demir, Y., Öztürk, N., Isıyel, M., & Ceylan, H. (2024). Effects of carnosic and usnic acid on pentose phosphate pathway enzymes: an experimental and molecular docking study. ChemistrySelect, 9, e202401067.

Article  CAS  Google Scholar 

Mukaigasa, K., Nguyen, L. T., Li, L., Nakajima, H., Yamamoto, M., & Kobayashi, M. (2012). Genetic evidence of an evolutionarily conserved role for Nrf2 in the protection against oxidative stress. Molecular and Cellular Biology, 32, 4455–4461.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kang, K. A., Lee, K. H., Park, J. W., Lee, N. H., Na, H. K., Surh, Y. J., You, H. J., Chung, M. H., & Hyun, J. W. (2007). Triphlorethol-A induces heme oxygenase-1 via activation of ERK and NF-E2 related factor 2 transcription factor. FEBS Letters, 581, 2000–2008.

Article  CAS  PubMed  Google Scholar 

Loboda, A., Damulewicz, M., Pyza, E., Jozkowicz, A., & Dulak, J. (2016). Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism. Cellular and Molecular Life Sciences, 73, 3221–3247.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zimna, A., & Kurpisz, M. (2015). Hypoxia-inducible factor-1 in physiological and pathophysiological angiogenesis: applications and therapies. BioMed Research International, 2015, 549412.

Article  PubMed  PubMed Central  Google Scholar 

Palmer, B. F., & Clegg, D. J. (2014). Oxygen sensing and metabolic homeostasis. Molecular and Cellular Endocrinology, 397, 51–58.

Article  CAS  PubMed  Google Scholar 

Shibuya, M. (2011). Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) signaling in angiogenesis: a crucial target for anti-and pro-angiogenic therapies. Genes & Cancer, 2, 1097–1105.

Article  Google Scholar 

Jin, F., Zheng, X., Yang, Y., Yao, G., Ye, L., Doeppner, T. R., Hermann, D. M., Wang, H., & Dai, Y. (2019). Impairment of hypoxia-induced angiogenesis by LDL involves a HIF-centered signaling network linking inflammatory TNFα and angiogenic VEGF. Aging, 11, 328.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tsalamandris, S., Antonopoulos, A. S., Oikonomou, E., Papamikroulis, G.-A., Vogiatzi, G., Papaioannou, S., Deftereos, S., & Tousoulis, D. (2019). The role of inflammation in diabetes: current concepts and future perspectives. European Cardiology Review, 14, 50.

Article  PubMed  PubMed Central  Google Scholar 

Lajqi Berisha, N., Poceva Panovska, A., & Hajrulai-Musliu, Z. (2024). Antibiotic resistance and aquatic systems: Importance in public health. Water, 16, 2362.

Article  CAS  Google Scholar 

Sibiya, A., Jeyavani, J., Sivakamavalli, J., Ravi, C., Divya, M., & Vaseeharan, B. (2021). Bioactive compounds from various types of sea urchin and their therapeutic effects—a review. Regional Studies in Marine Science, 44, 101760.

Article  Google Scholar 

Khalil, E. A., Swelim, H., El-Tantawi, H., Bakr, A. F., & Abdellatif, A. (2022). Characterization, cytotoxicity and antioxidant activity of sea urchins (Diadema savignyi) and jellyfish (Aurelia Aurita) extracts. The Egyptian Journal of Aquatic Research, 48, 343–348.

Article  Google Scholar 

Ibrahim, H. A., Abdelnaby, H. M., Abouelkheir, S. S., Abo-Taleb, H. A., & Sersy, N. A. E. (2023). Blue economic potency of marine invertebrates for bio-drug discovery. Blue Economy, 1, 5.

Article  Google Scholar 

Shang, X.-H., Liu, X.-Y., Zhang, J.-P., Gao, Y., Jiao, B.-H., Zheng, H., & Lu, X.-L. (2014). Traditional Chinese Medicine——Sea Urchin. Mini Reviews in Medicinal Chemistry, 14, 537–542.

Article  CAS  PubMed  Google Scholar 

Soleimani, S., Yousefzadi, M., Moein, S., Rezadoost, H., & Bioki, N. A. (2016). Identification and antioxidant of polyhydroxylated naphthoquinone pigments from sea urchin pigments of Echinometra mathaei. Medicinal Chemistry Research, 25, 1476–1483.

Article  CAS  Google Scholar 

Chamika, W. A. S., Ho, T. C., Roy, V. C., Kiddane, A. T., Park, J.-S., Kim, G.-D., & Chun, B.-S. (2021). In vitro characterization of bioactive compounds extracted from sea urchin (Stomopneustes variolaris) using green and conventional techniques. Food Chemistry, 361, 129866.

Article  CAS  PubMed  Google Scholar 

Dursun, İ., Sağlamtaş, R., Fettahoğlu, K., Melek, Z., Sinan, A., Demirci, A., Demir, Y., & Gülçin, İ. (2024). Antioxidant and antimicrobial activities of different extracts of Tragopogon dubius and Tragopogon porrifolium L. subsp. longirostris: Determination of their phytochemical contents by UHPLC-Orbitrap®-HRMS analysis. Food Bioscience, 63, 105604.

Article  Google Scholar 

Salem, M. M., Donia, T., Abu-Khudir, R., Ramadan, H., Ali, E. M., & Mohamed, T. M. (2020). Propolis potentiates methotrexate anticancer mechanism and reduces its toxic effects. Nutrition and Cancer, 72, 460–480.

Article  CAS  PubMed  Google Scholar 

Ho, T. C., & Chun, B. S. (2019). Extraction of bioactive compounds from Pseuderanthemum palatiferum (Nees) Radlk. using subcritical water and conventional solvents: A comparison study. Journal of Food Science, 84, 1201–1207.

Article  CAS 

留言 (0)

沒有登入
gif