Transient activation of YAP/TAZ confers resistance to morusin-induced apoptosis

Ma S, Meng Z, Chen R, Guan KL. The Hippo Pathway: Biology and Pathophysiology. Annu Rev Biochem. 2019;88:577–604.

Article  CAS  PubMed  Google Scholar 

Fu M, Hu Y, Lan T, Guan KL, Luo T, Luo M. The Hippo signalling pathway and its implications in human health and diseases. Signal Transduct Target Ther. 2022;7(1):376.

Article  PubMed  PubMed Central  Google Scholar 

Cunningham R, Hansen CG. The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer. Clin Sci (Lond). 2022;136(3):197–222.

Article  CAS  PubMed  Google Scholar 

Driskill JH, Pan D. The Hippo Pathway in Liver Homeostasis and Pathophysiology. Annu Rev Pathol. 2021;16:299–322.

Article  CAS  PubMed  Google Scholar 

Wu S, Huang J, Dong J, Pan D. Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell. 2003;114(4):445–56.

Article  CAS  PubMed  Google Scholar 

Meng Z, Moroishi T, Guan KL. Mechanisms of Hippo pathway regulation. Genes Dev. 2016;30(1):1–17.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dey A, Varelas X, Guan KL. Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine. Nat Rev Drug Discov. 2020;19(7):480–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Harvey KF, Zhang X, Thomas DM. The Hippo pathway and human cancer. Nat Rev Cancer. 2013;13(4):246–57.

Article  CAS  PubMed  Google Scholar 

He M, Zhou Z, Shah AA, Hong Y, Chen Q, Wan Y. New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics. Cell Div. 2016;11:4.

Article  PubMed  PubMed Central  Google Scholar 

Liu H, Du S, Lei T, Wang H, He X, Tong R, et al. Multifaceted regulation and functions of YAP/TAZ in tumors (review). Oncol Rep. 2018;40(1):16–28.

PubMed  PubMed Central  Google Scholar 

Zhao B, Li L, Tumaneng K, Wang CY, Guan KL. A coordinated phosphorylation by lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev. 2010;24(1):72–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao B, Ye X, Yu J, Li L, Li W, Li S, et al. TEAD mediates YAP-dependent gene induction and growth control. Genes Dev. 2008;22(14):1962–71.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lüönd F, Pirkl M, Hisano M, Prestigiacomo V, Kalathur RK, Beerenwinkel N et al. Hierarchy of TGFβ/SMAD, Hippo/YAP/TAZ, and Wnt/β-catenin signaling in melanoma phenotype switching. Life Sci Alliance. 2022;5(2).

Passaniti A, Brusgard JL, Qiao Y, Sudol M, Finch-Edmondson M. Roles of RUNX in Hippo Pathway Signaling. Adv Exp Med Biol. 2017;962:435–48.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, et al. YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the wnt response. Cell. 2014;158(1):157–70.

Article  CAS  PubMed  Google Scholar 

Gao Y, Yang Y, Yuan F, Huang J, Xu W, Mao B, et al. TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration. Oncogenesis. 2017;6(9):e383.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang S, Xie F, Chu F, Zhang Z, Yang B, Dai T, et al. YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation. Nat Immunol. 2017;18(7):733–43.

Article  CAS  PubMed  Google Scholar 

Mo JS, Meng Z, Kim YC, Park HW, Hansen CG, Kim S, et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat Cell Biol. 2015;17(4):500–10.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang W, Xiao ZD, Li X, Aziz KE, Gan B, Johnson RL, et al. AMPK modulates Hippo pathway activity to regulate energy homeostasis. Nat Cell Biol. 2015;17(4):490–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Meng Z, Moroishi T, Mottier-Pavie V, Plouffe SW, Hansen CG, Hong AW, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357.

Article  CAS  PubMed  Google Scholar 

Das S, Khan TH, Sarkar D. Comprehensive Review on the Effect of Stem cells in Cancer Progression. Curr Tissue Microenvironment Rep. 2024;5(2):39–59.

Article  Google Scholar 

Wang Y, Yu A, Yu FX. The Hippo pathway in tissue homeostasis and regeneration. Protein Cell. 2017;8(5):349–59.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miao J, Hsu PC, Yang YL, Xu Z, Dai Y, Wang Y, et al. YAP regulates PD-L1 expression in human NSCLC cells. Oncotarget. 2017;8(70):114576–87.

Article  PubMed  PubMed Central  Google Scholar 

Tang D, Xu H, Du X. The role of non-canonical Hippo pathway in regulating immune homeostasis. Eur J Med Res. 2023;28(1):498.

Article  PubMed  PubMed Central  Google Scholar 

Mia MM, Singh MK. Emerging roles of the Hippo signaling pathway in modulating immune response and inflammation-driven tissue repair and remodeling. Febs j. 2022;289(14):4061–81.

Article  CAS  PubMed  Google Scholar 

Khan TH, Srivastava N, Srivastava A, Sareen A, Mathur RK, Chande AG, et al. SHP-1 plays a crucial role in CD40 signaling reciprocity. J Immunol. 2014;193(7):3644–53.

Article  CAS  PubMed  Google Scholar 

Zhang X, Kiapour N, Kapoor S, Khan T, Thamilarasan M, Tao Y, et al. IL-11 induces encephalitogenic Th17 cells in multiple sclerosis and experimental autoimmune encephalomyelitis. J Immunol. 2019;203(5):1142–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Seyedsadr M, Wang Y, Elzoheiry M, Shree Gopal S, Jang S, Duran G, et al. IL-11 induces NLRP3 inflammasome activation in monocytes and inflammatory cell migration to the central nervous system. Proc Natl Acad Sci U S A. 2023;120(26):e2221007120.

Article  PubMed  PubMed Central  Google Scholar 

Moya IM, Halder G. Hippo-YAP/TAZ signalling in organ regeneration and regenerative medicine. Nat Rev Mol Cell Biol. 2019;20(4):211–26.

Article  CAS  PubMed  Google Scholar 

Panek-Krzyśko A, Stompor-Gorący M. The Pro-health benefits of Morusin Administration-An Update Review. Nutrients. 2021;13(9).

Choi DW, Cho SW, Lee SG, Choi CY. The Beneficial effects of Morusin, an Isoprene Flavonoid isolated from the Root Bark of Morus. Int J Mol Sci. 2020;21(18):6541.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jia Y, He W, Zhang H, He L, Wang Y, Zhang T, et al. Morusin ameliorates IL-1β-Induced Chondrocyte inflammation and osteoarthritis via NF-κB Signal Pathway. Drug Des Devel Ther. 2020;14:1227–40.

Article  CAS  PubMed

留言 (0)

沒有登入
gif