Recent advances in self-targeting natural product-based nanomedicines

Long Q, Zhou W, Zhou H, Tang Y, Chen W, Liu Q, Bian X. Polyamine-containing natural products: structure, bioactivity, and biosynthesis. Nat Prod Rep. 2024;41:525–64.

Article  CAS  PubMed  Google Scholar 

Baunach M, Guljamow A, Miguel-Gordo M, Dittmann E. Harnessing the potential: advances in cyanobacterial natural product research and biotechnology. Nat Prod Rep. 2024;41:347–69.

Article  CAS  PubMed  Google Scholar 

Kong X, Liu C, Zhang Z, Cheng M, Mei Z, Li X, Liu P, Diao L, Ma Y, Jiang P, et al. BATMAN-TCM 20: an enhanced integrative database for known and predicted interactions between traditional Chinese medicine ingredients and target proteins. Nucleic Acids Res. 2024;52:1110–20.

Article  Google Scholar 

Zhang J, Pang H, Tang H, Tu Q, Xia F, Zhang H, Meng Y, Han G, Wang J, Qiu C. The pharmacodynamic and pharmacological mechanisms underlying nanovesicles of natural products: developments and challenges. Pharmacol Ther. 2025;265: 108754.

Article  CAS  PubMed  Google Scholar 

Guo X, Luo W, Wu L, Zhang L, Chen Y, Li T, Li H, Zhang W, Liu Y, Zheng J, Wang Y. Natural products from herbal medicine self-assemble into advanced bioactive materials. Adv Sci. 2024;11: e2403388.

Article  Google Scholar 

Xu K, Ren X, Wang J, Zhang Q, Fu X, Zhang PC. Clinical development and informatics analysis of natural and semi-synthetic flavonoid drugs: a critical review. J Adv Res. 2024;63:269–84.

Article  CAS  PubMed  Google Scholar 

Huang K, Zhang P, Zhang Z, Youn JY, Wang C, Zhang H, Cai H. Traditional Chinese medicine (TCM) in the treatment of COVID-19 and other viral infections: efficacies and mechanisms. Pharmacol Ther. 2021;225: 107843.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun R, Dai J, Ling M, Yu L, Yu Z, Tang L. Delivery of triptolide: a combination of traditional Chinese medicine and nanomedicine. J Nanobiotechnol. 2022;20:194.

Article  CAS  Google Scholar 

Ran B, Ren X, Lin X, Teng Y, Xin F, Ma W, Zhao X, Li M, Wang J, Wang C, et al. Glycyrrhetinic acid loaded in milk-derived extracellular vesicles for inhalation therapy of idiopathic pulmonary fibrosis. J Control Release. 2024;370:811–20.

Article  CAS  PubMed  Google Scholar 

Zhang S, Zhou R, Xie X, Xiong S, Li L, Li Y. Polysaccharides from Lycium barbarum, yam, and sunflower ameliorate colitis in a structure and intrinsic flora-dependent manner. Carbohydr Polym. 2025;349: 122905.

Article  CAS  PubMed  Google Scholar 

Ji R, Wang Z, Kuang H. Extraction, purification, structural characterization, and biological activity of polysaccharides from Schisandra chinensis: a review. Int J Biol Macromol. 2024;271: 132590.

Article  CAS  PubMed  Google Scholar 

Mao Q, Min J, Zeng R, Liu H, Li H, Zhang C, Zheng A, Lin J, Liu X, Wu M. Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy. Theranostics. 2022;12:6088–105.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang C, Li D, Ko CN, Wang K, Wang H. Active ingredients of traditional Chinese medicine for enhancing the effect of tumor immunotherapy. Front Immunol. 2023;14:1133050.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang Y, Zhang Q, Chen Y, Liang CL, Liu H, Qiu F, Dai Z. Antitumor effects of immunity-enhancing traditional Chinese medicine. Biomed Pharmacother. 2020;121: 109570.

Article  CAS  PubMed  Google Scholar 

Bu L, Dai O, Zhou F, Liu F, Chen JF, Peng C, Xiong L. Traditional Chinese medicine formulas, extracts, and compounds promote angiogenesis. Biomed Pharmacother. 2020;132: 110855.

Article  CAS  PubMed  Google Scholar 

Zhang X, Qiu H, Li C, Cai P, Qi F. The positive role of traditional Chinese medicine as an adjunctive therapy for cancer. Biosci Trends. 2021;15:283–98.

Article  CAS  PubMed  Google Scholar 

Zheng Y, Wang Y, Xia M, Gao Y, Zhang L, Song Y, Zhang C. The combination of nanotechnology and traditional Chinese medicine (TCM) inspires the modernization of TCM: review on nanotechnology in TCM-based drug delivery systems. Drug Deliv Transl Res. 2022;12:1306–25.

Article  PubMed  Google Scholar 

Zeng Q, Chen H, Wang Z, Guo Y, Wu Y, Hu Y, Liang P, Zheng Z, Liang T, Zhai D, et al. Carrier-free cryptotanshinone-peptide conjugates self-assembled nanoparticles: an efficient and low-risk strategy for acne vulgaris. Asian J Pharm Sci. 2024;19: 100946.

Article  PubMed  PubMed Central  Google Scholar 

Kan G, Chen L, Zhang W, Bian Q, Wang X, Zhong J. Recent advances in the development and application of curcumin-loaded micro/nanocarriers in food research. Adv Colloid Interface Sci. 2025;335: 103333.

Article  CAS  PubMed  Google Scholar 

Zdrojewicz Z, Waracki M, Bugaj B, Pypno D, Cabala K. Medical applications of nanotechnology. Postepy Hig Med Dosw. 2015;69:1196–204.

Article  Google Scholar 

Barrett T, Ravizzini G, Choyke PL, Kobayashi H. Dendrimers in medical nanotechnology. IEEE Eng Med Biol Mag. 2009;28:12–22.

Article  PubMed  PubMed Central  Google Scholar 

Zhu L, Torchilin VP. Stimulus-responsive nanopreparations for tumor targeting. Integr Biol (Camb). 2013;5:96–107.

Article  CAS  PubMed  Google Scholar 

Zou B, Long Y, Gao R, Liu Q, Tian X, Liu B, Zhou Q. Nanodelivery system of traditional Chinese medicine bioactive compounds: application in the treatment of prostate cancer. Phytomedicine. 2024;135: 155554.

Article  CAS  PubMed  Google Scholar 

Nath D, Banerjee P. Green nanotechnology—a new hope for medical biology. Environ Toxicol Pharmacol. 2013;36:997–1014.

Article  CAS  PubMed  Google Scholar 

Liu H, Luo GF, Shang Z. Plant-derived nanovesicles as an emerging platform for cancer therapy. Acta Pharm Sin B. 2024;14:133–54.

Article  PubMed  Google Scholar 

Huang Y, Zhao Y, Liu F, Liu S. Nano traditional Chinese medicine: current progresses and future challenges. Curr Drug Targets. 2015;16:1548–62.

Article  CAS  PubMed  Google Scholar 

Rahman HS, Othman HH, Hammadi NI, Yeap SK, Amin KM, Abdul Samad N, Alitheen NB. Novel drug delivery systems for loading of natural plant extracts and their biomedical applications. Int J Nanomed. 2020;15:2439–83.

Article  CAS  Google Scholar 

Guan J, Chen W, Yang M, Wu E, Qian J, Zhan C. Regulation of in vivo delivery of nanomedicines by herbal medicines. Adv Drug Deliv Rev. 2021;174:210–28.

Article  CAS  PubMed  Google Scholar 

Qiu C, Zhang JZ, Wu B, Xu CC, Pang HH, Tu QC, Lu YQ, Guo QY, Xia F, Wang JG. Advanced application of nanotechnology in active constituents of traditional Chinese medicines. J Nanobiotechnology. 2023;21:456.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu X, Zhao Y, Liang X, Ding Y, Hu J, Deng N, Zhao Y, Huang P, Xie W. In Vivo evaluation of self-assembled nano-saikosaponin-a for epilepsy treatment. Mol Biotechnol. 2023;66:2230–40.

Article  PubMed  Google Scholar 

Fu S, Yang X. Recent advances in natural small molecules as drug delivery systems. J Mater Chem B. 2023;11:4584–99.

Article  CAS  PubMed  Google Scholar 

Northrop BH, Zheng YR, Chi

留言 (0)

沒有登入
gif