Cazzola M, Myelodysplastic Syndromes. N Engl J Med. 2020;383(14):1358–74.

Article  CAS  PubMed  Google Scholar 

Goldberg SL, Chen E, Corral M, Guo A, Mody-Patel N, Pecora AL, et al. Incidence and clinical complications of myelodysplastic syndromes among United States Medicare beneficiaries. J Clin Oncol. 2010;28(17):2847–52.

Article  PubMed  Google Scholar 

Pang WW, Pluvinage JV, Price EA, Sridhar K, Arber DA, Greenberg PL, et al. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes. Proc Natl Acad Sci U S A. 2013;110(8):3011–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Garcia-Manero G. Myelodysplastic syndromes: 2023 update on diagnosis, risk-stratification, and management. Am J Hematol. 2023;98(8):1307–25.

Article  CAS  PubMed  Google Scholar 

Platzbecker U, Kubasch AS, Homer-Bouthiette C, Prebet T. Current challenges and unmet medical needs in myelodysplastic syndromes. Leukemia. 2021;35(8):2182–98.

Article  PubMed  PubMed Central  Google Scholar 

Sekeres MA, Taylor J. Diagnosis and treatment of myelodysplastic syndromes: a review. JAMA. 2022;328(9):872–80.

Article  PubMed  Google Scholar 

Zeidan AM, Shallis RM, Wang R, Davidoff A, Ma X. Epidemiology of myelodysplastic syndromes: why characterizing the beast is a prerequisite to taming it. Blood Rev. 2019;34:1–15.

Article  PubMed  Google Scholar 

Cogle CR. Incidence and burden of the myelodysplastic syndromes. Curr Hematol Malig Rep. 2015;10(3):272–81.

Article  PubMed  PubMed Central  Google Scholar 

Cogle CR, Craig BM, Rollison DE, List AF. Incidence of the myelodysplastic syndromes using a novel claims-based algorithm: high number of uncaptured cases by cancer registries. Blood. 2011;117(26):7121–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bejar R, Steensma DP. Recent developments in myelodysplastic syndromes. Blood. 2014;124(18):2793–803.

Article  CAS  PubMed  Google Scholar 

Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood. 2002;100(7):2292–302.

Article  CAS  PubMed  Google Scholar 

Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114(5):937–51.

Article  CAS  PubMed  Google Scholar 

Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20):2391–405.

Article  CAS  PubMed  Google Scholar 

Khoury JD, Solary E, Abla O, Akkari Y, Alaggio R, Apperley JF, et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: myeloid and Histiocytic/Dendritic neoplasms. Leukemia. 2022;36(7):1703–19.

Article  PubMed  PubMed Central  Google Scholar 

Saarni MI, Linman JW. Preleukemia. The hematologic syndrome preceding acute leukemia. Am J Med. 1973;55(1):38–48.

Article  CAS  PubMed  Google Scholar 

Ma X. Epidemiology of myelodysplastic syndromes. Am J Med. 2012;125(7 Suppl):S2–5.

Article  PubMed  PubMed Central  Google Scholar 

Sekeres MA. The epidemiology of myelodysplastic syndromes. Hematol Oncol Clin North Am. 2010;24(2):287–94.

Article  PubMed  Google Scholar 

Rotter LK, Shimony S, Ling K, Chen E, Shallis RM, Zeidan AM, et al. Epidemiology and Pathogenesis of Myelodysplastic Syndrome. Cancer J. 2023;29(3):111–21.

Article  CAS  PubMed  Google Scholar 

Guralnik JM, Eisenstaedt RS, Ferrucci L, Klein HG, Woodman RC. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004;104(8):2263–8.

Article  CAS  PubMed  Google Scholar 

Buckstein R, Jang K, Friedlich J, Zhang L, Reis M, Chesney A, et al. Estimating the prevalence of myelodysplastic syndromes in patients with unexplained cytopenias: a retrospective study of 322 bone marrows. Leuk Res. 2009;33(10):1313–8.

Article  PubMed  Google Scholar 

Cogle CR, Iannacone MR, Yu D, Cole AL, Imanirad I, Yan L, et al. High rate of uncaptured myelodysplastic syndrome cases and an improved method of case ascertainment. Leuk Res. 2014;38(1):71–5.

Article  PubMed  Google Scholar 

Xie M, Lu C, Wang J, McLellan MD, Johnson KJ, Wendl MC, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nat Med. 2014;20(12):1472–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Papaemmanuil E, Gerstung M, Malcovati L, Tauro S, Gundem G, Van Loo P, et al. Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood. 2013;122(22):3616–27. quiz 99.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bejar R, CHIP, ICUS. CCUS and other four-letter words. Leukemia. 2017;31(9):1869–71.

Article  CAS  PubMed  Google Scholar 

DeZern AE, Malcovati L, Ebert BL. CHIP, CCUS, and Other Acronyms: Definition, Implications, and Impact on Practice. 2019(39):400– 10.

Sekeres MA, Schoonen WM, Kantarjian H, List A, Fryzek J, Paquette R, et al. Characteristics of US patients with myelodysplastic syndromes: results of six cross-sectional physician surveys. J Natl Cancer Inst. 2008;100(21):1542–51.

Article  PubMed  PubMed Central  Google Scholar 

Goksu SY, Ozer M, Goksu BB, Wang R, Khatib J, Patel PA, et al. The impact of race and ethnicity on outcomes of patients with myelodysplastic syndromes: a population-based analysis. Leuk Lymphoma. 2022;63(7):1651–9.

Article  PubMed  Google Scholar 

Lesegretain A, Brunner A, King AJ, Laadem A, Fell G, Fathi AT. Comparison of demographics, disease characteristics, and outcomes between Black and White patients with myelodysplastic syndromes: a population-based study. Leuk Res. 2023;125:107006.

Article  PubMed  Google Scholar 

Molina A, Xiao L, Ostrom QT, Rosas LG, Greenberg PL. Epidemiologic evaluation of clinical outcomes in ethnic minorities with myelodysplastic syndromes. Leuk Res. 2022;119:106907.

Article  PubMed  Google Scholar 

Avgerinou C, Alamanos Y, Zikos P, Lampropoulou P, Melachrinou M, Labropoulou V, et al. The incidence of myelodysplastic syndromes in Western Greece is increasing. Ann Hematol. 2013;92(7):877–87.

Article  PubMed  PubMed Central  Google Scholar 

Dinmohamed AG, Visser O, van Norden Y, Huijgens PC, Sonneveld P, van de Loosdrecht AA, et al. Trends in incidence, initial treatment and survival of myelodysplastic syndromes: a population-based study of 5144 patients diagnosed in the Netherlands from 2001 to 2010. Eur J Cancer. 2014;50(5):1004–12.

Article  PubMed  Google Scholar 

McQuilten ZK, Polizzotto MN, Wood EM, Sundararajan V. Myelodysplastic syndrome incidence, transfusion dependence, health care use, and complications: an Australian population-based study 1998 to 2008. Transfusion. 2013;53(8):1714–21.

Article  PubMed  Google Scholar 

Neukirchen J, Schoonen WM, Strupp C, Gattermann N, Aul C, Haas R, et al. Incidence and prevalence of myelodysplastic syndromes: data from the Dusseldorf MDS-registry. Leuk Res. 2011;35(12):1591–6.

Article