Davis LE, Shalin SC, Tackett AJ. Current state of melanoma diagnosis and treatment. Cancer Biol Ther. 2019;20(11):1366–79. https://doi.org/10.1080/15384047.2019.1640032.
Article CAS PubMed PubMed Central Google Scholar
Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74(1):12–49. https://doi.org/10.3322/caac.21820.
Ertekin SS, Podlipnik S, Riquelme-Mc Loughlin C, Barreiro-Capurro A, Arance A, Carrera C, et al. Initial stage of cutaneous primary melanoma plays a key role in the pattern and timing of disease recurrence. Acta Derm Venereol. 2021;101(7):adv00502. https://doi.org/10.2340/00015555-3832.
Zhou C, Louwman M, Wakkee M, van der Veldt A, Grünhagen D, Verhoef C, et al. Primary melanoma characteristics of metastatic disease: a nationwide cancer registry study. Cancers (Basel). 2021;13(17):4431. https://doi.org/10.3390/cancers13174431.
Sussman TA, Ott PA. Adjuvant immunotherapy for melanoma patients: progress and opportunities. ESMO Open. 2024;9(5):102962. https://doi.org/10.1016/j.esmoop.2024.102962.
Article CAS PubMed PubMed Central Google Scholar
Filin IY, Mayasin YP, Kharisova CB, Gorodilova AV, Kitaeva KV, Chulpanova DS, et al. Cell immunotherapy against melanoma: clinical trials review. Int J Mol Sci. 2023;24(3):2413. https://doi.org/10.3390/ijms24032413.
Article CAS PubMed PubMed Central Google Scholar
Long GV, Menzies AM, Scolyer RA. Neoadjuvant checkpoint immunotherapy and melanoma: the time is now. J Clin Oncol. 2023;41(17):3236–48. https://doi.org/10.1200/jco.22.02575.
Article CAS PubMed Google Scholar
Lazaroff J, Bolotin D. Targeted therapy and immunotherapy in melanoma. Dermatol Clin. 2023;41(1):65–77. https://doi.org/10.1016/j.det.2022.07.007.
Article CAS PubMed Google Scholar
Lu Y, Li Z, Zhang S, Zhang T, Liu Y, Zhang L. Cellular mitophagy: mechanism, roles in diseases and small molecule pharmacological regulation. Theranostics. 2023;13(2):736–66. https://doi.org/10.7150/thno.79876.
Article CAS PubMed PubMed Central Google Scholar
Picca A, Faitg J, Auwerx J, Ferrucci L, D’Amico D. Mitophagy in human health, ageing and disease. Nat Metab. 2023;5(12):2047–61. https://doi.org/10.1038/s42255-023-00930-8.
Wang S, Long H, Hou L, Feng B, Ma Z, Wu Y, et al. The mitophagy pathway and its implications in human diseases. Signal Transduct Target Ther. 2023;8(1):304. https://doi.org/10.1038/s41392-023-01503-7.
Article PubMed PubMed Central Google Scholar
Panigrahi DP, Praharaj PP, Bhol CS, Mahapatra KK, Patra S, Behera BP, et al. The emerging, multifaceted role of mitophagy in cancer and cancer therapeutics. Semin Cancer Biol. 2020;66:45–58. https://doi.org/10.1016/j.semcancer.2019.07.015.
Article CAS PubMed Google Scholar
Song C, Pan S, Zhang J, Li N, Geng Q. Mitophagy: a novel perspective for insighting into cancer and cancer treatment. Cell Prolif. 2022;55(12):e13327. https://doi.org/10.1111/cpr.13327.
Article CAS PubMed PubMed Central Google Scholar
Yao J, Wang J, Xu Y, Guo Q, Sun Y, Liu J, et al. CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma. Autophagy. 2022;18(8):1879–97. https://doi.org/10.1080/15548627.2021.2007027.
Article CAS PubMed Google Scholar
Deng R, Zhang HL, Huang JH, Cai RZ, Wang Y, Chen YH, et al. MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis. Autophagy. 2021;17(10):3011–29. https://doi.org/10.1080/15548627.2020.1850609.
Article CAS PubMed Google Scholar
Meng Y, Qiu L, Zeng X, Hu X, Zhang Y, Wan X, et al. Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy. Signal Transduct Target Ther. 2022;7(1):388. https://doi.org/10.1038/s41392-022-01253-y.
Article CAS PubMed PubMed Central Google Scholar
Wang H, Yi X, Guo S, Wang S, Ma J, Zhao T, et al. The XBP1-MARCH5-MFN2 axis confers endoplasmic reticulum stress resistance by coordinating mitochondrial fission and mitophagy in melanoma. J Invest Dermatol. 2021;141(12):2932-43.e12. https://doi.org/10.1016/j.jid.2021.03.031.
Article CAS PubMed Google Scholar
Vara-Pérez M, Rossi M, Van den Haute C, Maes H, Sassano ML, Venkataramani V, et al. BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis. EMBO J. 2021;40(10):e106214. https://doi.org/10.15252/embj.2020106214.
Article CAS PubMed PubMed Central Google Scholar
Sun J, Ding J, Yue H, Xu B, Sodhi A, Xue K, et al. Hypoxia-induced BNIP3 facilitates the progression and metastasis of uveal melanoma by driving metabolic reprogramming. Autophagy. 2024;21:191–209. https://doi.org/10.1080/15548627.2024.2395142.
Article CAS PubMed Google Scholar
Liu Z, Qin G, Yang J, Wang W, Zhang W, Lu B, et al. Targeting mitochondrial degradation by chimeric autophagy-tethering compounds. Chem Sci. 2023;14(40):11192–202. https://doi.org/10.1039/d3sc03600f.
Article CAS PubMed PubMed Central Google Scholar
Vara-Pérez M, Agostinis P. BNIP3 in melanoma: isnʼt it IRONic? Mol Cell Oncol. 2021;8(4):1947169. https://doi.org/10.1080/23723556.2021.1947169.
Article CAS PubMed PubMed Central Google Scholar
Stuart T, Butler A, Hoffman P, Hafemeister C, Papalexi E, Mauck WM 3rd, et al. Comprehensive integration of single-cell data. Cell. 2019;177(7):1888-902.e21. https://doi.org/10.1016/j.cell.2019.05.031.
Article CAS PubMed PubMed Central Google Scholar
Langfelder P, Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinform. 2008;9:559. https://doi.org/10.1186/1471-2105-9-559.
Xu L, Deng C, Pang B, Zhang X, Liu W, Liao G, et al. TIP: a web server for resolving tumor immunophenotype profiling. Cancer Res. 2018;78(23):6575–80. https://doi.org/10.1158/0008-5472.Can-18-0689.
Article CAS PubMed Google Scholar
Chan TA, Yarchoan M, Jaffee E, Swanton C, Quezada SA, Stenzinger A, et al. Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic. Ann Oncol. 2019;30(1):44–56. https://doi.org/10.1093/annonc/mdy495.
Article CAS PubMed Google Scholar
Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity. 2013;39(1):1–10. https://doi.org/10.1016/j.immuni.2013.07.012.
Article CAS PubMed Google Scholar
Basit F, van Oppen LM, Schöckel L, Bossenbroek HM, van Emst-de Vries SE, Hermeling JC, et al. Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells. Cell Death Dis. 2017;8(3):e2716. https://doi.org/10.1038/cddis.2017.133.
留言 (0)