Hadjidakis DJ, Androulakis II (2006) Bone remodeling. Ann N Y Acad Sci 1092:385–396
Article CAS PubMed Google Scholar
Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ (1999) Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 20:345–357
Article CAS PubMed Google Scholar
Boyle WJ, Simonet WS, Lacey DL (2003) Osteoclast differentiation and activation. Nature 423:337–342
Article CAS PubMed Google Scholar
Pixley FJ, Stanley ER (2004) CSF-1 regulation of the wandering macrophage: complexity in action. Trends Cell Biol 14:628–638
Article CAS PubMed Google Scholar
Feng W, Xia W, Ye Q, Wu W (2014) Osteoclastogenesis and osteoimmunology. Front Biosci (Landmark Ed) 19:758–767
Stanley ER, Chitu V (2014) CSF-1 receptor signaling in myeloid cells. Cold Spring Harb Perspect Biol 6:e021857
Park JH, Lee NK, Lee SY (2017) Current Understanding of RANK Signaling in Osteoclast Differentiation and Maturation. Mol Cells 40:706–713
Article CAS PubMed PubMed Central Google Scholar
Zou W, Kitaura H, Reeve J, Long F, Tybulewicz VL, Shattil SJ, Ginsberg MH, Ross FP, Teitelbaum SL (2007) Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. J Cell Biol 176:877–888
Article CAS PubMed PubMed Central Google Scholar
Teitelbaum SL (2006) Osteoclasts and integrins. Ann N Y Acad Sci 1068:95–99
Article CAS PubMed Google Scholar
Mori Y, Tsuji S, Inui M, Sakamoto Y, Endo S, Ito Y, Fujimura S, Koga T, Nakamura A, Takayanagi H, Itoi E, Takai T (2008) Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development. J Immunol 181:4742–4751
Article CAS PubMed Google Scholar
Sheng MH, Amoui M, Stiffel V, Srivastava AK, Wergedal JE, Lau KH (2009) Targeted transgenic expression of an osteoclastic transmembrane protein-tyrosine phosphatase in cells of osteoclastic lineage increases bone resorption and bone loss in male young adult mice. J Biol Chem 284:11531–11545
Article CAS PubMed PubMed Central Google Scholar
Lau KH, Wu LW, Sheng MH, Amoui M, Suhr SM, Baylink DJ (2006) An osteoclastic protein-tyrosine phosphatase is a potential positive regulator of the c-Src protein-tyrosine kinase activity: a mediator of osteoclast activity. J Cell Biochem 97:940–955
Article CAS PubMed Google Scholar
Lau KH, Amoui M, Stiffel V, Chen ST, Sheng MH (2015) An osteoclastic transmembrane protein-tyrosine phosphatase enhances osteoclast activity in part by dephosphorylating EphA4 in osteoclasts. J Cell Biochem 116:1785–1796
Article CAS PubMed Google Scholar
Amoui M, Sheng MH, Chen ST, Baylink DJ, Lau KH (2007) A transmembrane osteoclastic protein-tyrosine phosphatase regulates osteoclast activity in part by promoting osteoclast survival through c-Src-dependent activation of NFkappaB and JNK2. Arch Biochem Biophys 463:47–59
Article CAS PubMed Google Scholar
Wu LW, Baylink DJ, Lau KH (1996) Molecular cloning and expression of a unique rabbit osteoclastic phosphotyrosyl phosphatase. Biochem J 316(Pt 2):515–523
Article CAS PubMed PubMed Central Google Scholar
Stiffel V, Amoui M, Sheng MH, Mohan S, Lau KH (2014) EphA4 receptor is a novel negative regulator of osteoclast activity. J Bone Miner Res 29:804–819
Article CAS PubMed Google Scholar
Yang JH, Amoui M, Strong DD, Lau KH (2007) Characterization and comparison of the intronic promoter of murine osteoclastic protein-tyrosine phosphatase, PTP-oc, with the human PTP-oc promoter. Arch Biochem Biophys 465:72–81
Article CAS PubMed Google Scholar
Lau KW, Stiffel VM, Rundle CH, Amoui M, Tapia J, White TD, Sheng MH (2017) Conditional disruption of miR17~92 in osteoclasts led to activation of osteoclasts and loss of trabecular bone in part through suppression of the miR17-mediated downregulation of protein-tyrosine phosphatase-oc in mice. JBMR Plus 1:73–85
Article CAS PubMed PubMed Central Google Scholar
Lau KW, Sheng MH (2018) A novel miR17/protein tyrosine phosphatase-oc/EphA4 regulatory axis of osteoclast activity. Arch Biochem Biophys 650:30–38
Article CAS PubMed PubMed Central Google Scholar
Black DM, Thompson DE, Bauer DC, Ensrud K, Musliner T, Hochberg MC, Nevitt MC, Suryawanshi S, Cummings SR, Fracture Intervention T (2000) Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group. J Clin Endocrinol Metab 85:4118–4124
Article CAS PubMed Google Scholar
Cummings SR, San Martin J, McClung MR, Siris ES, Eastell R, Reid IR, Delmas P, Zoog HB, Austin M, Wang A, Kutilek S, Adami S, Zanchetta J, Libanati C, Siddhanti S, Christiansen C, Trial F (2009) Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 361:756–765
Article CAS PubMed Google Scholar
McClung MR (2017) Sclerostin antibodies in osteoporosis: latest evidence and therapeutic potential. Ther Adv Musculoskelet Dis 9:263–270
Article CAS PubMed PubMed Central Google Scholar
Doench JG, Sharp PA (2004) Specificity of microRNA target selection in translational repression. Genes Dev 18:504–511
Article CAS PubMed PubMed Central Google Scholar
Sheng MH, Lau KH, Beamer WG, Baylink DJ, Wergedal JE (2004) In vivo and in vitro evidence that the high osteoblastic activity in C3H/HeJ mice compared to C57BL/6J mice is intrinsic to bone cells. Bone 35:711–719
Article CAS PubMed Google Scholar
Schmittgen TD, Livak KJ (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3:1101–1108
Article CAS PubMed Google Scholar
Suhr SM, Pamula S, Baylink DJ, Lau KH (2001) Antisense oligodeoxynucleotide evidence that a unique osteoclastic protein-tyrosine phosphatase is essential for osteoclastic resorption. J Bone Miner Res 16:1795–1803
Article CAS PubMed Google Scholar
Gao Y, Li J, Zhang Z, Zhang R, Pollock A, Sun T (2019) MicroRNA miR-7 and miR-17-92 in the arcuate nucleus of mouse hypothalamus regulate sex-specific diet-induced obesity. Mol Neurobiol 56:7508–7521
Article CAS PubMed Google Scholar
Zhou Y, Zhang L, Ji H, Lu X, Xia J, Li L, Chen F, Bu H, Shi Y (2016) MiR-17~92 ablation impairs liver regeneration in an estrogen-dependent manner. J Cell Mol Med 20:939–948
Article CAS PubMed PubMed Central Google Scholar
Castellano L, Giamas G, Jacob J, Coombes RC, Lucchesi W, Thiruchelvam P, Barton G, Jiao LR, Wait R, Waxman J, Hannon GJ, Stebbing J (2009) The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response. Proc Natl Acad Sci U S A 106:15732–15737
Article CAS PubMed PubMed Central Google Scholar
Mohan S, Wergedal JE, Das S, Kesavan C (2015) Conditional disruption of miR17-92 cluster in collagen type I-producing osteoblasts results in reduced periosteal bone formation and bone anabolic response to exercise. Physiol Genomics 47:33–43
留言 (0)