Alzahrani S, Ezzat W, Elshaer RE, El-Lateef A, Mohammad AS, Elkazaz HMF, Zaitone AY, S. A (2018) Standarized Tribulus terrestris extract protects against rotenone-induced oxidative damage and nigral dopamine neuronal loss in mice. J Physiol Pharmacol 69(6). https://doi.org/10.26402/jpp.2018.6.14
Anfinogenova ND, Quinn MT, Schepetkin IA, Atochin DN (2020) Alarmins and c-Jun N-Terminal kinase (JNK) signaling in neuroinflammation. Cells 9(11). https://doi.org/10.3390/cells9112350
Arena G, Sharma K, Agyeah G, Kruger R, Grunewald A, Fitzgerald JC (2022) Neurodegeneration and neuroinflammation in Parkinson’s disease: a self-sustained loop. Curr Neurol Neurosci Rep 22(8):427–440. https://doi.org/10.1007/s11910-022-01207-5
Baquet ZC, Williams D, Brody J, Smeyne RJ (2009) A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse. Neuroscience 161(4):1082–1090. https://doi.org/10.1016/j.neuroscience.2009.04.031
Article CAS PubMed Google Scholar
Becher B, Spath S, Goverman J (2017) Cytokine networks in neuroinflammation. Nat Rev Immunol 17(1):49–59. https://doi.org/10.1038/nri.2016.123
Article CAS PubMed Google Scholar
Bohush A, Niewiadomska G, Filipek A (2018) Role of mitogen activated protein kinase signaling in Parkinson’s Disease. Int J Mol Sci 19(10). https://doi.org/10.3390/ijms19102973
Boyd JD, Jang H, Shepherd KR, Faherty C, Slack S, Jiao Y, Smeyne RJ (2007) Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta. Brain Res 1175:107–116. https://doi.org/10.1016/j.brainres.2007.07.067
Article CAS PubMed PubMed Central Google Scholar
Chauhdary Z, Saleem U, Ahmad B, Shah S, Shah MA (2019) Neuroprotective evaluation of Tribulus terrestris L. in aluminum chloride induced Alzheimer’s disease. Pak J Pharm Sci 32(2):805–816
Chien CH, Lee MJ, Liou HC, Liou HH, Fu WM (2016) Microglia-Derived Cytokines/Chemokines are involved in the enhancement of LPS-Induced loss of Nigrostriatal Dopaminergic Neurons in DJ-1 knockout mice. PLoS ONE 11(3):e0151569. https://doi.org/10.1371/journal.pone.0151569
Article CAS PubMed PubMed Central Google Scholar
Crocker CE, Khan S, Cameron MD, Robertson HA, Robertson GS, Lograsso P (2011) JNK Inhibition protects dopamine neurons and provides behavioral improvement in a rat 6-hydroxydopamine model of Parkinson’s Disease. ACS Chem Neurosci 2(4):207–212. https://doi.org/10.1021/cn1001107
Article CAS PubMed PubMed Central Google Scholar
Gauthaman K, Ganesan AP (2008) The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction–an evaluation using primates, rabbit and rat. Phytomedicine 15(1–2):44–54. https://doi.org/10.1016/j.phymed.2007.11.011
Article CAS PubMed Google Scholar
Huh E, Choi JG, Sim Y, Oh MS (2018) An integrative approach to treat Parkinson’s disease: Ukgansan complements L-Dopa by ameliorating dopaminergic neuronal damage and L-Dopa-Induced Dyskinesia in mice. Front Aging Neurosci 10:431. https://doi.org/10.3389/fnagi.2018.00431
Article CAS PubMed Google Scholar
John GR, Lee SC, Brosnan CF (2003) Cytokines: powerful regulators of glial cell activation. Neuroscientist 9(1):10–22. https://doi.org/10.1177/1073858402239587
Article CAS PubMed Google Scholar
Ju IG, Huh E, Kim N, Lee S, Choi JG, Hong J, Oh MS (2021) Artemisiae Iwayomogii Herba inhibits lipopolysaccharide-induced neuroinflammation by regulating NF-kappaB and MAPK signaling pathways. Phytomedicine 84:153501. https://doi.org/10.1016/j.phymed.2021.153501
Article CAS PubMed Google Scholar
Kwon HS, Koh SH (2020) Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes. Transl Neurodegener 9(1):42. https://doi.org/10.1186/s40035-020-00221-2
Article PubMed PubMed Central Google Scholar
Lee S, Ju IG, Choi Y, Park S, Oh MS (2021) Trichosanthis Semen suppresses Lipopolysaccharide-Induced Neuroinflammation by regulating the NF-kappaB signaling pathway and HO-1 expression in Microglia. Toxins (Basel) 13(12). https://doi.org/10.3390/toxins13120898
Li D, Li X, Wu J, Li J, Zhang L, Xiong T, Mu D (2015) Involvement of the JNK/FOXO3a/Bim pathway in neuronal apoptosis after hypoxic-ischemic brain damage in neonatal rats. PLoS ONE 10(7):e0132998. https://doi.org/10.1371/journal.pone.0132998
Article CAS PubMed PubMed Central Google Scholar
Ma Y, Guo Z, Wang X (2017) Tribulus terrestris extracts alleviate muscle damage and promote anaerobic performance of trained male boxers and its mechanisms: roles of androgen, IGF-1, and IGF binding protein-3. J Sport Health Sci 6(4):474–481. https://doi.org/10.1016/j.jshs.2015.12.003
Mamelak M (2018) Parkinson’s disease, the dopaminergic neuron and gammahydroxybutyrate. Neurol Ther 7(1):5–11. https://doi.org/10.1007/s40120-018-0091-2
Article PubMed PubMed Central Google Scholar
Marsden CD (1994) Problems with long-term levodopa therapy for Parkinson’s disease. Clin Neuropharmacol 17(Suppl 2):S32–44
Ou Z, Pan J, Tang S, Duan D, Yu D, Nong H, Wang Z (2021) Global trends in the incidence, prevalence, and years lived with disability of Parkinson’s disease in 204 countries/territories from 1990 to 2019. Front Public Health 9:776847. https://doi.org/10.3389/fpubh.2021.776847
Article PubMed PubMed Central Google Scholar
Parveen R, Wadud A, Shamsi S, Parveen S (2021) Antilithiatic activity of a non-pharmacopoeial Unani formulation in chemically induced urolithiasis in rats. J Complement Integr Med 18(4):685–694. https://doi.org/10.1515/jcim-2020-0426
Article CAS PubMed Google Scholar
Qiu M, An M, Bian M, Yu S, Liu C, Liu Q (2019) Terrestrosin D from Tribulus terrestris attenuates bleomycin-induced inflammation and suppresses fibrotic changes in the lungs of mice. Pharm Biol 57(1):694–700. https://doi.org/10.1080/13880209.2019.1672754
Article CAS PubMed PubMed Central Google Scholar
Salat D, Tolosa E (2013) Levodopa in the treatment of Parkinson’s disease: current status and new developments. J Parkinsons Dis 3(3):255–269. https://doi.org/10.3233/JPD-130186
Article CAS PubMed Google Scholar
Saleem U, Chauhdary Z, Raza Z, Shah S, Rahman MU, Zaib P, Ahmad B (2020) Anti-parkinson’s activity of Tribulus terrestris via modulation of AChE, alpha-Synuclein, TNF-alpha, and IL-1beta. ACS Omega 5(39):25216–25227. https://doi.org/10.1021/acsomega.0c03375
Article CAS PubMed PubMed Central Google Scholar
Spigolon G, Cavaccini A, Trusel M, Tonini R, Fisone G (2018) cJun N-terminal kinase (JNK) mediates cortico-striatal signaling in a model of Parkinson’s disease. Neurobiol Dis 110:37–46. https://doi.org/10.1016/j.nbd.2017.10.015
Article CAS PubMed Google Scholar
Wang W, Ma C, Mao Z, Li M (2004) JNK inhibition as a potential strategy in treating Parkinson’s disease. Drug News Perspect 17(10):646–654. https://doi.org/10.1358/dnp.2004.17.10.873916
Article CAS PubMed Google Scholar
Wang Y, Guo W, Xie S, Liu Y, Xu D, Chen G, Xu Y (2021) Multi-omics analysis of brain tissue metabolome and proteome reveals the protective effect of gross saponins of Tribulus terrestris L. fruit against ischemic stroke in rat. J Ethnopharmacol 278:114280. https://doi.org/10.1016/j.jep.2021.114280
Article CAS PubMed Google Scholar
Xu X, Raber J, Yang D, Su B, Mucke L (1997) Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli. Proc Natl Acad Sci U S A 94(23):12655–12660. https://doi.org/10.1073/pnas.94.23.12655
Article CAS PubMed PubMed Central Google Scholar
Zhang W, Xiao D, Mao Q, Xia H (2023) Role of neuroinflammation in neurodegeneration development. Signal Transduct Target Ther 8(1):267. https://doi.org/10.1038/s41392-023-01486-5
留言 (0)