Abbott NJ, Friedman A (2012) Overview and introduction: the blood-brain barrier in health and disease. Epilepsia 53 53(Suppl 6):1–6. https://doi.org/10.1111/j.1528-1167.2012.03696.x

Article  Google Scholar 

Abbott NJ, Patabendige AAK, Dolman DEM et al (2010) Structure and function of the blood-brain barrier. Neurobiol Dis 37:13–25. https://doi.org/10.1016/j.nbd.2009.07.030

Article  CAS  PubMed  Google Scholar 

Adesso S, Magnus T, Cuzzocrea S et al (2017) Indoxyl sulfate affects glial function increasing oxidative stress and neuroinflammation in chronic kidney disease: Interaction between astrocytes and Microglia. Front Pharmacol 8:370. https://doi.org/10.3389/fphar.2017.00370

Article  CAS  PubMed  PubMed Central  Google Scholar 

Adesso S, Paterniti I, Cuzzocrea S et al (2018) AST-120 reduces Neuroinflammation Induced by Indoxyl Sulfate in glial cells. J Clin Med 7:365. https://doi.org/10.3390/jcm7100365

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ahmad AA, Gassmann M, Ogunshola OO (2012) Involvement of oxidative stress in hypoxia-induced blood–brain barrier breakdown. Microvasc Res 84:222–225. https://doi.org/10.1016/j.mvr.2012.05.008

Article  CAS  PubMed  Google Scholar 

Alblooshi S, Taylor M, Gill N (2023) Does menopause elevate the risk for developing depression and anxiety? Results from a systematic review. Australas Psychiatry 31:165–173. https://doi.org/10.1177/10398562231165439

Article  PubMed  PubMed Central  Google Scholar 

Albrecht ED, Pepe GJ (2010) Estrogen regulation of placental angiogenesis and fetal ovarian development during primate pregnancy. Int J Dev Biol 54:397–408. https://doi.org/10.1387/ijdb.082758ea

Article  CAS  PubMed  PubMed Central  Google Scholar 

America M, Bostaille N, Eubelen M et al (2022) An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates. Cell Rep 39:110902. https://doi.org/10.1016/j.celrep.2022.110902

Article  CAS  PubMed  PubMed Central  Google Scholar 

Anastasio TJ (2013) Exploring the contribution of estrogen to amyloid-Beta regulation: a Novel Multifactorial Computational modeling Approach. Front Pharmacol 4:16. https://doi.org/10.3389/fphar.2013.00016

Article  PubMed  PubMed Central  Google Scholar 

Argaw AT, Zhang Y, Snyder BJ et al (2006) IL-1β regulates blood-brain barrier permeability via reactivation of the Hypoxia-Angiogenesis Program. J Immunol 177:5574–5584. https://doi.org/10.4049/jimmunol.177.8.5574

Article  CAS  PubMed  Google Scholar 

Armulik A, Genové G, Mäe M et al (2010) Pericytes regulate the blood–brain barrier. Nature 468:557–561. https://doi.org/10.1038/nature09522

Article  CAS  PubMed  Google Scholar 

Arnold R, Issar T, Krishnan AV, Pussell BA (2016) Neurological complications in chronic kidney disease. JRSM Cardiovasc Dis 5:2048004016677687. https://doi.org/10.1177/2048004016677687

Article  PubMed  PubMed Central  Google Scholar 

Arnold SE, Arvanitakis Z, Macauley-Rambach SL et al (2018) Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums. Nat Rev Neurol 14:168–181. https://doi.org/10.1038/nrneurol.2017.185

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arthur FE, Shivers RR, Bowman PD (1987) Astrocyte-mediated induction of tight junctions in brain capillary endothelium: an efficient in vitro model. Dev Brain Res 36:155–159. https://doi.org/10.1016/0165-3806(87)90075-7

Article  Google Scholar 

Aslam M, Ahmad N, Srivastava R, Hemmer B (2012) TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells. Cytokine 57:269–275. https://doi.org/10.1016/j.cyto.2011.10.016

Article  CAS  PubMed  Google Scholar 

Assem M, Lando M, Grissi M et al (2018) The impact of Uremic Toxins on Cerebrovascular and Cognitive disorders. Toxins 10:303. https://doi.org/10.3390/toxins10070303

Article  CAS  PubMed  PubMed Central  Google Scholar 

Atallah A, Mhaouty-Kodja S, Grange-Messent V (2016) Chronic depletion of gonadal testosterone leads to blood–brain barrier dysfunction and inflammation in male mice. J Cereb Blood Flow Metab 37:3161–3175. https://doi.org/10.1177/0271678x16683961

Article  CAS  PubMed  PubMed Central  Google Scholar 

Banks WA, Erickson MA (2010) The blood–brain barrier and immune function and dysfunction. Neurobiol Dis 37:26–32. https://doi.org/10.1016/j.nbd.2009.07.031

Article  CAS  PubMed  Google Scholar 

Banoglu E, Jha GG, King RS (2001) Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate. Eur J Drug Metab Pharmacokinet 26:235–240. https://doi.org/10.1007/bf03226377

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barisano G, Montagne A, Kisler K et al (2022) Blood–brain barrier link to human cognitive impairment and Alzheimer’s disease. Nat Cardiovasc Res 1:108–115. https://doi.org/10.1038/s44161-021-00014-4

Article  PubMed  PubMed Central  Google Scholar 

Ben-Zvi A, Liebner S (2021) Developmental regulation of barrier‐ and non‐barrier blood vessels in the CNS. J Intern Med. https://doi.org/10.1111/joim.13263

Article  PubMed  Google Scholar 

Benz F, Liebner S (2022) Structure and function of the blood-brain barrier (BBB). Handb Exp Pharmacol 273:3–31. https://doi.org/10.1007/164_2020_404

Bernard A, Ku JM, Vlahos R, Miller AA (2019) Cigarette smoke extract exacerbates hyperpermeability of cerebral endothelial cells after oxygen glucose deprivation and reoxygenation. Sci Rep 9:15573. https://doi.org/10.1038/s41598-019-51728-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Betjes MGH, Langerak AW, Spek A, van der et al (2011) Premature aging of circulating T cells in patients with end-stage renal disease. Kidney Int 80:208–217. https://doi.org/10.1038/ki.2011.110

Article  PubMed  Google Scholar 

Bhalerao A, Sivandzade F, Archie SR et al (2020) In vitro modeling of the neurovascular unit: advances in the field. Fluids Barriers CNS 17:22. https://doi.org/10.1186/s12987-020-00183-7

Article  PubMed  PubMed Central  Google Scholar 

Bichet DG (2018) Vasopressin and the Regulation of Thirst. Annals of nutrition & metabolism 72(Suppl 2):3–7. https://doi.org/10.1159/000488233

Article  CAS  Google Scholar 

Bjerring OJ, LG YH, Anne-Lise K et al (2012) Stroke and bleeding in Atrial Fibrillation with chronic kidney disease. N Engl J Med 367:625–635. https://doi.org/10.1056/nejmoa1105594

Article  Google Scholar 

Bobot M, Thomas L, Moyon A et al (2020) Uremic toxic blood-brain barrier disruption mediated by AhR activation leads to cognitive impairment during experimental renal dysfunction. J Am Soc Nephrol 31:1509–1521. https://doi.org/10.1681/asn.2019070728

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brandebura AN, Paumier A, Onur TS, Allen NJ (2023) Astrocyte contribution to dysfunction, risk and progression in neurodegenerative disorders. Nat Rev Neurosci 24:23–39. https://doi.org/10.1038/s41583-022-00641-1

Article  CAS  PubMed  Google Scholar 

Braniste V, Al-Asmakh M, Kowal C et al (2014) The gut microbiota influences blood-brain barrier permeability in mice. Sci Transl Med 6:263ra158–263ra158.