Ex Vivo Human Tissue Functions as a Testing Platform for the Evaluation of a Nerve-Specific Fluorophore

Robinson LR (2000) Traumatic injury to peripheral nerves. Muscle Nerve 23(6):863–873. https://doi.org/10.1002/(SICI)1097-4598(200006)23:6

Article  PubMed  CAS  Google Scholar 

Kretschmer T, Antoniadis G, Braun V, Rath SA, Richter HP (2001) Evaluation of iatrogenic lesions in 722 surgically treated cases of peripheral nerve trauma. J Neurosurg 94(6):905–912. https://doi.org/10.3171/jns.2001.94.6.0905

Article  PubMed  CAS  Google Scholar 

Burke S, Shorten GD (2009) When pain after surgery doesn’t go away…. Biochem Soc Trans 37(1):318–322. https://doi.org/10.1042/BST0370318

Article  PubMed  CAS  Google Scholar 

Haanpää M, Attal N, Backonja M, Baron R, Bennett M, Bouhassira D, Cruccu G, Hansson P, Haythornthwaite JA, Iannetti GD, Jensen TS, Kauppila T, Nurmikko TJ, Rice ASC, Rowbotham M, Serra J, Sommer C, Smith BH, Treede R-D (2011) NeuPSIG guidelines on neuropathic pain assessment. Pain 152(1):14–27. https://doi.org/10.1016/j.pain.2010.07.031

Article  PubMed  Google Scholar 

Grinsell D, Keating CP (2014) Peripheral nerve reconstruction after injury: a review of clinical and experimental therapies. BioMed Res 2014:698256. https://doi.org/10.1155/2014/698256

Osborne NR, Anastakis DJ, Davis KD (2018Apr 1) Peripheral nerve injuries, pain, and neuroplasticity. J Hand Ther 31(2):184–194. https://doi.org/10.1016/j.jht.2018.01.011

Article  PubMed  Google Scholar 

Barth CW, Gibbs SL (2017) Direct administration of nerve-specific contrast to improve nerve sparing radical prostatectomy. Theranostics 7(3):573–593. https://doi.org/10.7150/thno.17433

Article  PubMed  PubMed Central  CAS  Google Scholar 

Walsh EM, Cole D, Tipirneni KE, Bland KI, Udayakumar N, Kasten BB, Bevans SL, McGrew BM, Kain JJ, Nguyen QT, Rosenthal EL, Warram JM (2019) Fluorescence imaging of nerves during surgery. Ann Surg 270(1):69–76. https://doi.org/10.1097/SLA.0000000000003130

Article  PubMed  Google Scholar 

Wang LG, Barth CW, Kitts CH, Mebrat MD, Montaño AR, House BJ, McCoy ME, Antaris AL, Galvis SN, McDowall I, Sorger JM, Gibbs SL (2020) Near-infrared nerve-binding fluorophores for buried nerve tissue imaging. Sci Transl Med 12(542):eaay0712. https://doi.org/10.1126/scitranslmed.aay0712.

Barth CW, Shah VM, Wang LG, Masillati AM, Al-Fatease A, Husain Rizvi SZ, Antaris AL, Sorger J, Rao DA, Alani AWG, Gibbs SL (2022May) A clinically relevant formulation for direct administration of nerve specific fluorophores to mitigate iatrogenic nerve injury. Biomaterials 1(284):121490. https://doi.org/10.1016/j.biomaterials.2022.121490

Article  CAS  Google Scholar 

Wang LG, Montaño AR, Masillati AM, Jones JA, Barth CW, Combs JR, Kumarapeli SU, Shams NA, van den Berg NS, Antaris AL, Galvis SN, McDowall I, Rizvi SZH, Alani AWG, Sorger JM, Gibbs SL (2024) Nerve Visualization using Phenoxazine-Based Near-Infrared Fluorophores to Guide Prostatectomy. Adv Mater 36(16):2304724. https://doi.org/10.1002/adma.202304724

Article  CAS  Google Scholar 

Lotan Y, Bivalacqua TJ, Downs T, Huang W, Jones J, Kamat AM, Konety B, Malmström P-U, McKiernan J, O’Donnell M, Patel S, Pohar K, Resnick M, Sankin A, Smith A, Steinberg G, Trabulsi E, Woods M, Daneshmand S (2019) Blue light flexible cystoscopy with hexaminolevulinate in non-muscle-invasive bladder cancer: review of the clinical evidence and consensus statement on optimal use in the USA - update 2018. Nat Rev Urol 16(6):377–386. https://doi.org/10.1038/s41585-019-0184-4

Article  PubMed  PubMed Central  Google Scholar 

Pogue BW, Rosenthal EL (2021) Review of successful pathways for regulatory approvals in open-field fluorescence-guided surgery. J Biomed Opt 26(3):030901. https://doi.org/10.1117/1.JBO.26.3.030901

Article  PubMed  PubMed Central  CAS  Google Scholar 

Van Keulen S, Hom M, White H, Rosenthal EL, Baik FM (2023) The evolution of fluorescence-guided surgery. Mol Imaging Biol 25(1):36–45. https://doi.org/10.1007/s11307-022-01772-8

Article  PubMed  CAS  Google Scholar 

Crawford KL, Pacheco FV, Lee Y-J, Hom M, Rosenthal EL, Nguyen QT, Orosco RK (2022) A scoping review of ongoing fluorescence-guided surgery clinical trials in otolaryngology. Laryngoscope 132(1):36–44. https://doi.org/10.1002/lary.29891

Article  PubMed  CAS  Google Scholar 

Bou-Samra P, Muhammad N, Chang A, Karsalia R, Azari F, Kennedy G, Stummer W, Tanyi J, Martin L, Vahrmeijer A, Smith B, Rosenthal E, Wagner P, Rice D, Lee A, Abdelhafeez H, Malek MM, Kohanbash G, Edwards WB, Henderson E, Skjøth-Rasmussen J, Orosco R, Gibbs S, Farnam RW, Shankar L, Sumer B, Kumar ATN, Marcu L, Li L, Greuv V, Delikatny EJ, Lee JYK, Singhal S (2023) Intraoperative molecular imaging: 3rd biennial clinical trials update. J Biomed Opt 28(5):050901. https://doi.org/10.1117/1.JBO.28.5.050901

Miampamba M, Liu J, Harootunian A, Gale AJ, Baird S, Chen SL, Nguyen QT, Tsien RY, González JE (2017) Sensitive in vivo visualization of breast cancer using ratiometric protease-activatable fluorescent imaging agent, AVB-620. Theranostics 7(13):3369–3386. https://doi.org/10.7150/thno.20678

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yamada M, Miller DM, Lowe M, Rowe C, Wood D, Soyer HP, Byrnes-Blake K, Parrish-Novak J, Ishak L, Olson JM, Brandt G, Griffin P, Spelman L, Prow TW (2021) A first-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and safety in skin cancer patients. Contemp Clin Trials Commun 23:100830. https://doi.org/10.1016/j.conctc.2021.100830

Moore TJ, Zhang H, Anderson G, Alexander GC (2018) Estimated costs of pivotal trials for novel therapeutic agents approved by the US Food and Drug Administration, 2015–2016. JAMA Intern Med 178(11):1451–1457. https://doi.org/10.1001/jamainternmed.2018.3931

Article  PubMed  PubMed Central  Google Scholar 

Wu C, Wei J, Tian D, Feng Y, Miller RH, Wang Y (2008) Molecular probes for imaging myelinated white matter in CNS. J Med Chem 51(21):6682–6688. https://doi.org/10.1021/jm8003637

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wang C, Popescu DC, Wu C, Zhu J, Macklin W, Wang Y (2010) In situ fluorescence imaging of myelination. J Histochem Cytochem 7:611–621. https://doi.org/10.1369/jhc.2010.954842

Article  CAS  Google Scholar 

Cotero VE, Siclovan T, Zhang R, Carter RL, Bajaj A, LaPlante NE, Kim E, Gray D, Staudinger VP, Yazdanfar S, Tan Hehir CA (2012) Intraoperative fluorescence imaging of peripheral and central nerves through a myelin-selective contrast agent. Mol Imaging Biol 14(6):708–717. https://doi.org/10.1007/s11307-012-0555-1

Article  PubMed  PubMed Central  Google Scholar 

Hingorani DV, Whitney MA, Friedman B, Kwon J-K, Crisp JL, Xiong Q, Gross L, Kane CJ, Tsien RY, Nguyen QT (2018) Nerve-targeted probes for fluorescence-guided intraoperative imaging. Theranostics 8(15):4226–4237. PMCID: PMC6096382. https://doi.org/10.7150/thno.23084

Barré-Sinoussi F, Montagutelli X (2015) Animal models are essential to biological research: issues and perspectives. Future Sci OA 1(4):FSO63. https://doi.org/10.4155/fso.15.63

Ruan Y, Robinson NB, Khan FM, Hameed I, Rahouma M, Naik A, Oakley CT, Rong L, Girardi LN, Gaudino M (2020) The translation of surgical animal models to human clinical research: A cross-sectional study. Int J Surg 77:25–29. https://doi.org/10.1016/j.ijsu.2020.03.023

Article  PubMed  Google Scholar 

Bateman LM, Hebert KA, Nunziata JA, Streeter SS, Barth CW, Wang LG, Gibbs SL, Henderson ER (2023) Preclinical evaluation of molecularly targeted fluorescent probes in perfused amputated human limbs. J Biomed Opt 28(8):082802. https://doi.org/10.1117/1.JBO.28.8.082802

Article  PubMed  PubMed Central  Google Scholar 

Corzo-León DE, Munro CA, MacCallum DM (2019) An ex vivo human skin model to study superficial fungal infections. Front Microbiol 10. https://doi.org/10.3389/fmicb.2019.01172

Garcia-Garcia FC, Candarlioglu PL, Porter JD, Davies DE, Swindle EJ, Morgan H (2022Dec) Microfluidic technologies for ex vivo tissue biopsies: A review. Organs-on-a-Chip 1(4):100020. https://doi.org/10.1016/j.ooc.2022.100020

Article  CAS  Google Scholar 

Cypel M, Yeung JC, Liu M, Anraku M, Chen F, Karolak W, Sato M, Laratta J, Azad S, Madonik M, Chow C-W, Chaparro C, Hutcheon M, Singer LG, Slutsky AS, Yasufuku K, de Perrot M, Pierre AF, Waddell TK, Keshavjee S (2011) Normothermic Ex Vivo Lung Perfusion in Clinical Lung Transplantation. N Engl J Med 364(15):1431–1440. https://doi.org/10.1056/NEJMoa1014597

Article  PubMed  CAS  Google Scholar 

Lam VWT, Laurence JM, Richardson AJ, Pleass HCC, Allen RDM (2013) Hypothermic machine perfusion in deceased donor kidney transplantation: a systematic review. J Surg Res 180(1):176–182. https://doi.org/10.1016/j.jss.2012.10.055

Article  PubMed  Google Scholar 

Elliott RM, Tintle SM, Levin LS (2014) Upper extremity transplantation: current concepts and challenges in an emerging field. Curr Rev Musculoskelet Med 7(1):83–88. https://doi.org/10.1007/s12178-013-9191-x

Article  PubMed  Google Scholar 

Werner NL, Alghanem F, Rakestraw SL, Sarver DC, Nicely B, Pietroski RE, Lange P, Rudich SM, Mendias CL, Rojas-Pena A, Magee JC, Bartlett RH, Ozer K (2017) Ex situ perfusion of human limb allografts for 24 hours. Transplantation. 101(3). Available from: https://journals.lww.com/transplantjournal/Fulltext/2017/03000/Ex_Situ_Perfusion_of_Human_Limb_Allografts_for_24.34.aspx

Rezaei M, Ordenana C, Figueroa BA, Said SA, Fahradyan V, Dalla Pozza E, Orfahli LM, Annunziata MJ, Rohde E, Madajka M, Papay F, Rampazzo A, Bassiri Gharb B (2022) Ex vivo normothermic perfusion of human upper limbs. Transplantation 106(8):1638–1646. https://doi.org/10.1097/TP.0000000000004045

Article  PubMed  CAS 

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