Marelli AJ, Mackie AS, Ionescu-Ittu R, Rahme E, Pilote L. Congenital heart disease in the general population: changing prevalence and age distribution. Circulation. 2007;115:163–72.

Article  PubMed  Google Scholar 

Murphy JG, Gersh BJ, Mair DD, Fuster V, McGoon MD, Ilstrup DM, et al. Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot. N Engl J Med. 1993;329:593–9.

Article  CAS  PubMed  Google Scholar 

Lee C, Lee CH, Kwak JG, Kim SH, Shim WS, Lee SY, et al. Factors associated with right ventricular dilatation and dysfunction in patients with chronic pulmonary regurgitation after repair of tetralogy of Fallot: analysis of magnetic resonance imaging data from 218 patients. J Thorac Cardiovasc Surg. 2014;148:2589–95.

Article  PubMed  Google Scholar 

Lopez L, Cohen MS, Anderson RH, Redington AN, Nykanen DG, Penny DJ, et al. Unnatural history of the right ventricle in patients with congenitally malformed hearts. Cardiol Young. 2010;20(Suppl 3):107–12.

Article  PubMed  Google Scholar 

Stout KK, Broberg CS, Book WM, Cecchin F, Chen JM, Dimopoulos K, et al. Chronic heart failure in congenital heart disease: a scientific statement from the American Heart Association. Circulation. 2016;133:770–801.

Article  PubMed  Google Scholar 

Walker LA, Buttrick PM. The right ventricle: biologic insights and response to disease: updated. Curr Cardiol Rev. 2013;9:73–81.

PubMed  PubMed Central  Google Scholar 

Greyson CR. Pathophysiology of right ventricular failure. Crit Care Med. 2008;36:S57-65.

Article  PubMed  Google Scholar 

Miyagawa S, Sawa Y, Taketani S, Kawaguchi N, Nakamura T, Matsuura N, Matsuda H. Myocardial regeneration therapy for heart failure: hepatocyte growth factor enhances the effect of cellular cardiomyoplasty. Circulation. 2002;105:2556–61.

Article  CAS  PubMed  Google Scholar 

Yoshida Y, Yamanaka S. iPS cells: a source of cardiac regeneration. J Mol Cell Cardiol. 2011;50:327–32.

Article  CAS  PubMed  Google Scholar 

Okano T, Yamada N, Sakai H, Sakurai Y. A novel recovery system for cultured cells using plasma-treated polystyrene dishes grafted with poly(N-isopropylacrylamide). J Biomed Mater Res. 1993;27:1243–51.

Article  CAS  PubMed  Google Scholar 

Miyagawa S, Sawa Y, Sakakida S, Taketani S, Kondoh H, Memon IA, et al. Tissue cardiomyoplasty using bioengineered contractile cardiomyocyte sheets to repair damaged myocardium: their integration with recipient myocardium. Transplantation. 2005;80:1586–95.

Article  CAS  PubMed  Google Scholar 

Kawamura M, Miyagawa S, Miki K, Saito A, Fukushima S, Higuchi T, et al. Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model. Circulation. 2012;126:S29-37.

Article  CAS  PubMed  Google Scholar 

LekanneDeprez RH, van den Hoff MJ, de Boer PA, Ruijter PM, Maas AA, Chamuleau RA, et al. Changing patterns of gene expression in the pulmonary trunk-banded rat heart. J Mol Cell Cardiol. 1998;30:1877–88.

Article  CAS  PubMed  Google Scholar 

Hoashi T, Matsumiya G, Miyagawa S, Ichikawa H, Ueno T, Ono M, et al. Skeletal myoblast sheet transplantation improves the diastolic function of a pressure-overloaded right heart. J Thorac Cardiovasc Surg. 2009;138:460–7.

Article  PubMed  Google Scholar 

Ishida M, Miyagawa S, Saito A, Fukushima S, Harada A, Ito E, et al. Transplantation of human-induced pluripotent stem cell-derived cardiomyocytes is superior to somatic stem cell therapy for restoring cardiac function and oxygen consumption in a porcine model of myocardial infarction. Transplantation. 2019;103:291–8.

Article  PubMed  PubMed Central  Google Scholar 

Kawamura M, Miyagawa S, Fukushima S, Saito A, Miki K, Funakoshi S, et al. Enhanced therapeutic effects of human iPS cell derived-cardiomyocyte by combined cell-sheets with omental flap technique in porcine ischemic cardiomyopathy model. Sci Rep. 2017;7:8824.

Article  PubMed  PubMed Central  Google Scholar 

Trip P, Rain S, Handoko ML, van der Bruggen CE, Bogaard HJ, Marcus JT, et al. Clinical relevance of right ventricular diastolic stiffness in pulmonary hypertension. Eur Respir J. 2015;45:1603–12.

Article  PubMed  Google Scholar 

Vonk Noordegraaf A, Westerhof BE, Westerhof N. The relationship between the right ventricle and its load in pulmonary hypertension. J Am Coll Cardiol. 2017;69:236–43.

Article  PubMed  Google Scholar 

Rain S, Handoko ML, Vonk Noordegraaf A, Bogaard HJ, van der Velden J, de Man FS. Pressure-overload-induced right heart failure. Pflugers Arch. 2014;466:1055–63.

CAS  PubMed  Google Scholar 

Hein S, Arnon E, Kostin S, Schönburg M, Elsässer A, Polyakova V, et al. Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms. Circulation. 2003;107:984–91.

Article  PubMed  Google Scholar 

van der Bruggen CEE, Tedford RJ, Handoko ML, van der Velden J, de Man FS. RV pressure overload: from hypertrophy to failure. Cardiovasc Res. 2017;113:1423–32.

Article  PubMed  Google Scholar 

Drake JI, Bogaard HJ, Mizuno S, Clifton B, Xie B, Gao Y, et al. Molecular signature of a right heart failure program in chronic severe pulmonary hypertension. Am J Respir Cell Mol Biol. 2011;45:1239–47.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ruiter G, Ying Wong Y, de Man FS, Louis Handoko M, Jaspers RT, Postmus PE, et al. Right ventricular oxygen supply parameters are decreased in human and experimental pulmonary hypertension. J Heart Lung Transplant. 2013;32:231–40.

Article  PubMed  Google Scholar 

van Wolferen SA, Marcus JT, Westerhof N, Spreeuwenberg MD, Marques KM, Bronzwaer JG, et al. Right coronary artery flow impairment in patients with pulmonary hypertension. Eur Heart J. 2008;29:120–7.

Article  PubMed  Google Scholar 

Gonzales C, Pedrazzini T. Progenitor cell therapy for heart disease. Exp Cell Res. 2009;315:3077–85.

Article  CAS  PubMed  Google Scholar 

Weber KT, Sun Y, Bhattacharya SK, Ahokas RA, Gerling IC. Myofibroblast-mediated mechanisms of pathological remodelling of the heart. Nat Rev Cardiol. 2013;10:15–26.

Article  CAS  PubMed  Google Scholar 

Burkhoff D, Mirsky I, Suga H. Assessment of systolic and diastolic ventricular properties via pressure-volume analysis: a guide for clinical, translational, and basic researchers. Am J Physiol Heart Circ Physiol. 2005;289:H501–12.

Article  CAS  PubMed  Google Scholar 

Marcus JT, Gan CT, Zwanenburg JJM, Boonstra A, Allaart CP, Götte MJW, Vonk-Noordegraaf A. Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling. J Am Coll Cardiol. 2008;51:750–7.

Article  PubMed  Google Scholar 

Gan CT-J, Holverda S, Marcus JT, Paulus WJ, Marques KM, Bronzwaer JGF, et al. Right ventricular diastolic dysfunction and the acute effects of sildenafil in pulmonary hypertension patients. Chest. 2007;132:11–7.

Article  CAS  PubMed  Google Scholar 

Higuchi T, Miyagawa S, Pearson JT, Fukushima S, Saito A, Tsuchimochi H, et al. Functional and electrical integration of induced pluripotent stem cell-derived cardiomyocytes in a myocardial infarction rat heart. Cell Transplant. 2015;24:2479–89.

Article  PubMed  Google Scholar 

Kawamura T, Miyagawa S, Fukushima S, Maeda A, Kashiyama N, Kawamura A, et al. Cardiomyocytes derived from MHC-homozygous induced pluripotent stem cells exhibit reduced allogeneic immunogenicity in MHC-matched non-human primates. Stem Cell Rep. 2016;6:312–20.

Article  CAS  Google Scholar 

Kainuma S, Miyagawa S, Fukushima S, Pearson J, Chen YC, Saito A, et al. Cell-sheet therapy with omentopexy promotes arteriogenesis and improves coronary circulation physiology in failing heart. Mol Ther. 2015;23:374–86.

Article  CAS  PubMed  PubMed Central