Strahl T, Thorner J (2007) Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochim Biophys Acta 1771(3):353–404

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sciorra VA, Audhya A, Parsons AB, Segev N, Boone C, Emr SD (2005) Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. Mol Biol Cell 16(2):776–793

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yakir-Tamang L, Gerst JE (2009) A phosphatidylinositol-transfer protein and phosphatidylinositol-4-phosphate 5-kinase control Cdc42 to regulate the actin cytoskeleton and secretory pathway in yeast. Mol Biol Cell 20(15):3583–3597

Article  PubMed  PubMed Central  CAS  Google Scholar 

Schekman R (2010) Charting the secretory pathway in a simple eukaryote. Mol Biol Cell 21(22):3781–3784

Article  PubMed  PubMed Central  CAS  Google Scholar 

Henry SA, Kohlwein SD, Carman GM (2012) Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics 190(2):317–349

Article  PubMed  PubMed Central  CAS  Google Scholar 

Singh P (2017) Budding yeast: an ideal backdrop for in vivo lipid biochemistry. Front Cell Dev Biol 4:156

Article  PubMed  PubMed Central  Google Scholar 

Guan XL, Riezman I, Wenk MR, Riezman H (2010) Yeast lipid analysis and quantification by mass spectrometry. Methods Enzymol 470:369–391

Article  PubMed  CAS  Google Scholar 

Hammond GR, Balla T (2015) Polyphosphoinositide binding domains: key to inositol lipid biology. Biochim Biophys Acta 1851(6):746–758

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ganesan S, Shabits BN, Zaremberg V (2016) Tracking diacylglycerol and phosphatidic acid pools in budding yeast. Lipid Insights 8(Suppl 1):75–85

PubMed  PubMed Central  Google Scholar 

Hammond GRV, Ricci MMC, Weckerly CC, Wills RC (2022) An update on genetically encoded lipid biosensors. Mol Biol Cell. https://doi.org/10.1091/mbc.E21-07-0363

Article  PubMed  PubMed Central  Google Scholar 

Steinfeld N, Giridharan SSP, Kauffman EJ, Weisman LS (2021) Simultaneous detection of phosphoinositide lipids by radioactive metabolic labeling. Methods Mol Biol 2251:1–17

Article  PubMed  PubMed Central  CAS  Google Scholar 

Audhya A, Foti M, Emr SD (2000) Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics. Mol Biol Cell 11(8):2673–2689

Article  PubMed  PubMed Central  CAS  Google Scholar 

Han GS, Audhya A, Markley DJ, Emr SD, Carman GM (2002) The Saccharomyces cerevisiae LSB6 gene encodes phosphatidylinositol 4-kinase activity. J Biol Chem 277(49):47709–47718

Article  PubMed  CAS  Google Scholar 

Chang FS, Han GS, Carman GM, Blumer KJ (2005) A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility. J Cell Biol 171(1):133–142

Article  PubMed  PubMed Central  CAS  Google Scholar 

Kourkoulou A, Martzoukou O, Fischer R, Amillis S (2024) A type II phosphatidylinositol-4-kinase coordinates sorting of cargo polarizing by endocytic recycling. Commun Biol 7(1):855

Article  PubMed  PubMed Central  CAS  Google Scholar 

Heckle LA, Kozminski KG (2023) Osh-dependent and -independent regulation of PI4P levels during polarized growth of saccharomyces cerevisiae. Mol Biol Cell 34(11):ar104

Article  PubMed  PubMed Central  CAS  Google Scholar 

Mizuno-Yamasaki E, Rivera-Molina F, Novick P (2012) GTPase networks in membrane traffic. Annu Rev Biochem 81:637–659

Article  PubMed  PubMed Central  CAS  Google Scholar 

Stefan CJ, Audhya A, Emr SD (2002) The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate. Mol Biol Cell 13:542–557

Article  PubMed  PubMed Central  CAS  Google Scholar 

Baird D, Stefan C, Audhya A, Weys S, Emr SD (2008) Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3. J Cell Biol 183(6):1061–1074

Article  PubMed  PubMed Central  CAS  Google Scholar 

Omnus DJ, Cadou A, Thomas FB, Bader JM, Soh N, Chung GHC, Vaughan AN, Stefan CJ (2020) A heat-sensitive Osh protein controls PI4P polarity. BMC Biol 18(1):28

Article  PubMed  PubMed Central  CAS  Google Scholar 

Foti M, Audhya A, Emr SD (2001) Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology. Mol Biol Cell 12(8):2396–2411

Article  PubMed  PubMed Central  CAS  Google Scholar 

Del Bel LM, Brill JA (2018) Sac1, a lipid phosphatase at the interface of vesicular and nonvesicular transport. Traffic 19(5):301–318

Article  PubMed  Google Scholar 

Stefan CJ, Manford AG, Baird D, Yamada-Hanff J, Mao Y, Emr SD (2011) Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites. Cell 144(3):389–401

Article  PubMed  CAS  Google Scholar 

Quon E, Sere YY, Chauhan N, Johansen J, Sullivan DP, Dittman JS, Rice WJ, Chan RB, Di Paolo G, Beh CT, Menon AK (2018) Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation. PLoS Biol 16(5):e2003864

Article  PubMed  PubMed Central  Google Scholar 

Nenadic A, Zaman MF, Johansen J, Volpiana MW, Beh CT (2023) Increased phospholipid flux bypasses overlapping essential requirements for the yeast Sac1p phosphoinositide phosphatase and ER-PM membrane contact sites. J Biol Chem 299(9):105092

Article  PubMed  PubMed Central  CAS  Google Scholar 

Guo S, Stolz LE, Lemrow SM, York JD (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990–12995

Article  PubMed  CAS  Google Scholar 

Garrenton LS, Stefan CJ, McMurray MA, Emr SD, Thorner J (2010) Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling. Proc Natl Acad Sci USA 107(26):11805–11810

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wedlich-Soldner R, Altschuler S, Wu L, Li R (2003) Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase. Science 299(5610):1231–1235

Article  PubMed  CAS  Google Scholar 

Desrivières S, Cooke FT, Parker PJ, Hall MN (1998) MSS4, a phosphatidylinositol-4-phosphate 5- kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae. J Biol Chem 273(25):15787–15793