Gerstein AS. Nucleotides, oligonucleotides, and polynucleotides. In Molecular Biology Problem Solver, Gerstein AS, editor. 2001. https://doi.org/10.1002/0471223905.ch10.

Tang SL, Smith RL, Poliakoff M. Principles of green chemistry: PRODUCTIVELY. Green Chem. 2005;7:761–2.

Article  Google Scholar 

Koel M, Kaljurand M. Application of the principles of green chemistry in analytical chemistry. Pure Appl Chem. 2006;78:1993–2002. https://doi.org/10.1351/pac200678111993.

Article  CAS  Google Scholar 

Ivanković A, Dronjić A, Bevanda AM, Talić S. Review of 12 principles of green chemistry in practice. Int J Sustain Green Energy. 2017;6:39–48. https://doi.org/10.11648/j.ijrse.20170603.12.

Article  CAS  Google Scholar 

Gallo M, Montserrat JM, Iribarren A. Design and applications of modified oligonucleotides. Braz J Med Biol Res. 2003;36:143–51.

Article  CAS  PubMed  Google Scholar 

Lonnberg H. Solid-phase synthesis of oligonucleotide conjugates useful for delivery and targeting of potential nucleic acid therapeutics. Bioconjug Chem. 2009;20:1065–94.

Article  CAS  PubMed  Google Scholar 

Lönnberg H. Synthesis of oligonucleotides on a soluble support. Beilstein J Org Chem. 2017;13:1368–87.

Article  PubMed  PubMed Central  Google Scholar 

Bielinska A, Shivdasani RA, Zhang L, Nabel GJ. Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science. 1990;250:997–1000.

Article  CAS  PubMed  Google Scholar 

Hendling M, Barišić I. In-silico design of DNA oligonucleotides: challenges and approaches. Comput Struct Biotechnol J. 2019;17:1056–65. https://doi.org/10.1016/j.csbj.2019.07.008.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Remmers EF, Ombrello MJ, Siegel RM. 12—Principles and techniques in molecular biology. In: Hochberg MC, et al., editors. Rheumatology. 6th ed. Philadelphia: Mosby; 2015. pp. 86–98.

Shendure J, Balasubramanian S, Church GM, Gilbert W, Rogers J, Schloss JA, et al. DNA sequencing at 40: past, present and future. Nature. 2017;550:345–53. https://doi.org/10.1038/nature24286.

Article  CAS  PubMed  Google Scholar 

Ashwini M, Murugan SB, Balamurugan S, Sathishkumar R. Advances in molecular cloning. Mol Biol 2016;50:1–6. https://doi.org/10.1134/S0026893316010131.

Article  CAS  Google Scholar 

Loy A, Horn M, Wagner M. probeBase: an online resource for rRNA-targeted oligonucleotide probes. Nucleic Acids Res. 2003;31:514–6. https://doi.org/10.1093/nar/gkg016.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qureshi A, Thakur N, Monga I, Thakur A, Kumar M. VIRmiRNA: a comprehensive resource for experimentally validated viral miRNAs and their targets. Database. 2014;2014:bau103.

Article  PubMed  PubMed Central  Google Scholar 

Langner HK, Jastrzebska K, Caruthers MH. Synthesis and characterization of thiophosphoramidate morpholino oligonucleotides and chimeras. J Am Chem Soc. 2020;142:16240–53.

Article  CAS  PubMed  Google Scholar 

Monga I, Qureshi A, Thakur N, Gupta AK, Kumar M. ASPsiRNA: a resource of ASP-siRNAs having therapeutic potential for human genetic disorders and algorithm for prediction of their inhibitory efficacy. G3 Genes Genomes Genet. 2017;7:2931–43.

Article  CAS  Google Scholar 

de la Torre BG, Albericio F. The pharmaceutical industry in 2023: an analysis of FDA drug approvals from the perspective of molecules. Molecules. 2024;29. https://doi.org/10.3390/molecules29030585.

Al Shaer D, Al Musaimi O, Albericio F, de la Torre BG. 2023 FDA TIDES (peptides and oligonucleotides) harvest. Pharmaceuticals. 2024;17:243. https://doi.org/10.3390/ph17020243.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Angrish N, Khare G. Antisense oligonucleotide based therapeutics and its applications against bacterial infections. Med Drug Discov. 2023;20:100166. https://doi.org/10.1016/j.medidd.2023.100166.

Article  CAS  Google Scholar 

Buthelezi LA, Pillay S, Ntuli NN, Gcanga L, Guler R. Antisense therapy for infectious diseases. Cells. 2023;12. https://doi.org/10.3390/cells12162119.

Moumné L, Marie A-C, Crouvezier N. Oligonucleotide therapeutics: from discovery and development to patentability. Pharmaceutics. 2022;14:260.

Article  PubMed  PubMed Central  Google Scholar 

Al Shaer D, Al Musaimi O, Albericio F, de la Torre BG. 2019 FDA TIDES (peptides and oligonucleotides) harvest. Pharmaceuticals. 2020;13. https://doi.org/10.3390/ph13030040.

Al Musaimi O, Al Shaer D, Albericio F, de la Torre BG. 2020 FDA TIDES (peptides and oligonucleotides) harvest. Pharmaceuticals. 2021;14:145. https://doi.org/10.3390/ph14020145.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Al Shaer D, Al Musaimi O, Albericio F, de la Torre BG. 2018 FDA tides harvest. Pharmaceuticals. 2019;12:52. https://doi.org/10.3390/ph12020052.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thakur S, Sinhari A, Jain P, Jadhav HR. A perspective on oligonucleotide therapy: approaches to patient customization. Front Pharmacol 2022;13:1006304. https://doi.org/10.3389/fphar.2022.1006304.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Al Shaer D, Al Musaimi O, Albericio F, de la Torre BG. 2021 FDA TIDES (peptides and oligonucleotides) harvest. Pharmaceuticals. 2022;15:222.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Al Musaimi O, Al Shaer D, Albericio F, de la Torre BG. 2022 FDA TIDES (peptides and oligonucleotides) harvest. Pharmaceuticals. 2023;16:336.

Article  PubMed  PubMed Central  Google Scholar 

Wang L, Wang N, Zhang W, Cheng X, Yan Z, Shao G, et al. Therapeutic peptides: current applications and future directions. Signal Transduct Target Ther. 2022;7:48.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Igarashi J, Niwa Y, Sugiyama D. Research and development of oligonucleotide therapeutics in Japan for rare diseases. Future Rare Dis. 2022;2:FRD19.

Article  CAS  Google Scholar 

Michelson AM, Todd AR. Nucleotides part XXXII. Synthesis of a dithymidine dinucleotide containing a 3′: 5′-internucleotidic linkage. J Chem Soc (Resumed). 1955;(0):2632–2638.

Lane AN, Fan TW. Regulation of mammalian nucleotide metabolism and biosynthesis. Nucleic Acids Res. 2015;43:2466–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schaller H, Weimann G, Lerch B, Khorana H. Studies on polynucleotides. XXIV. 1 The stepwise synthesis of specific deoxyribopolynucleotides (4). 2 Protected derivatives of deoxyribonucleosides and new syntheses of deoxyribonucleoside-3″ phosphates 3. J Am Chem Soc. 1963;85:3821–7.

Article  CAS  Google Scholar 

Khorana H, Razzell W, Gilham P, Tener G, Pol E. Syntheses of dideoxyribonucleotides. J Am Chem Soc. 1957;79:1002–3.

Article  CAS  Google Scholar 

Gilham PT, Khorana HG. Studies on polynucleotides. I. A new and general method for the chemical synthesis of the C5″-C3″ internucleotidic linkage. Syntheses of deoxyribo-dinucleotides1. J Am Chem Soc. 1958;80:6212–22.

Article  CAS  Google Scholar 

Letsinger RL, Mahadevan V. Oligonucleotide synthesis on a polymer support1, 2. J Am Chem Soc. 1965;87:3526–7.

Article  CAS  PubMed  Google Scholar 

Letsinger RL, Ogilvie KK. Convenient method for stepwise synthesis of oligothymidylate derivatives in large-scale quantities. J Am Chem Soc. 1967;89:4801–3.

Article  CAS