Abd Wahab NA, Lajis NH, Abas F, Othman I, Naidu R (2020) Mechanism of Anti-Cancer Activity of Curcumin on Androgen-Dependent and Androgen-Independent Prostate Cancer. Nutrients 12(3):679. https://doi.org/10.3390/nu12030679

Article  PubMed  PubMed Central  Google Scholar 

Adamus A, Ali I, Vasileiadis V, Al-Hileh L, Lisec J, Frank M, Seitz G, Engel N (2021) Vincetoxicum arnottianum modulates motility features and metastatic marker expression in pediatric rhabdomyosarcoma by stabilizing the actin cytoskeleton. BMC Complement Med Ther 21(1):136. https://doi.org/10.1186/s12906-021-03299-x

Article  PubMed  PubMed Central  Google Scholar 

Ahmad A, Tiwari RK, Saeed M, Ahmad I, Ansari IA (2022) Glycyrrhizin Mediates Downregulation of Notch Pathway Resulting in Initiation of Apoptosis and Disruption in the Cell Cycle Progression in Cervical Cancer Cells. Nutr Cancer 74(2):622–639. https://doi.org/10.1080/01635581.2021.1895234

Article  PubMed  Google Scholar 

Alatawi FS, Faridi U (2023) Anticancer and anti-metastasis activity of 1,25 dihydroxycholecalciferols and genistein in MCF-7 and MDA-MB-231 breast cancer cell lines. Heliyon 9(11):e21975. https://doi.org/10.1016/j.heliyon.2023.e21975

Article  PubMed  PubMed Central  Google Scholar 

Alehagen U, Opstad TB, Alexander J, Larsson A, Aaseth J (2021) Impact of Selenium on Biomarkers and Clinical Aspects Related to Ageing A Review. Biomol 11(10):1478. https://doi.org/10.3390/biom11101478

Article  Google Scholar 

Alorda-Clara M, Torrens-Mas M, Morla-Barcelo PM, Roca P, Sastre-Serra J, Pons DG, Oliver J (2022) High Concentrations of Genistein Decrease Cell Viability Depending on Oxidative Stress and Inflammation in Colon Cancer Cell Lines. Int J Mol Sci 23(14):7526. https://doi.org/10.3390/ijms23147526

Article  PubMed  PubMed Central  Google Scholar 

Al-Thamiree Mezban S, Fox SW (2023) Genistein and coumestrol reduce MCF-7 breast cancer cell viability and inhibit markers of preferential metastasis, bone matrix attachment and tumor-induced osteoclastogenesis. Arch Biochem Biophys 740:109583. https://doi.org/10.1016/j.abb.2023.109583

Article  PubMed  Google Scholar 

Bachmann M, Li W, Edwards MJ, Ahmad SA, Patel S, Szabo I, Gulbins E (2020) Voltage-Gated Potassium Channels as Regulators of Cell Death. Front Cell Dev Biol 8:611853. https://doi.org/10.3389/fcell.2020.611853

Article  PubMed  PubMed Central  Google Scholar 

Bai HL, Kang CM, Sun ZQ, Li XH, Dai XY, Huang RY, Zhao JJ, Bei YR, Huang XZ, Lu ZF, Wu SG, Lu JB, Ping BH, Wang Q, Hu YW (2020) TTDA inhibited apoptosis by regulating the p53-Bax/Bcl2 axis in glioma. Exp Neurol 331:113380. https://doi.org/10.1016/j.expneurol.2020.113380

Article  PubMed  Google Scholar 

Banyś K, Stawarska A, Wyrębiak R et al (2022) The Effect of Genistein Supplementation on Cholesterol Oxidation Products and Fatty Acid Profiles in Serums of Rats with Breast Cancer. Foods 11(4):605

Article  PubMed  PubMed Central  Google Scholar 

Basu A (2022) The interplay between apoptosis and cellular senescence: Bcl-2 family proteins as targets for cancer therapy. Pharmacol Ther 230:107943. https://doi.org/10.1016/j.pharmthera.2021.107943

Article  PubMed  Google Scholar 

Basu P, Maier C (2018) Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives. Biomed Pharmacother 107:1648–1666. https://doi.org/10.1016/j.biopha.2018.08.100

Article  PubMed  Google Scholar 

Bensaada S, Peruzzi G, Cubizolles L, Denayrolles M, Bennetau-Pelissero C (2024) Traditional and Domestic Cooking Dramatically Reduce Estrogenic Isoflavones in Soy Foods. Foods 13(7):999. https://doi.org/10.3390/foods13070999

Article  PubMed  PubMed Central  Google Scholar 

Bhardwaj JK, Siwach A, Sachdeva SN (2024) Metabolomics and cellular altered pathways in cancer biology: A review. J Biochem Mol Toxicol 38(9):e23807. https://doi.org/10.1002/jbt.23807

Article  PubMed  Google Scholar 

Bhat SS, Prasad SK, Shivamallu C et al (2021a) Genistein: A potent anti-breast cancer agent. Curr Issues Mol Biol 43:1502–1517

Article  PubMed  PubMed Central  Google Scholar 

Bhat SS, Prasad SK, Shivamallu C, Prasad KS, Syed A, Reddy P, Cull CA, Amachawadi RG (2021b) Genistein: A Potent Anti-Breast Cancer Agent. Curr Issues Mol Biol 43(3):1502–1517. https://doi.org/10.3390/cimb43030106

Article  PubMed  PubMed Central  Google Scholar 

Boonyong C, Vardhanabhuti N, Jianmongkol S (2020) Natural polyphenols prevent indomethacin-induced and diclofenac-induced Caco-2 cell death by reducing endoplasmic reticulum stress regardless of their direct reactive oxygen species scavenging capacity. J Pharm Pharmacol 72(4):583–591. https://doi.org/10.1111/jphp.13227

Article  PubMed  Google Scholar 

Bosviel R, Dumollard E, Déchelotte P et al (2012) Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer? Omi A J Integr Biol 16:235–244

Article  Google Scholar 

Boutas I, Kontogeorgi A, Dimitrakakis C et al (2022) Soy Isoflavones and Breast Cancer Risk: A Meta-analysis. In Vivo (Brooklyn) 36:556–562

Article  Google Scholar 

Brinkman JA, Liu Y, Kron SJ (2021) Small-molecule drug repurposing to target DNA damage repair and response pathways. Semin Cancer Biol 68:230–241. https://doi.org/10.1016/j.semcancer.2020.02.013

Article  PubMed  Google Scholar 

Bruno S, Luserna G, di Rorà A, Napolitano R, Soverini S, Martinelli G, Simonetti G (2022) CDC20 in and out of mitosis: a prognostic factor and therapeutic target in hematological malignancies. J Exp Clin Cancer Res: CR 41(1):159. https://doi.org/10.1186/s13046-022-02363-9

Article  PubMed  PubMed Central  Google Scholar 

Çal Doğan T, Aydın Dilsiz S, Canpınar H, Ündeğer Bucurgat Ü (2024) Genistein Enhances TRAIL-Mediated Apoptosis Through the Inhibition of XIAP and DcR1 in Colon Carcinoma Cells Treated with 5-Fluorouracil. Turkish J Pharm Sci 21(1):7–24. https://doi.org/10.4274/tjps.galenos.2023.60543

Article  Google Scholar 

Carrera AN, Grant MKO, Zordoky BN (2020) CYP1B1 as a therapeutic target in cardio-oncology. Clinical Science (London) 134(21):2897–2927. https://doi.org/10.1042/CS20200310

Article  Google Scholar 

Carrié L, Virazels M, Dufau C, Montfort A, Levade T, Ségui B, Andrieu-Abadie N (2020) New Insights into the Role of Sphingolipid Metabolism in Melanoma. Cells 9(9):1967. https://doi.org/10.3390/cells9091967

Article  PubMed  PubMed Central  Google Scholar 

Chaichian S, Nikfar B, Bidgoli SA, Moazzami B (2023) The Role of Genistein and its Derivatives in Ovarian Cancer: New Perspectives for Molecular Mechanisms and Clinical Applications. Curr Med Chem. https://doi.org/10.2174/0109298673251713231019091910

Article  PubMed  Google Scholar 

Chen FP, Chien MH (2014) Phytoestrogens induce apoptosis through a mitochondria/caspase pathway in human breast cancer cells. Climacteric 17:385–392

Article  PubMed  Google Scholar 

Chen J, Lin C, Yong W et al (2015a) Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-akt signaling pathway in human breast cancer MCF-7 cells. Cell Physiol Biochem 35:722–728

Article  PubMed  Google Scholar 

Chen J, Duan Y, Zhang X et al (2015b) Genistein induces apoptosis by the inactivation of the IGF-1R/p-Akt signaling pathway in MCF-7 human breast cancer cells. Food Funct 6:995–1000

Article  PubMed  Google Scholar 

Chen C, Wang Y, Chen S, Ruan X, Liao H, Zhang Y, Sun J, Gao J, Deng G (2020) Genistein inhibits migration and invasion of cervical cancer HeLa cells by regulating FAK-paxillin and MAPK signaling pathways. Taiwan J Obstet Gynecol 59(3):403–408. https://doi.org/10.1016/j.tjog.2020.03.012

Article  PubMed  Google Scholar 

Chen M, Li S, Srinivasasainagendra V et al (2022a) Maternal soybean genistein on prevention of later-life breast cancer through inherited epigenetic regulations. Carcinogenesis 43:190–202

Article  PubMed  PubMed Central  Google Scholar 

Chen M, Li S, Srinivasasainagendra V, Sharma M, Li Z, Tiwari H, Tollefsbol TO, Li Y (2022b) Maternal soybean genistein on prevention of later-life breast cancer through inherited epigenetic regulations. Carcinogenesis 43(3):190–202. https://doi.org/10.1093/carcin/bgac009

Article  PubMed  PubMed Central  Google Scholar