Luteolin Protects against Vascular Calcification by Modulating SIRT1/CXCR4 Signaling Pathway and Promoting Autophagy

Hecht HS. Coronary artery calcium scanning: past, present, and future. J Am Coll Cardiol Img. 2015;8(5):579–96.

Article  Google Scholar 

Ruan Y, Guo Y, Zheng Y, Huang Z, Sun S, Kowal P, et al. Cardiovascular disease (CVD) and associated risk factors among older adults in six low-and middle-income countries: results from SAGE wave 1. BMC Public Health. 2018;18(1):778.

Article  PubMed  PubMed Central  Google Scholar 

Lee SJ, Lee IK, Jeon JH. Vascular calcification-new insights into its mechanism. Int J Mol Sci. 2020;21(8)

Fatokun AA, Tome M, Smith RA, Darlington LG, Stone TW. Protection by the flavonoids quercetin and luteolin against peroxide- or menadione-induced oxidative stress in MC3T3-E1 osteoblast cells. Nat Prod Res. 2015;29(12):1127–32.

Article  CAS  PubMed  Google Scholar 

Xia F, Wang C, Jin Y, Liu Q, Meng Q, Liu K, et al. Luteolin protects HUVECs from TNF-α-induced oxidative stress and inflammation via its effects on the Nox4/ROS-NF-κB and MAPK pathways. J Atheroscler Thromb. 2014;21(8):768–83.

Article  PubMed  Google Scholar 

Jing Z, Wang C, Yang Q, Wei X, Jin Y, Meng Q, et al. Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro. J Cell Physiol. 2019;234(4):4472–90.

Article  CAS  PubMed  Google Scholar 

Shao JS, Cai J, Towler DA. Molecular mechanisms of vascular calcification: lessons learned from the aorta. Arterioscler Thromb Vasc Biol. 2006;26(7):1423–30.

Article  CAS  PubMed  Google Scholar 

Gauthier J, Vincent AT, Charette SJ, Derome N. A brief history of bioinformatics. Brief Bioinform. 2019;20(6):1981–96.

Article  PubMed  Google Scholar 

Li F, You Y, Zhu H. 15-HETE protects pulmonary artery smooth muscle cells against apoptosis via SIRT1 regulation during hypoxia. Biomed Pharmacother. 2018;108:325–30.

Article  CAS  PubMed  Google Scholar 

Bartoli-Leonard F, Wilkinson FL, Schiro A, Inglott FS, Alexander MY, Weston R. Suppression of SIRT1 in diabetic conditions induces osteogenic differentiation of human vascular smooth muscle cells via RUNX2 Signalling. Sci Rep. 2019;9(1):878.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bartoli-Leonard F, Wilkinson FL, Schiro A, Serracino Inglott F, Alexander MY, Weston R. Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification. Cardiovasc Res. 2021;117(3):836–49.

Article  CAS  PubMed  Google Scholar 

Qiao L, Shao J. SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex. J Biol Chem. 2006;281(52):39915–24.

Article  CAS  PubMed  Google Scholar 

Zhao L, Zhou Z, Zhu C, Fu Z, Yu D. Luteolin alleviates myocardial ischemia reperfusion injury in rats via Siti1/NLRP3/NF-κB pathway. Int Immunopharmacol. 2020;85:106680.

Article  CAS  PubMed  Google Scholar 

Scherz-Shouval R, Elazar Z. ROS, mitochondria and the regulation of autophagy. Trends Cell Biol. 2007;17(9):422–7.

Article  CAS  PubMed  Google Scholar 

Cahill PA, Redmond EM. Vascular endothelium - gatekeeper of vessel health. Atherosclerosis. 2016;248:97–109.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dai XY, Zhao MM, Cai Y, Guan QC, Zhao Y, Guan Y, et al. Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release. Kidney Int. 2013;83(6):1042–51.

Article  CAS  PubMed  Google Scholar 

Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, et al. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci USA. 2008;105(9):3374–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang R, Xu Y, Wan W, Shou X, Qian J, You Z, et al. Deacetylation of nuclear LC3 drives autophagy initiation under starvation. Mol Cell. 2015;57(3):456–66.

Article  CAS  PubMed  Google Scholar 

Hariharan N, Maejima Y, Nakae J, Paik J, Depinho RA, Sadoshima J. Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes. Circ Res. 2010;107(12):1470–82.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deng Z, Sun M, Wu J, Fang H, Cai S, An S, et al. SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation. Cell Death Dis. 2021;12(2):217.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Munafó DB, Colombo MI. A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. J Cell Sci. 2001;114(Pt 20):3619–29.

Article  PubMed  Google Scholar 

Ye F, Song J, Wang Y, Xu X, Zhang K. Proliferation potential-related protein promotes the esophageal Cancer cell proliferation, migration and suppresses apoptosis by mediating the expression of p53 and Interleukin-17. Pathobiology. 2018;85(5–6):322–31.

Article  PubMed  Google Scholar 

Fowler EK, Mohorianu I, Smith DT, Dalmay T, Chapman T. Small RNA populations revealed by blocking rRNA fragments in Drosophila melanogaster reproductive tissues. PLoS One. 2018;13(2):e0191966.

Article  PubMed  PubMed Central  Google Scholar 

Raj S, Sasidharan S, Dubey VK, Saudagar P. Identification of lead molecules against potential drug target protein MAPK4 from L. donovani: An in-silico approach using docking, molecular dynamics and binding free energy calculation. PLoS One. 2019;14(8):e0221331.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Trott O, Olson AJ. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem. 2010;31(2):455–61.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang Z, Wu Z, Ma B, Yu L, He Y, Xu D, et al. Enhanced in vitro biocompatibility and osteogenesis of titanium substrates immobilized with dopamine-assisted superparamagnetic Fe(3)O(4) nanoparticles for hBMSCs. R Soc Open Sci. 2018;5(8):172033.

Article  PubMed  PubMed Central  Google Scholar 

Sun WL, Wang N, Xu Y. Impact of miR-302b on calcium-phosphorus metabolism and vascular calcification of rats with chronic renal failure by regulating BMP-2/Runx2/Osterix signaling pathway. Arch Med Res. 2018;49(3):164–71.

Article  CAS  PubMed  Google Scholar 

Gao M, Chen T, Wu L, Zhao X, Mao H, Xing C. Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β-catenin signaling pathway. Mol Med Rep. 2017;16(5):6208–13.

Article  CAS  PubMed  Google Scholar 

Jeon KI, Phipps RP, Sime PJ, Huxlin KR. Inhibitory effects of PPARγ ligands on TGF-β1-induced CTGF expression in cat corneal fibroblasts. Exp Eye Res. 2015;138:52–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee CY, Su CH, Tsai PK, Yang ML, Ho YC, Lee SS, et al. Cadmium nitrate-induced neuronal apoptosis is protected by N-acetyl-l-cysteine via reducing reactive oxygen species generation and mitochondria dysfunction. Biomed Pharmacother. 2018;108:448–56.

Article  CAS  PubMed  Google Scholar 

Mao Z, Wang P, Pan Q, Huang X, Zhang R, Shang X, et al. Pravastatin alleviates interleukin 1β-induced cartilage degradation by restoring impaired autophagy associated with MAPK pathway inhibition. Int Immunopharmacol. 2018;64:308–18.

Article  CAS  PubMed

留言 (0)

沒有登入
gif