Li, D. P., Han, Y. X., He, Y. S., Wen, Y., Liu, Y. C., Fu, Z. Y., Pan, H. F., & Cao, F. (2023). A global assessment of incidence trends of autoimmune diseases from 1990 to 2019 and predicted changes to 2040. Autoimmunity Reviews, 22(10), 103407

Article  Google Scholar 

Wylezinski, L. S., Gray, J. D., Polk, J. B., Harmata, A. J., & Spurlock, C. F. (2019). Illuminating an invisible epidemic: A systemic review of the clinical and economic benefits of early diagnosis and treatment in inflammatory disease and related syndromes. Journal of Clinical Medicine, 8(4), 493

Article  Google Scholar 

Raphael, I., Nalawade, S., Eagar, T. N., & Forsthuber, T. G. (2015). T cell subsets and their signature cytokines in autoimmune and inflammatory diseases. Cytokine, 74(1), 5–17

Article  Google Scholar 

Hofmann, S. R., Rösen-Wolff, A., Tsokos, G. C., & Hedrich, C. M. (2012). Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury. Clinical Immunology, 143(2), 116–127

Article  Google Scholar 

Rutz, S., Wang, X., & Ouyang, W. (2014). The IL-20 subfamily of cytokines–from host defence to tissue homeostasis. Nature Reviews. Immunology, 14(12), 783–795

Article  Google Scholar 

Van Belle, A. B., Cochez, P. M., de Heusch, M., Pointner, L., Opsomer, R., Raynaud, P., Achouri, Y., Hendrickx, E., Cheou, P., Warnier, G., Renauld, J. C., Baeck, M., & Dumoutier, L. (2019). IL-24 contributes to skin inflammation in Para-Phenylenediamine-induced contact hypersensitivity. Scientific Reports, 9(1), 1852

Article  Google Scholar 

Chen, J., Caspi, R. R., & Chong, W. P. (2018). IL-20 receptor cytokines in autoimmune diseases. Journal of Leukocyte Biology, 104(5), 953–959

Article  Google Scholar 

Persaud, L., De Jesus, D., Brannigan, O., Richiez-Paredes, M., Huaman, J., Alvarado, G., Riker, L., Mendez, G., Dejoie, J., & Sauane, M. (2016). Mechanism of action and applications of interleukin 24 in immunotherapy. International Journal of MolecularSciences, 17(6), 869

Google Scholar 

Huang, E. Y., Madireddi, M. T., Gopalkrishnan, R. V., Leszczyniecka, M., Su, Z., Lebedeva, I. V., Kang, D., Jiang, H., Lin, J. J., Alexandre, D., Chen, Y., Vozhilla, N., Mei, M. X., Christiansen, K. A., Sivo, F., Goldstein, N. I., Mhashilkar, A. B., Chada, S., Huberman, E., Pestka, S., & Fisher, P. B. (2001). Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties. Oncogene, 20(48), 7051–7063

Article  Google Scholar 

Jiang, H., Lin, J. J., Su, Z. Z., Goldstein, N. I., & Fisher, P. B. (1995). Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene, 11(12), 2477–2486

Google Scholar 

Feng, K., Cen, J., Zou, X., & Zhang, T. (2024). Novel insight into MDA-7/IL-24: A potent therapeutic target for autoimmune and inflammatory diseases. Clinical Immunology, 266, 110322

Article  Google Scholar 

Wang, M., Tan, Z., Zhang, R., Kotenko, S. V., & Liang, P. (2002). Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. The Journal of Biological Chemistry, 277(9), 7341–7347

Article  Google Scholar 

Fuson, K. L., Zheng, M., Craxton, M., Pataer, A., Ramesh, R., Chada, S., & Sutton, R. B. (2009). Structural mapping of post-translational modifications in human interleukin-24: Role of N-linked glycosylation and disulfide bonds in secretion and activity. The Journal of Biological Chemistry, 284(44), 30526–30533

Article  Google Scholar 

Allen, M., Pratscher, B., Roka, F., Krepler, C., Wacheck, V., Schöfer, C., Pehamberger, H., Müller, M., & Lucas, T. (2004). Loss of novel mda-7 splice variant (mda-7s) expression is associated with metastatic melanoma. The Journal of Investigative Dermatology, 123(3), 583–588

Article  Google Scholar 

Sahoo, A., Jung, Y. M., Kwon, H. K., Yi, H. J., Lee, S., Chang, S., Park, Z. Y., Hwang, K. C., & Im, S. H. (2008). A novel splicing variant of mouse interleukin (IL)-24 antagonizes IL-24-induced apoptosis. The Journal of Biological Chemistry, 283(43), 28860–28872

Article  Google Scholar 

Filippov, V., Schmidt, E. L., Filippova, M., & Duerksen-Hughes, P. J. (2008). Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes. Gene, 420(1), 34–41

Article  Google Scholar 

Whitaker, E. L., Filippov, V., Filippova, M., Guerrero-Juarez, C. F., & Duerksen-Hughes, P. J. (2011). Splice variants of mda-7/IL-24 differentially affect survival and induce apoptosis in U2OS cells. Cytokine, 56(2), 272–281

Article  Google Scholar 

Valiyari, S., Salami, M., Mahdian, R., Shokrgozar, M. A., Oloomi, M., Mohammadi Farsani, A., & Bouzari, S. (2017). sIL-24 peptide, a human interleukin-24 isoform, induces mitochondrial-mediated apoptosis in human cancer cells. Cancer Chemotherapy and Pharmacology, 80(3), 451–459

Article  Google Scholar 

Dudakov, J. A., Hanash, A. M., & van den Brink, M. R. (2015). Interleukin-22: Immunobiology and pathology. Annual Review of Immunology, 33, 747–785

Article  Google Scholar 

Sabat, R., Wallace, E., Endesfelder, S., & Wolk, K. (2007). IL-19 and IL-20: Two novel cytokines with importance in inflammatory diseases. Expert Opinion on Therapeutic Targets, 11(5), 601–612.

Article  Google Scholar 

Kunz, S., Wolk, K., Witte, E., Witte, K., Doecke, W. D., Volk, H. D., Sterry, W., Asadullah, K., & Sabat, R. (2006). Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are distinct from classical ILs. Experimental dermatology, 15(12), 991–1004.

Article  Google Scholar 

Su, T. P., Su, T. C., Nakamura, Y., & Tsai, S. Y. (2016). The sigma-1 receptor as a pluripotent modulator in living systems. Trends in Pharmacological Sciences, 37(4), 262–278

Article  Google Scholar 

Maarof, G., Bouchet-Delbos, L., Gary-Gouy, H., Durand-Gasselin, I., Krzysiek, R., & Dalloul, A. (2010). Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells. Blood, 115(9), 1718–1726

Article  Google Scholar 

Hadife, N., Nemos, C., Frippiat, J. P., Hamadé, T., Perrot, A., & Dalloul, A. (2013). Interleukin-24 mediates apoptosis in human B-cells through early activation of cell cycle arrest followed by late induction of the mitochondrial apoptosis pathway. Leukemia & Lymphoma, 54(3), 587–597

Article  Google Scholar 

Dabitao, D., Hedrich, C. M., Wang, F., Vacharathit, V., & Bream, J. H. (2018). Cell-specific requirements for STAT proteins and type I IFN receptor signaling discretely regulate IL-24 and IL-10 expression in NK cells and macrophages. The Journal of Immunology, 200(6), 2154–2164

Article  Google Scholar 

Poindexter, N. J., Walch, E. T., Chada, S., & Grimm, E. A. (2005). Cytokine induction of interleukin-24 in human peripheral blood mononuclear cells. Journal of Leukocyte Biology, 78(3), 745–752

Article  Google Scholar 

Tang, Y., Sun, X., Wang, Y., Luan, H., Zhang, R., Hu, F., Sun, X., Li, X., & Guo, J. (2021). Role of IL-24 in NK cell activation and its clinical implication in systemic lupus erythematosus. Clinical Rheumatology, 40(7), 2707–2715

Article  Google Scholar 

Yang, H. L., Zhou, W. J., Lu, H., Lei, S. T., Ha, S. Y., Lai, Z. Z., Zheng, Z. M., Ruan, L. Y., He, Y. Y., Li, D. J., Li, M. Q., & Shao, J. (2019). Decidual stromal cells promote the differentiation of CD56bright CD16- NK cells by secreting IL-24 in early pregnancy. American Journal of Reproductive Immunology, 81(6), 13110

Article  Google Scholar 

Yang, H. L., Wang, C. J., Lai, Z. Z., Yang, S. L., Zheng, Z. M., Shi, J. W., Li, M. Q., & Shao, J. (2020). Decidual stromal cells maintain decidual macrophage homeostasis by secreting IL-24 in early pregnancy. American Journal of Reproductive Immunology, 84(2), 13261

Article  Google Scholar 

Garn, H., Schmidt, A., Grau, V., Stumpf, S., Kaufmann, A., Becker, M., Gemsa, D., & Siese, A. (2002). IL-24 is expressed by rat and human macrophages. Immunobiology, 205(3), 321–334

Article  Google Scholar 

Rao, L. Z., Wang, Y., Zhang, L., Wu, G., Zhang, L., Wang, F. X., Chen, L. M., Sun, F., Jia, S., Zhang, S., Yu, Q., Wei, J. H., Lei, H. R., Yuan, T., Li, J., Huang, X., Cheng, B., Zhao, J., Xu, Y., Mo, B. W., Wang, C. Y., & Zhang, H. (2021). IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages. Cell Death and Differentiation, 28(4), 1270–1283

Article  Google Scholar 

Buzas, K., Oppenheim, J. J., & Zack Howard, O. M. (2011). Myeloid cells migrate in response to IL-24. Cytokine, 55(3), 429–434

Article  Google Scholar 

Schaefer, G., Venkataraman, C., & Schindler, U. (2001). Cutting edge: FISP (IL-4-induced secreted protein), a novel cytokine-like molecule secreted by Th2 cells. The Journal of Immunology, 166(10), 5859–5863

Article  Google Scholar 

Wei, L., Vahedi, G., Sun, H. W., Watford, W. T., Takatori, H., Ramos, H. L., Takahashi, H., Liang, J., Gutierrez-Cruz, G., Zang, C., Peng, W., O'Shea, J. J., & Kanno, Y. (2010). Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity, 32(6), 840–851

Article  Google Scholar 

Sahoo, A., Lee, C. G., Jash, A., Son, J. S., Kim, G., Kwon, H. K., So, J. S., & Im, S. H. (2011). Stat6 and c-Jun mediate Th2 cell-specific IL-24 gene expression. The Journal of Immunology, 186(7), 4098–4109

Article  Google Scholar 

Oral, H. B., Kotenko, S. V., Yilmaz, M., Mani, O., Zumkehr, J., Blaser, K., Akdis, C. A., & Akdis, M. (2006). Regulation of T cells and cytokines by the interleukin-10 (IL-10)-family cytokines IL-19, IL-20, IL-22, IL-24 and IL-26. European Journal of Immunology, 36(2), 380–388

Article  Google Scholar 

Anuradha, R., George, P. J., Hanna, L. E., Kumaran, P., Chandrasekaran, V., Nutman, T. B., & Babu, S. (2014). Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis. PLoS Neglected Tropical Diseases, 8(4), e2762

Article  Google Scholar 

Kumar, N. P., Moideen, K., Banurekha, V. V., Nair, D., & Babu, S. (2018). Modulation of Th1/Tc1 and Th17/Tc17 responses in pulmonary tuberculosis by IL-20 subfamily of cytokines. Cytokine, 108, 190–196

Article  Google Scholar 

Chong, W. P., Mattapallil, M. J., Raychaudhuri, K., Bing, S. J., Wu, S., Zhong, Y., Wang, W., Chen, Z., Silver, P. B., Jittayasothorn, Y., Chan, C. C., Chen, J., Horai, R., & Caspi, R. R. (2020). The cytokine IL-17A limits Th17 pathogenicity via a negative feedback loop driven by autocrine induction of IL-24. Immunity, 53(2), 384–397.e5

Article  Google Scholar 

Zhang, Y., Liu, Y., & Xu, Y. (2019). Interleukin-24 regulates T cell activity in patients with colorectal adenocarcinoma. Frontiers in Oncology, 9, 1401

Article