Fabris L, Sato K, Alpini G, Strazzabosco M. The tumor microenvironment in cholangiocarcinoma progression. Hepatology. 2021;73(1):75–85
Palmieri LJ, Lavolé J, Dermine S, et al. The choice for the optimal therapy in advanced biliary tract cancers: chemotherapy, targeted therapies or immunotherapy. Pharmacol Ther. 2020;210: 107517
O’Rourke CJ, Munoz-Garrido P, Andersen JB. Molecular targets in cholangiocarcinoma. Hepatology. 2021;73(Suppl 1):62–74
Gump JM, Thorburn A. Autophagy and apoptosis: what is the connection. Trends Cell Biol. 2011;21(7):387–392
PubMed PubMed Central Google Scholar
Mariño G, Niso-Santano M, Baehrecke EH, Kroemer G. Self-consumption: the interplay of autophagy and apoptosis. Nat Rev Mol Cell Biol. 2014;15(2):81–94
PubMed PubMed Central Google Scholar
Burke PJ. Mitochondria, bioenergetics and apoptosis in cancer. Trends Cancer. 2017;3(12):857–870
PubMed PubMed Central Google Scholar
Wang L, Zhu Y, Zhang L, et al. Mechanisms of PANoptosis and relevant small-molecule compounds for fighting diseases. Cell Death Dis. 2023;14(12):851
PubMed PubMed Central Google Scholar
Lu JL, Yu CX, Song LJ. Programmed cell death in hepatic fibrosis: current and perspectives. Cell Death Discov. 2023;9(1):449
PubMed PubMed Central Google Scholar
Zhang HR, Li YP, Shi ZJ, et al. Triptolide induces PANoptosis in macrophages and causes organ injury in mice. Apoptosis. 2023;28(11–12):1646–1665
Pandeya A, Kanneganti TD. Therapeutic potential of PANoptosis: innate sensors, inflammasomes, and RIPKs in PANoptosomes. Trends Mol Med. 2023;S1471–4914(23):00236–00238
Zhou L, Lyu J, Liu F, Su Y, Feng L, Zhang X. Immunogenic PANoptosis-initiated cancer sono-immune reediting nanotherapy by iteratively boosting cancer immunity cycle. Adv Mater. 2023;36(2):e2305361
Shi X, Gao X, Liu W, et al. Construction of the panoptosis-related gene model and characterization of tumor microenvironment infiltration in hepatocellular carcinoma. Oncol Res. 2023;31(4):569–590
PubMed PubMed Central Google Scholar
Wei Y, Lan C, Yang C, et al. Robust analysis of a novel PANoptosis-related prognostic gene signature model for hepatocellular carcinoma immune infiltration and therapeutic response. Sci Rep. 2023;13(1):14519
PubMed PubMed Central Google Scholar
Song F, Wang CG, Mao JZ, et al. PANoptosis-based molecular subtyping and HPAN-index predicts therapeutic response and survival in hepatocellular carcinoma. Front Immunol. 2023;14:1197152
PubMed PubMed Central Google Scholar
Zhang B, Huang B, Zhang X, et al. PANoptosis-related molecular subtype and prognostic model associated with the immune microenvironment and individualized therapy in pancreatic cancer. Front Oncol. 2023;13:1217654
PubMed PubMed Central Google Scholar
Wei S, Chen Z, Ling X, Zhang W, Jiang L. Comprehensive analysis illustrating the role of PANoptosis-related genes in lung cancer based on bioinformatic algorithms and experiments. Front Pharmacol. 2023;14:1115221
PubMed PubMed Central Google Scholar
Hu Q, Wang R, Zhang J, Xue Q, Ding B. Tumor-associated neutrophils upregulate PANoptosis to foster an immunosuppressive microenvironment of non-small cell lung cancer. Cancer Immunol Immunother. 2023;72(12):4293–4308
PubMed PubMed Central Google Scholar
Zhang C, Xia J, Liu X, et al. Identifying prognostic genes related PANoptosis in lung adenocarcinoma and developing prediction model based on bioinformatics analysis. Sci Rep. 2023;13(1):17956
PubMed PubMed Central Google Scholar
Wang Y, Zhou J, Zhang N, et al. A novel defined PANoptosis-related miRNA signature for predicting the prognosis and immune characteristics in clear cell renal cell carcinoma: a miRNA signature for the prognosis of ccRCC. Int J Mol Sci. 2023;24(11):9392
PubMed PubMed Central Google Scholar
Liu W, Qu C, Wang X. Comprehensive analysis of the role of immune-related PANoptosis lncRNA model in renal clear cell carcinoma based on RNA transcriptome and single-cell sequencing. Oncol Res. 2023;31(4):543–567
PubMed PubMed Central Google Scholar
Malireddi R, Tweedell RE, Kanneganti TD. PANoptosis components, regulation, and implications. Aging (Albany NY). 2020;12(12):11163–11164
Malireddi R, Kesavardhana S, Kanneganti TD. ZBP1 and TAK1: Master Regulators of NLRP3 inflammasome/pyroptosis, apoptosis, and necroptosis (PAN-optosis). Front Cell Infect Microbiol. 2019;9:406
PubMed PubMed Central Google Scholar
Karki R, Sharma BR, Lee E, et al. Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer. JCI Insight. 2020;5(12): e136720
PubMed PubMed Central Google Scholar
Samir P, Malireddi R, Kanneganti TD. The PANoptosome: a deadly protein complex driving pyroptosis, apoptosis, and necroptosis (PANoptosis). Front Cell Infect Microbiol. 2020;10:238
PubMed PubMed Central Google Scholar
Briard B, Malireddi R, Kanneganti TD. Role of inflammasomes/pyroptosis and PANoptosis during fungal infection. PLoS Pathog. 2021;17(3): e1009358
PubMed PubMed Central Google Scholar
Jiang M, Qi L, Li L, Wu Y, Song D, Li Y. Caspase-8: A key protein of cross-talk signal way in “PANoptosis” in cancer. Int J Cancer. 2021;149(7):1408–1420
Lee S, Karki R, Wang Y, Nguyen LN, Kalathur RC, Kanneganti TD. AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence. Nature. 2021;597(7876):415–419
PubMed PubMed Central Google Scholar
Place DE, Lee S, Kanneganti TD. PANoptosis in microbial infection. Curr Opin Microbiol. 2021;59:42–49
Nguyen LN, Kanneganti TD. PANoptosis in viral infection: the missing puzzle piece in the cell death field. J Mol Biol. 2022;434(4): 167249
Kinoshita M, Kobayashi S, Gotoh K, et al. Heterogeneity of treg/Th17 according to cancer progression and modification in biliary tract cancers via self-producing cytokines. Dig Dis Sci. 2020;65(10):2937–2948
Shiode Y, Kodama T, Shigeno S, et al. TNF receptor-related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF-κB-inducing kinase-mediated hepatocyte transdifferentiation. Hepatology. 2023;77(2):395–410
Liu ZH, Lian BF, Dong QZ, et al. 2018 Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity. Biochim Biophys Acta Mol Basis Dis. 1864;6:2360–2368
Pan YR, Lai JC, Huang WK, et al. PLK1 and its substrate MISP facilitate intrahepatic cholangiocarcinoma progression by promoting lymphatic invasion and impairing E-cadherin adherens junctions. Cancer Gene Ther. 2024;31(2):322–333
Lavacchi D, Caliman E, Rossi G, et al. Ivosidenib in IDH1-mutated cholangiocarcinoma: clinical evaluation and future directions. Pharmacol Ther. 2022;237: 108170
Sapisochin G, Ivanics T, Heimbach J. Liver Transplantation for intrahepatic cholangiocarcinoma: ready for prime time. Hepatology. 2022;75(2):455–472
Yi X, Li J, Zheng X, et al. Construction of PANoptosis signature: novel target discovery for prostate cancer immunotherapy. Mol Ther Nucleic Acids. 2023;33:376–390
PubMed PubMed Central Google Scholar
Oh S, Lee J, Oh J, et al. Integrated NLRP3, AIM2, NLRC4, pyrin inflammasome activation and assembly drive PANoptosis. Cell Mol Immunol. 2023;20(12):1513–1526
Wang Y, Pandian N, Han JH, et al. Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method. Cell Mol Life Sci. 2022;79(10):531
Nicolè L, Sanavia T, Cappellesso R, et al. Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3(+) and CD8(+) T cell density and predict prognosis in hepatocellular carcinoma. J Immunother Cancer. 2022;10(3): e004031
PubMed PubMed Central Google Scholar
Lomphithak T, Akara-Amornthum P, Murakami K, et al. Tumor necroptosis is correlated with a favorable immune cell signature and programmed death-ligand 1 expression in cholangiocarcinoma. Sci Rep. 2021;11(1):11743
PubMed PubMed Central Google Scholar
Song X, Xu H, Wang P, et al. Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation. J Hepatol. 2021;75(4):888–899
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