A dual role of ERGIC-localized Rabs in TMED10-mediated unconventional protein secretion

Shan, S. O. & Walter, P. Co-translational protein targeting by the signal recognition particle. FEBS Lett. 579, 921–926 (2005).

Article  CAS  PubMed  Google Scholar 

Voorhees, R. M. & Hegde, R. S. Toward a structural understanding of co-translational protein translocation. Curr. Opin. Cell Biol. 41, 91–99 (2016).

Article  CAS  PubMed  Google Scholar 

Rapoport, T. A., Li, L. & Park, E. Structural and mechanistic insights into protein translocation. Annu. Rev. Cell Dev. Biol. 33, 369–390 (2017).

Article  CAS  PubMed  Google Scholar 

Zanetti, G., Pahuja, K. B., Studer, S., Shim, S. & Schekman, R. COPII and the regulation of protein sorting in mammals. Nat. Cell Biol. 14, 20–28 (2011).

Article  PubMed  Google Scholar 

Pantazopoulou, A. & Glick, B. S. A kinetic view of membrane traffic pathways can transcend the classical view of Golgi compartments. Front. Cell Dev. Biol. 7, 153 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Nickel, W. & Rabouille, C. Mechanisms of regulated unconventional protein secretion. Nat. Rev. Mol. Cell Biol. 10, 148–155 (2009).

Article  CAS  PubMed  Google Scholar 

Rabouille, C., Malhotra, V. & Nickel, W. Diversity in unconventional protein secretion. J. Cell Sci. 125, 5251–5255 (2012).

Article  CAS  PubMed  Google Scholar 

Malhotra, V. Unconventional protein secretion: an evolving mechanism. EMBO J. 32, 1660–1664 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang, M. & Schekman, R. Cell biology. Unconventional secretion, unconventional solutions. Science 340, 559–561 (2013).

Article  CAS  PubMed  Google Scholar 

Rabouille, C. Pathways of unconventional protein secretion. Trends Cell Biol. 27, 230–240 (2017).

Article  CAS  PubMed  Google Scholar 

Dimou, E. & Nickel, W. Unconventional mechanisms of eukaryotic protein secretion. Curr. Biol. 28, R406–R410 (2018).

Article  CAS  PubMed  Google Scholar 

Steringer, J. P. & Nickel, W. A direct gateway into the extracellular space: unconventional secretion of FGF2 through self-sustained plasma membrane pores. Semin. Cell Dev. Biol. 83, 3–7 (2018).

Article  CAS  PubMed  Google Scholar 

Schafer, T. et al. Unconventional secretion of fibroblast growth factor 2 is mediated by direct translocation across the plasma membrane of mammalian cells. J. Biol. Chem. 279, 6244–6251 (2004).

Article  PubMed  Google Scholar 

Duran, J. M., Anjard, C., Stefan, C., Loomis, W. F. & Malhotra, V. Unconventional secretion of Acb1 is mediated by autophagosomes. J. Cell Biol. 188, 527–536 (2010).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cruz-Garcia, D., Brouwers, N., Malhotra, V. & Curwin, A. J. Reactive oxygen species triggers unconventional secretion of antioxidants and Acb1. J. Cell Biol. 219, e201905028 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lock, R., Kenific, C. M., Leidal, A. M., Salas, E. & Debnath, J. Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion. Cancer Discov. 4, 466–479 (2014).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Villeneuve, J. et al. Unconventional secretion of FABP4 by endosomes and secretory lysosomes. J. Cell Biol. 217, 649–665 (2018).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ejlerskov, P. et al. Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion. J. Biol. Chem. 288, 17313–17335 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Claude-Taupin, A., Jia, J., Mudd, M. & Deretic, V. Autophagy’s secret life: secretion instead of degradation. Essays Biochem. 61, 637–647 (2017).

Article  PubMed  Google Scholar 

Zhang, M. et al. A translocation pathway for vesicle-mediated unconventional protein secretion. Cell 181, 637–652 (2020).

Article  CAS  PubMed  Google Scholar 

Zhang, M., Kenny, S. J., Ge, L., Xu, K. & Schekman, R. Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion. eLife 4, e11205 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Dupont, N. et al. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β. EMBO J. 30, 4701–4711 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rubartelli, A., Cozzolino, F., Talio, M. & Sitia, R. A novel secretory pathway for interleukin-1-β, a protein lacking a signal sequence. EMBO J. 9, 1503–1510 (1990).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rubartelli, A., Bajetto, A., Allavena, G., Cozzolino, F. & Sitia, R. Posttranslational regulation of interleukin-1-β secretion. Cytokine 5, 117–124 (1993).

Article  CAS  PubMed  Google Scholar 

Dirac-Svejstrup, A. B., Sumizawa, T. & Pfeffer, S. R. Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI. EMBO J. 16, 465–472 (1997).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Goody, R. S., Müller, M. P. & Wu, Y. W. Mechanisms of action of Rab proteins, key regulators of intracellular vesicular transport. Biol. Chem. 398, 565–575 (2017).

Article  CAS  PubMed  Google Scholar 

Pfeffer, S. R. Rab GTPases: master regulators that establish the secretory and endocytic pathways. Molec. Biol. Cell 28, 712–715 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang, X. H. et al. SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion. J. Cell Biol. 221, e202111125 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, X. X. et al. Coordination of RAB-8 and RAB-11 during unconventional protein secretion. J. Cell Biol. 223, e202306107 (2023).

Pfeffer, S. R. Rab GTPase regulation of membrane identity. Curr. Opin. Cell Biol. 25, 414–419 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stenmark, H. Rab GTPases as coordinators of vesicle traffic. Nat. Rev. Mol. Cell Biol. 10, 513–525 (2009).

Article  CAS  PubMed  Google Scholar 

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