American Psychiatric Association. Diagnostic and statistical Manual of Mental disorders. Fifth ed. Washington, DC: American Psychiatric Association; 2013.
Peterson RL, Pennington BF. Developmental dyslexia. Annu Rev Clin Psychol. 2015;11:283–307.
Sexton T, Yaffe E, Kenigsberg E, Bantignies F, Leblanc B, Hoichman M, et al. Three-Dimensional folding and Functional Organization principles of the Drosophila genome. Cell. 2012;148(3):458–72.
Article CAS PubMed Google Scholar
Hallgren B. Specific dyslexia (congenital word-blindness); a clinical and genetic study. Acta Psychiatr Neurol Suppl. 1950;65:1–287.
Fisher SE, DeFries JC. Developmental dyslexia: genetic dissection of a complex cognitive trait. Nat Rev Neurosci. 2002;3(10):767–80.
Article CAS PubMed Google Scholar
Plomin R, Kovas Y. Generalist Genes Learn Disabil Psychol Bull;131(4):592–617.
Mascheretti S, De Luca A, Trezzi V, et al. Neurogenetics of developmental dyslexia: from genes to behavior through brain neuroimaging and cognitive and sensorial mechanisms. Transl Psychiatry. 2017;7:e987.
Article CAS PubMed PubMed Central Google Scholar
Scerri TS, Schulte-Körne G. Genetics of developmental dyslexia. Eur Child Adolesc Psychiatry. 2009;19(3):179–97.
Gialluisi A, Newbury DF, Wilcutt EG, Olson RK, DeFries JC, Brandler WM, Fisher SE. Genome-wide screening for DNA variants associated with reading and language traits. Genes Brain Behav. 2014;13(7):686–701.
Article CAS PubMed Google Scholar
Gialluisi A, Andlauer TFM, Mirza-Schreiber N, et al. Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. Transl Psychiatry. 2019;9(1):77.
Article PubMed PubMed Central Google Scholar
Gialluisi A, Andlauer TFM, Mirza-Schreiber N, Moll K, Becker J, Hoffmann P, et al. Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia. Mol Psychiatry. 2021;26:3004–17.
Article CAS PubMed Google Scholar
Truong DT, Adams AK, Paniagua S, Frijters JC, Boada R, Hill DE, et al. Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth. J Med Genet. 2019;56(8):557–66.
Article CAS PubMed Google Scholar
Price KM, Wigg KG, Eising E, Feng Y, Blokland K, Wilkinson M et al. Hypothesis-driven genome-wide association studies provide novel insights into genetics of reading disabilities. Translational Psychiatry 2022;12(495).
Price KM, Wigg KG, Feng Y, Blokland K, Wilkinson M, He G et al. Genome-wide association study of word reading: overlap with risk genes for neurodevelopmental disorders. Genes Brain Behav 2020;19(6).
Doust C, Fontanillas P, Eising E, Gordon SD, Wang Z, Alagöz G, et al. Discovery of 42 genome-wide significant loci associated with dyslexia. Nat Genet. 2022;54(11):1621–9.
Article CAS PubMed PubMed Central Google Scholar
Eising E et al. Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people. Proceedings of the National Academy of Sciences. 2022;119(35).
Wang Z, Zhao S, Zhang L, Yang Q, Cheng C, Ding N, et al. A genome-wide association study identifies a new variant associated with word reading fluency in Chinese children. Genes Brain Behav. 2023;22(1):e12833.
Article CAS PubMed Google Scholar
Becker J, Czamara D, Scerri T, et al. Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort. Eur J Hum Genet. 2014;22:675–80.
Article CAS PubMed Google Scholar
Lampis V, Ventura R, Di Segni M, Marino C, D’Amato FR, Mascheretti S. Animal models of developmental dyslexia: where we are and what we are missing. Neurosci Biobehav Rev. 2021;131:1180–97.
Article CAS PubMed Google Scholar
Meng H, Smith SD, Hager K, Held M, Liu J, Olson RK et al. DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proceedings of the National Academy of Sciences. 2005;102(47):17053–17058.
Che A, Girgenti MJ, LoTurco J. The dyslexia-associated gene DCDC2 is required for spike-timing precision in mouse neocortex. Biol Psychiatry. 2014;76(5):387–96.
Article CAS PubMed Google Scholar
Brkanac Z, Chapman NH, Matsushita MM, Chun L, Nielsen K, Cochrane E, et al. Evaluation of candidate genes for DYX1 and DYX2 in families with dyslexia. Am J Med Genet Part B: Neuropsychiatric Genet. 2007;144(4):556–60.
Chen Y, Zhao H, Zhang YX, Zuo P. X. DCDC2 gene polymorphisms are associated with developmental dyslexia in Chinese uyghur children. Neural Regeneration Res. 2017;12(2):259–66.
Cope N, Harold D, Hill G, Moskvina V, Stevenson J, Holmans P, et al. Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. Am J Hum Genet. 2005;76(4):581–91.
Article CAS PubMed PubMed Central Google Scholar
Harold D, Paracchini S, Scerri T, Dennis M, Cope N, Hill G, Moskvina V, Walter J, Richardson AJ, Owen MJ, Stein JF, et al. Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia. Mol Psychiatry. 2006;11:1085–91.
Article CAS PubMed Google Scholar
Ludwig KU, Schumacher J, Schulte-Körne G, König IR, Warnke A, Plume E, et al. Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample. Psychiatr Genet. 2008;18(6):310–2.
Article PubMed PubMed Central Google Scholar
Marino C, Meng H, Mascheretti S, Rusconi M, Cope N, Giorda R, Molteni M, Gruen JR. DCDC2 genetic variants and susceptibility to developmental dyslexia. Psychiatr Genet. 2012;22(1):25–30.
Article CAS PubMed PubMed Central Google Scholar
Matsson H, Huss M, Persson H, Einarsdottir E, Tiraboschi E, Nopola-Hemmi J, et al. Polymorphisms in DCDC2 and S100B associate with developmental dyslexia. J Hum Genet. 2015;60(7):399–401.
Article CAS PubMed PubMed Central Google Scholar
Riva V, Mozzi A, Forni D, Trezzi V, Giorda R, Riva S, et al. The influence of DCDC2 risk genetic variants on reading: testing main and haplotypic effects. Neuropsychologia. 2019;130:52–8.
Schumacher J, Anthoni H, Dahdouh F, König IR, Hillmer AM, Kluck N, et al. Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia. Am J Hum Genet. 2006;78(1):52–62.
Article CAS PubMed Google Scholar
Sun Y, Gao Y, Zhou Y, Chen H, Wang G, Xu J, et al. Association study of developmental dyslexia candidate genes DCDC2 and KIAA0319 in Chinese population. Am J Med Genet Part B: Neuropsychiatric Genet. 2014;165(8):627–34.
Venkatesh SK, Siddaiah A, Padakannaya P, Ramachandra NB. Analysis of genetic variants of dyslexia candidate genes KIAA0319 and DCDC2 in Indian population. J Hum Genet. 2013;58(8):531–8.
Article CAS PubMed Google Scholar
Wilcke A, Weissfuss &J, Kirsten H, Wolfram G, Boltze J, Ahnert P. The role of gene DCDC2 in German dyslexics. Annals of dyslexia. 2008;59:1–11.
Zhong R, Yang B, Tang H, Zou L, Song R, Zhu L-Q, et al. Meta-analysis of the association between DCDC2 polymorphisms and risk of dyslexia. Mol Neurobiol. 2013;47(1):435–42.
Article CAS PubMed Google Scholar
Lind PA, Luciano M, Wright MJ, Montgomery GW, Martin NG, Bates TC. Dyslexia and DCDC2: normal variation in reading and spelling is associated with DCDC2 polymorphisms in an Australian population sample. Eur J Hum Genet. 2010;18(6):668–73.
Article CAS PubMed PubMed Central Google Scholar
Newbury, D. F., Paracchini, S., Scerri, T. S., Winchester, L., Addis, L., Richardson, A. J., ... & Monaco, A. P. Investigation of dyslexia and SLI risk variants in reading-and language-impaired subjects. Behavior genetics 2011;41(1):90–104.
Powers NR, Eicher JD, Butter F, Kong Y, Miller LL, Ring SM, et al. Alleles of a polymorphic ETV6 binding site in DCDC2 Confer Risk of Reading and Language Impairment. Am J Hum Genet. 2013;93(1):19–28.
留言 (0)