Abskharon R, Wang F, Wohlkonig A, Ruan J, Soror S, Giachin G, Pardon E, Zou W, Legname G, Ma J, Steyaert J (2019) Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion. PLoS Pathog 15(12):e1008139

Article  PubMed  PubMed Central  Google Scholar 

Advani VM, Ivanov P (2019) Translational Control under Stress: Reshaping the Translatome. BioEssays 41(5):e1900009

Article  PubMed  PubMed Central  Google Scholar 

Alais S, Soto-Rifo R, Balter V, Gruffat H, Manet E, Schaeffer L, Darlix JL, Cimarelli A, Raposo G, Ohlmann T, Leblanc P (2012) Functional mechanisms of the cellular prion protein (PrP(C)) associated anti-HIV-1 properties. Cell Mol Life Sci 69(8):1331–1352

Article  CAS  PubMed  Google Scholar 

Altmeppen HC, Prox J, Krasemann S, Puig B, Kruszewski K, Dohler F, Bernreuther C, Hoxha A, Linsenmeier L, Sikorska B, Liberski PP, Bartsch U, Saftig P, Glatzel M (2015) The sheddase ADAM10 is a potent modulator of prion disease. Elife 4:e04260

Article  PubMed  PubMed Central  Google Scholar 

Bakkebø MK, Mouillet-Richard S, Espenes A, Goldmann W, Tatzelt J, Tranulis MA (2015) The Cellular Prion Protein: A Player in Immunological Quiescence. Front Immunol 6:450

Article  PubMed  PubMed Central  Google Scholar 

Bertuchi FR, Bourgeon DM, Landemberger MC, Martins VR, Cerchiaro G (2012) PrPC displays an essential protective role from oxidative stress in an astrocyte cell line derived from PrPC knockout mice. Biochem Biophys Res Commun 418(1):27–32

Article  CAS  PubMed  Google Scholar 

Borchelt DR, Koliatsos VE, Guarnieri M, Pardo CA, Sisodia SS, Price DL (1994) Rapid anterograde axonal transport of the cellular prion glycoprotein in the peripheral and central nervous systems. J Biol Chem 269(20):14711–14714

Article  CAS  PubMed  Google Scholar 

Bose A, Basu R, Maulik M, Das Sarma J (2018) Loss of Cx43-Mediated Functional Gap Junction Communication in Meningeal Fibroblasts Following Mouse Hepatitis Virus Infection. Mol Neurobiol 55(8):6558–6571

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bose A, Kasle G, Jana R, Maulik M, Thomas D, Mulchandani V, Mukherjee P, Koval M, Das Sarma J (2023) Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine β-coronavirus host cell response. J Biol Chem 299(2):102836

Article  CAS  PubMed  Google Scholar 

Brown DR, Besinger A, Herms JW, Kretzschmar HA (1998) Microglial expression of the prion protein. NeuroReport 9(7):1425–1429

Article  CAS  PubMed  Google Scholar 

Carulla P, Bribián A, Rangel A, Gavín R, Ferrer I, Caelles C, Del Río JA, Llorens F (2011) Neuroprotective role of PrPC against kainate-induced epileptic seizures and cell death depends on the modulation of JNK3 activation by GluR6/7-PSD-95 binding. Mol Biol Cell 22(17):3041–3054

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carulla P, Llorens F, Matamoros-Angles A, Aguilar-Calvo P, Espinosa JC, Gavín R, Ferrer I, Legname G, Torres JM, del Río JA (2015) Involvement of PrP(C) in kainate-induced excitotoxicity in several mouse strains. Sci Rep 5:11971

Article  PubMed  PubMed Central  Google Scholar 

Caruso P, Burla R, Piersanti S, Cherubini G, Remoli C, Martina Y, Saggio I (2009) Prion expression is activated by Adenovirus 5 infection and affects the adenoviral cycle in human cells. Virology 385(2):343–350

Article  CAS  PubMed  Google Scholar 

Castle AR, Gill AC (2017) Physiological Functions of the Cellular Prion Protein. Front Mol Biosci 4:19

Article  PubMed  PubMed Central  Google Scholar 

Collins S, McLean CA, Masters CL (2001) Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies. J Clin Neurosci 8(5):387–397

Article  CAS  PubMed  Google Scholar 

Das Sarma J (2010) A mechanism of virus-induced demyelination. Interdiscip Perspect Infect Dis 2010:109239

Article  PubMed  PubMed Central  Google Scholar 

Das Sarma J, Iacono K, Gard L, Marek R, Kenyon LC, Koval M, Weiss SR (2008) Demyelinating and nondemyelinating strains of mouse hepatitis virus differ in their neural cell tropism. J Virol 82(11):5519–5526

Article  CAS  PubMed  PubMed Central  Google Scholar 

Das Sarma J, Kenyon LC, Hingley ST, Shindler KS (2009) Mechanisms of primary axonal damage in a viral model of multiple sclerosis. J Neurosci 29(33):10272–10280

Article  CAS  PubMed  PubMed Central  Google Scholar 

Das Sarma J, Scheen E, Seo SH, Koval M, Weiss SR (2002) Enhanced green fluorescent protein expression may be used to monitor murine coronavirus spread in vitro and in the mouse central nervous system. J Neurovirol 8(5):381–391

Article  CAS  PubMed  PubMed Central  Google Scholar 

DeDiego ML, Nieto-Torres JL, Regla-Nava JA, Jimenez-Guardeño JM, Fernandez-Delgado R, Fett C, Castaño-Rodriguez C, Perlman S, Enjuanes L (2014) Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival. J Virol 88(2):913–924

Article  PubMed  PubMed Central  Google Scholar 

Dibner C, Schibler U, Albrecht U (2010) The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu Rev Physiol 72:517–549

Article  CAS  PubMed  Google Scholar 

Faris R, Moore RA, Ward A, Race B, Dorward DW, Hollister JR, Fischer ER, Priola SA (2017) Cellular prion protein is present in mitochondria of healthy mice. Sci Rep 7:41556

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haeberlé AM, Ribaut-Barassin C, Bombarde G, Mariani J, Hunsmann G, Grassi J, Bailly Y (2000) Synaptic prion protein immuno-reactivity in the rodent cerebellum. Microsc Res Tech 50(1):66–75

Article  PubMed  Google Scholar 

Haraguchi T, Fisher S, Olofsson S, Endo T, Groth D, Tarentino A, Borchelt DR, Teplow D, Hood L, Burlingame A et al (1989) Asparagine-linked glycosylation of the scrapie and cellular prion proteins. Arch Biochem Biophys 274(1):1–13

Article  CAS  PubMed  Google Scholar 

Harris DA, Huber MT, van Dijken P, Shyng SL, Chait BT, Wang R (1993) Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites. Biochemistry 32(4):1009–1016

Article  CAS  PubMed  Google Scholar 

Herms J, Tings T, Gall S, Madlung A, Giese A, Siebert H, Schürmann P, Windl O, Brose N, Kretzschmar H (1999) Evidence of presynaptic location and function of the prion protein. J Neurosci 19(20):8866–8875

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hong JM, Munna AN, Moon JH, Kim JH, Seol JW, Eo SK, Park SY (2023) Antiviral activity of prion protein against Japanese encephalitis virus infection in vitro and in vivo. Virus Res 338:199249

Article  CAS  PubMed  PubMed Central  Google Scholar 

Küffer A, Lakkaraju AK, Mogha A, Petersen SC, Airich K, Doucerain C, Marpakwar R, Bakirci P, Senatore A, Monnard A, Schiavi C, Nuvolone M, Grosshans B, Hornemann S, Bassilana F, Monk KR, Aguzzi A (2016) The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6. Nature 536(7617):464–468

Article  PubMed  PubMed Central  Google Scholar 

Lavi E, Gilden D