Shen MJ, Arora R, Jalife J (2019) Atrial myopathy. JACC Basic Transl Sci 4(5):640–654. https://doi.org/10.1016/j.jacbts.2019.05.005

Article  PubMed  PubMed Central  Google Scholar 

Li CY, Zhang JR, Hu WN et al (2021) Atrial fibrosis underlying atrial fibrillation (review). Int J Mol Med 47(3):9. https://doi.org/10.3892/ijmm.2020.4842

Article  CAS  PubMed  Google Scholar 

Rohr S (2012) Arrhythmogenic implications of fibroblast-myocyte interactions. Circ Arrhythm Electrophysiol 5(2):442–452. https://doi.org/10.1161/CIRCEP.110.957647

Article  PubMed  Google Scholar 

Mahnkopf C, Mitlacher M, Brachmann J et al (2015) The degree of left atrial fibrosis as a potential risk factor for stroke: lessons learned from cardiac MRI. J Am Coll Cardiol 65(10):1180. https://doi.org/10.1016/S0735-1097(15)61180-9

Article  Google Scholar 

Pontecorboli G, Figueras I, Ventura RM et al (2017) Use of delayed-enhancement magnetic resonance imaging for fibrosis detection in the atria: a review. Europace 19(2):180–189. https://doi.org/10.1093/europace/euw053

Article  PubMed  Google Scholar 

Marrouche NF, Wilber D, Hindricks G et al (2014) Association of atrial tissue fibrosis identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF study. JAMA 311(5):498–506. https://doi.org/10.1001/jama.2014.3

Article  CAS  PubMed  Google Scholar 

Bergonti M, Spera FR, Ferrero TG et al (2023) Characterization of atrial substrate to predict the success of pulmonary vein isolation: the prospective, multicenter MASH-AF II (Multipolar Atrial Substrate High Density Mapping in Atrial Fibrillation) Study. J Am Heart Assoc 12(1):e027795. https://doi.org/10.1161/JAHA.122.027795

Article  PubMed  Google Scholar 

Müller-Edenborn B, Moreno-Weidmann Z, Venier S et al (2022) Determinants of fibrotic atrial cardiomyopathy in atrial fibrillation. A multicenter observational study of the RETAC (reseau européen de traîtement d’arrhythmies cardiaques)-group. Clin Res Cardiol 111(9):1018–1027. https://doi.org/10.1007/s00392-021-01973-1

Article  PubMed  Google Scholar 

Kornej J, Büttner P, Sommer P et al (2019) Prediction of electro-anatomical substrate using APPLE score and biomarkers. Europace 21(1):54–59. https://doi.org/10.1093/europace/euy120

Article  PubMed  Google Scholar 

Kosiuk J, Dinov B, Kornej J et al (2015) Prospective, multicenter validation of a clinical risk score for left atrial arrhythmogenic substrate based on voltage analysis: DR-FLASH score. Heart Rhythm 12(11):2207–2212. https://doi.org/10.1016/j.hrthm.2015.07.003

Article  PubMed  Google Scholar 

Burashnikov A, Di Diego JM, Sicouri S et al (2014) A temporal window of vulnerability for development of atrial fibrillation with advancing heart failure. Eur J Heart Fail 16(3):271–280. https://doi.org/10.1002/ejhf.28

Article  PubMed  Google Scholar 

Rodríguez-Mañero M, Valderrábano M, Baluja A et al (2018) Validating left atrial low voltage areas during atrial fibrillation and atrial flutter using multielectrode automated electroanatomic mapping. JACC Clin Electrophysiol 4(12):1541–1552. https://doi.org/10.1016/j.jacep.2018.08.015

Article  PubMed  Google Scholar 

Calkins H, Hindricks G, Cappato R et al (2018) Document reviewers: 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Europace 20(1):e1–e160. https://doi.org/10.1093/europace/eux274

Article  PubMed  Google Scholar 

Kaatz S, Ahmad D, Spyropoulos AC, Schulman S (2015) Subcommittee on control of anticoagulation. Definition of clinically relevant non-major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non-surgical patients: communication from the SSC of the ISTH. J Thromb Haemost 13(11):2119–26. https://doi.org/10.1111/jth.13140

Article  CAS  PubMed  Google Scholar 

Floria M, Radu S, Gosav EM et al (2020) Left atrial structural remodelling in non-valvular atrial fibrillation: what have we learnt from CMR? Diagnostics (basel). 10(3):137. https://doi.org/10.3390/diagnostics10030137

Article  PubMed  PubMed Central  Google Scholar 

Thomas L, Marwick T, Popescu B et al (2019) Left atrial structure and function, and left ventricular diastolic dysfunction. J Am Coll Cardiol 73(15):1961–1977. https://doi.org/10.1016/j.jacc.2019.01.059

Article  PubMed  Google Scholar 

Kojodjojo P, Kanagaratnam P, Markides V, Davies DW, Peters N (2006) Age-related changes in human left and right atrial conduction. J Cardiovasc Electrophysiol 17(2):120–127. https://doi.org/10.1111/j.1540-8167.2005.00293.x

Article  PubMed  Google Scholar 

Platonov PG, Mitrofanova LB, Orshanskaya V et al (2011) Structural abnormalities in atrial walls are associated with presence and persistency of atrial fibrillation but not with age. J Am Coll Cardiol 58(21):2225–2232. https://doi.org/10.1016/j.jacc.2011.05.061

Article  PubMed  Google Scholar 

Wong GR, Nalliah CJ, Lee G, Voskoboinik A et al (2022) Sex-related differences in atrial remodeling in patients with atrial fibrillation: relationship to ablation outcomes. Circ Arrhythm Electrophysiol 15(1):e009925. https://doi.org/10.1161/CIRCEP.121.009925

Article  CAS  PubMed  Google Scholar 

Kaiser DW, Fan J, Schmitt S et al (2016) Gender differences in clinical outcomes after catheter ablation of atrial fibrillation. JACC Clin Electrophysiol 2(6):703–710. https://doi.org/10.1016/j.jacep.2016.04.014

Article  PubMed  PubMed Central  Google Scholar 

Zhang XD, Tan HW, Gu J et al (2013) Efficacy and safety of catheter ablation for long-standing persistent atrial fibrillation in women. Pacing Clin Electrophysiol 36(10):1236–1244. https://doi.org/10.1111/pace.12212

Article  PubMed  Google Scholar 

Takigawa M, Kuwahara T, Takahashi A et al (2013) Differences in catheter ablation of paroxysmal atrial fibrillation between males and females. Int J Cardiol 168(3):1984–1991. https://doi.org/10.1016/j.ijcard.2012.12.101

Article  PubMed  Google Scholar 

Patel D, Mohanty P, Di Biase L et al (2010) Outcomes and complications of catheter ablation for atrial fibrillation in females. Heart Rhythm 7(2):167–172. https://doi.org/10.1016/j.hrthm.2009.10.025

Article  PubMed  Google Scholar 

Santangeli P, di Biase L, Pelargonio G et al (2011) Outcome of invasive electrophysiological procedures and gender: are males and females the same? J Cardiovasc Electrophysiol 22(5):605–612. https://doi.org/10.1111/j.1540-8167.2010.01920.x

Article  PubMed  Google Scholar 

Humphries KH, Kerr CR, Connolly SJ et al (2001) New-onset atrial fibrillation: sex differences in presentation, treatment, and outcome. Circulation 103(19):2365–2370. https://doi.org/10.1161/01.cir.103.19.2365

Article  CAS  PubMed  Google Scholar 

Benjamin EJ, Levy D, Vaziri SM et al (1994) Independent risk factors for atrial fibrillation in a popuation-based cohort. Framingham Heart Stud JAMA 271(11):840–844

CAS  Google Scholar 

Kornej J, Hindricks G, Shoemaker MB et al (2015) The APPLE score: a novel and simple score for the prediction of rhythm outcomes after catheter ablation of atrial fibrillation. Clin Res Cardiol 104(10):871–876. https://doi.org/10.1007/s00392-015-0856-x

Article  PubMed  PubMed Central  Google Scholar 

Vogel MW, Slusser JP, Hodge DO, Chen HH (2012) The natural history of preclinical diastolic dysfunction: a population-based study. Circ Heart Fail 5(2):144–151. https://doi.org/10.1161/CIRCHEARTFAILURE.110.959668

Article  PubMed  PubMed Central  Google Scholar 

Ariyaratnam JP, Elliott AD, Mishima RS, Gallagher C, Lau DH, Sanders P (2021) Heart failure with preserved ejection fraction: an alternative paradigm to explain the clinical implications of atrial fibrillation. Heart Rhythm O2 2(6):771–783. https://doi.org/10.1016/j.hroo.2021.09.015

Article  PubMed  PubMed Central  Google Scholar 

Rolf S, Kircher S, Arya A et al (2014) Tailored atrial substrate modification based on low-voltage areas in catheter ablation of atrial fibrillation. Circ Arrhythm Electrophysiol 7(5):825–833. https://doi.org/10.1161/CIRCEP.113.001251

Article