L. Guariguata, D.R. Whiting, I. Hambleton, J. Beagley, U. Linnenkamp, J.E. Shaw, Global estimates of diabetes prevalence for 2013 and projections for 2035. Diab. Res. Clin. Pract. 103, 137–149 (2014)

Article  CAS  Google Scholar 

S. Margolis, Diabetic microvascular complications: an overview. Adv. Stud. Med. 5, S260–S263 (2005)

Google Scholar 

P. Cravedi, G. Remuzzi, Pathophysiology of proteinuria and its value as an outcome measure in chronic kidney disease. Br. J. Clin. Pharm. 76, 516–523 (2013)

Article  Google Scholar 

C.E. Mogensen, Microalbuminuria, blood pressure and diabetic renal disease: origin and development of ideas. Diabetologia 42, 263–285 (1999)

Article  CAS  PubMed  Google Scholar 

Q. Wang, H. Cheng, S. Jiang, L. Zhang, X. Liu, P. Chen, J. Liu, Y. Li, X. Liu, L. Wang, Z. Li, G. Cai, X. Chen, Z. Dong, The relationship between diabetic retinopathy and diabetic nephropathy in type 2 diabetes. Front Endocrinol. (Lausanne) 15, 1292412 (2024)

Article  PubMed  Google Scholar 

L. Xu, X. Lin, M. Guan, Y. Liu, Correlation between different stages of diabetic nephropathy and neuropathy in patients with T2DM: A cross-sectional controlled study. Diab. Ther. 9, 2335–2346 (2018)

Article  CAS  Google Scholar 

H.T. Lin, C.M. Zheng, Y.C. Wu, Y.H. Chang, J.T. Chen, C.M. Liang, T.J. Chang, J.Q. Zheng, M.C. Tai, Y.F. Lin, Diabetic retinopathy as a risk factor for chronic kidney disease progression: a multicenter case-control study in Taiwan. Nutrients 11, 509 (2019)

Article  CAS  PubMed  PubMed Central  Google Scholar 

P. Kotlarsky, A. Bolotin, K. Dorfman, B. Knyazer, T. Lifshitz, J. Levy, Link between retinopathy and nephropathy caused by complications of diabetes mellitus type 2. Int Ophthalmol. 35, 59–66 (2015)

Article  PubMed  Google Scholar 

D. Lim, D.Y. Lee, S.H. Cho, O.Z. Kim, S.W. Cho, S.K. An, H.W. Kim, K.H. Moon, M.H. Lee, B. Kim, Diagnostic accuracy of urine dipstick for proteinuria in older outpatients. Kidney Res Clin. Pract. 33, 199–203 (2014)

Article  PubMed  PubMed Central  Google Scholar 

G.L. Bakris, Slowing nephropathy progression: focus on proteinuria reduction. Clin. J. Am. Soc. Nephrol. 3, S3–S10 (2008)

Article  CAS  PubMed  PubMed Central  Google Scholar 

P. Yong, W. Hua, C. Fei, F.Y. Huang, T.L. Xia, Y.B. Liao, C. Hua, P.J. Wang, Z.L. Zuo, L. Wei, The influence of body composition on renal function in patients with coronary artery disease and its prognostic significance: a retrospective cohort study. Cardiovasc Diabetol. 15, 106 (2016)

Article  Google Scholar 

E. Imai, S. Ito, M. Haneda, A. Harada, F. Kobayashi, T. Yamasaki, H. Makino, J.C.N. Chan, Effects of blood pressure on renal and cardiovascular outcomes in Asian patients with type 2 diabetes and overt nephropathy: a post hoc analysis (ORIENT-blood pressure). Nephrol. Dial. Transpl. 31, 447–454 (2016)

Article  CAS  Google Scholar 

B.A. Perkins, L.H. Ficociello, K.H. Silva, D.M. Finkelstein, J.H. Warram, A.S. Krolewski, Regression of microalbuminuria in type 1 diabetes. N. Engl. J. Med 348, 2285–2293 (2003)

Article  CAS  PubMed  Google Scholar 

J. Lee, J.S. Lee, S.H. Park, S.A. Shin, K. Kim, Cohort profile: the national health insurance service-national sample cohort (NHIS-NSC), South Korea. Int J. Epidemiol. 46, e15 (2017)

PubMed  Google Scholar 

J.P. Fine, R.J. Gray, A proportional hazards model for the subdistribution of a competing risk. J. Am. Stat. Assoc. 94, 496–509 (1999)

Article  Google Scholar 

S. Dinesen, L. Stokholm, Y. Subhi, T. Peto, T.R. Savarimuthu, N. Andersen, J. Andresen, T. Bek, J. Hajari, S. Heegaard, K. Højlund, C.S. Laugesen, R. Kawasaki, S. Möller, K. Schielke, A.S. Thykjær, F. Pedersen, J. Grauslund, Five-year incidence of proliferative diabetic retinopathy and associated risk factors in a Nationwide Cohort of 201 945 Danish Patients with Diabetes. Ophthalmol. Sci. 3, 100291 (2023)

Article  PubMed  PubMed Central  Google Scholar 

T.Y. Wong, M. Mwamburi, R. Klein, M. Larsen, H. Flynn, M. Hernandez-Medina, G. Ranganathan, B. Wirostko, A. Pleil, P. Mitchell, Rates of progression in diabetic retinopathy during different time periods: a systematic review and meta-analysis. Diab. Care 32, 2307–2313 (2009)

Article  Google Scholar 

P. Romero-Aroca, S. de la Riva-Fernandez, A. Valls-Mateu, R. Sagarra-Alamo, A. Moreno-Ribas, N. Soler, Changes observed in diabetic retinopathy: eight-year follow-up of a Spanish population. Br. J. Ophthalmol. 100, 1366–1371 (2016)

Article  PubMed  Google Scholar 

R.L. Thomas, F. Dunstan, S.D. Luzio, S. Roy Chowdury, S.L. Hale, R.V. North, R.L. Gibbins, D.R. Owens, Incidence of diabetic retinopathy in people with type 2 diabetes mellitus attending the Diabetic Retinopathy Screening Service for Wales: retrospective analysis. BMJ 344, e874 (2012)

Article  CAS  PubMed  PubMed Central  Google Scholar 

C.D. Jones, R.H. Greenwood, A. Misra, M.O. Bachmann, Incidence and progression of diabetic retinopathy during 17 years of a population-based screening program in England. Diab. Care 35, 592–596 (2012)

Article  Google Scholar 

C.W. Hicks, E. Selvin, Epidemiology of peripheral neuropathy and lower extremity disease in diabetes. Curr. Diab Rep. 19, 86 (2019)

Article  PubMed  PubMed Central  Google Scholar 

M.R. Manaviat, M. Afkhami, M.R. Shoja, Retinopathy and microalbuminuria in type II diabetic patients. BMC Ophthalmol. 4, 9 (2004)

Article  PubMed  PubMed Central  Google Scholar 

Y.H. Chen, H.S. Chen, D.C. Tarng, More impact of microalbuminuria on retinopathy than moderately reduced GFR among type 2 diabetic patients. Diab. Care 35, 803–808 (2012)

Article  CAS  Google Scholar 

P.K. Rani, R. Raman, A. Gupta, S.S. Pal, V. Kulothungan, T. Sharma, Albuminuria and diabetic retinopathy in type 2 diabetes mellitus sankara nethralaya diabetic retinopathy epidemiology and molecular genetic study (SN-DREAMS, report 12). Diabetol. Metab. Syndr. 3, 9 (2011)

Article  CAS  PubMed  PubMed Central  Google Scholar 

S. Chawla, S. Trehan, A. Chawla, S. Jaggi, R. Chawla, V. Kumar, D. Singh, Relationship between diabetic retinopathy microalbuminuria and other modifiable risk factors. Prim. Care Diab. 15, 567–570 (2021)

Article  CAS  Google Scholar 

Y. Zhang, Y. Jiang, X. Shen, S. Yan, Can both normal and mildly abnormal albuminuria and glomerular filtration rate be a danger signal for diabetic peripheral neuropathy in type 2 diabetes mellitus? Neurol. Sci. 38, 1381–1390 (2017)

Article  PubMed  Google Scholar 

G.R. Debele, S.A. Kuse, B.T. Kefeni, A. Geda, W.W. Jifar, K.M. Kitila, M. Hajure, Why too soon? Predictors of time to diabetic peripheral neuropathy among newly diagnosed diabetes mellitus patients: a multicenter follow-up study at health-care setting of Ethiopia. Arch. Public Health 81, 186 (2023)

Article  PubMed  PubMed Central  Google Scholar 

T. Muramatsu, M. Takahashi, R. Kakinuma, T. Sato, M. Yamamoto, M. Akazawa, K. Tanaka, T. Kikuchi, A. Kushiyama, Decline in renal function associated with cardiovascular autonomic neuropathy positively coordinated with proteinuria in patients with type 2 diabetes. J. Diab. Investig. 13, 102–111 (2022)

Article  CAS  Google Scholar 

A. Wang, Y. Sun, X. Liu, Z. Su, J. Li, Y. Luo, S. Chen, J. Wang, X. Li, Z. Zhao, H. Zhu, S. Wu, X. Guo, Changes in proteinuria and the risk of myocardial infarction in people with diabetes or pre-diabetes: a prospective cohort study. Cardiovasc Diabetol. 16, 104 (2017)

Article  PubMed  PubMed Central  Google Scholar 

Y. Sun, A. Wang, X. Liu, Z. Su, J. Li, Y. Luo, S. Chen, J. Wang, X. Li, Z. Zhao, H. Zhu, S. Wu, X. Guo, Changes in proteinuria on the risk of all-cause mortality in people with diabetes or prediabetes: a prospective cohort study. J. Diab. Res 2017, 8368513 (2017)

Google Scholar 

A. Wang, L. Dai, Z. Su, S. Chen, J. Li, S. Wu, Y. Wang, Y. Wang, Proteinuria and risk of stroke in patients with hypertension: The Kailuan cohort study. J. Clin. Hypertens. (Greenwich) 20, 765–774 (2018)

Article  PubMed  Google Scholar 

K. Tryggvason, E. Pettersson, Causes and consequences of proteinuria: the kidney filtration barrier and progressive renal failure. J. Intern Med. 254, 216–224 (2003)

Article  CAS  PubMed  Google Scholar 

R.J.H. Martens, A.J.H.M. Houben, J.P. Kooman, T.T.J.M. Berendschot, P.C. Dagnelie, C.J.H. van der Kallen, A.A. Kroon, K.M.L. Leunissen, F.M. van der Sande, N.C. Schaper, J.S.A.G. Schouten, M.T. Schram, S.J.S. Sep, B.M. Sörensen, R.M.A. Henry, C.D.A. Stehouwer, Microvascular endothelial dysfunction is associated with albuminuria: the Maastricht Study. J. Hypertens. 36, 1178–1187 (2018)

Article  CAS