Taylor VC, Buckley CD, Douglas M, Cody AJ, Simmons DL, Freeman SD. The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2. J Biol Chem. 1999;274(17):11505–12. https://doi.org/10.1074/jbc.274.17.11505.
Article CAS PubMed Google Scholar
Legrand O, Perrot JY, Baudard M, Cordier A, Lautier R, Simonin G, et al. The immunophenotype of 177 adults with acute myeloid leukemia: proposal of a prognostic score. Blood. 2000;96(3):870–7.
Article CAS PubMed Google Scholar
Jilani I, Estey E, Huh Y, Joe Y, Manshouri T, Yared M, et al. Differences in CD33 intensity between various myeloid neoplasms. Am J Clin Pathol. 2002;118(4):560–6. https://doi.org/10.1309/1WMW-CMXX-4WN4-T55U.
Sievers EL, Larson RA, Stadtmauer EA, Estey E, Lowenberg B, Dombret H, et al. Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse. J Clin Oncol. 2001;19(13):3244–54. https://doi.org/10.1200/jco.2001.19.13.3244.
Article CAS PubMed Google Scholar
Castaigne S, Pautas C, Terre C, Raffoux E, Bordessoule D, Bastie JN, et al. Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study. Lancet (London, England). 2012;379(9825):1508–16. https://doi.org/10.1016/s0140-6736(12)60485-1.
Article CAS PubMed Google Scholar
Appelbaum FR, Bernstein ID. Gemtuzumab ozogamicin for acute myeloid leukemia. Blood. 2017;130(22):2373–6. https://doi.org/10.1182/blood-2017-09-797712.
Article CAS PubMed Google Scholar
Lamba JK, Pounds S, Cao X, Downing JR, Campana D, Ribeiro RC, et al. Coding polymorphisms in CD33 and response to gemtuzumab ozogamicin in pediatric patients with AML: a pilot study. Leukemia. 2009;23(2):402–4. https://doi.org/10.1038/leu.2008.185.
Article CAS PubMed Google Scholar
Malik M, Simpson JF, Parikh I, Wilfred BR, Fardo DW, Nelson PT, et al. CD33 Alzheimer’s risk-altering polymorphism, CD33 expression, and exon 2 splicing. J Neurosci. 2013;33(33):13320–5. https://doi.org/10.1523/jneurosci.1224-13.2013.
Article CAS PubMed PubMed Central Google Scholar
Hamann PR, Hinman LM, Hollander I, Beyer CF, Lindh D, Holcomb R, et al. Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia. Bioconjug Chem. 2002;13(1):47–58. https://doi.org/10.1021/bc010021y.
Article CAS PubMed Google Scholar
Mortland L, Alonzo TA, Walter RB, Gerbing RB, Mitra AK, Pollard JA, et al. Clinical significance of CD33 nonsynonymous single-nucleotide polymorphisms in pediatric patients with acute myeloid leukemia treated with gemtuzumab-ozogamicin–containing chemotherapy. Clin Cancer Res. 2013;19(6):1620–7.
Article CAS PubMed PubMed Central Google Scholar
Malik M, Chiles J 3rd, Xi HS, Medway C, Simpson J, Potluri S, et al. Genetics of CD33 in Alzheimer’s disease and acute myeloid leukemia. Hum Mol Genet. 2015;24(12):3557–70. https://doi.org/10.1093/hmg/ddv092.
Article CAS PubMed PubMed Central Google Scholar
Lamba JK, Chauhan L, Shin M, Loken MR, Pollard JA, Wang YC, et al. CD33 splicing polymorphism determines gemtuzumab ozogamicin response in de novo acute myeloid leukemia: report from randomized phase III children’s oncology group trial AAML0531. J Clin Oncol. 2017;35(23):2674–82. https://doi.org/10.1200/jco.2016.71.2513.
Article CAS PubMed PubMed Central Google Scholar
Teich K, Krzykalla J, Kapp-Schwoerer S, Gaidzik VI, Schlenk RF, Paschka P, et al. Cluster of differentiation 33 single nucleotide polymorphism rs12459419 is a predictive factor in patients with nucleophosmin1-mutated acute myeloid leukemia receiving gemtuzumab ozogamicin. Haematologica. 2021;106(11):2986–9. https://doi.org/10.3324/haematol.2021.278894.
Article PubMed PubMed Central Google Scholar
Gale RE, Popa T, Wright M, Khan N, Freeman SD, Burnett AK, et al. No evidence that CD33 splicing SNP impacts the response to GO in younger adults with AML treated on UK MRC/NCRI trials. Blood. 2018;131(4):468–71. https://doi.org/10.1182/blood-2017-08-802157.
Article CAS PubMed Google Scholar
Short NJ, Richard-Carpentier G, Kanagal-Shamanna R, Patel KP, Konopleva M, Papageorgiou I, et al. Impact of CD33 and ABCB1 single nucleotide polymorphisms in patients with acute myeloid leukemia and advanced myeloid malignancies treated with decitabine plus gemtuzumab ozogamicin. Am J Hematol. 2020;95(9):E225–8. https://doi.org/10.1002/ajh.25854.
Article CAS PubMed Google Scholar
Castano-Bonilla T, Barragan E, Sargas C, Sanz A, Algarra L, Herrera-Puente P, et al. No Evidence that CD33 rs12459419 polymorphism predicts gemtuzumab ozogamicin response in consolidation treatment of acute myeloid leukemia patients: experience of the PETHEMA Group. Dis Markers. 2022;2022:3132941. https://doi.org/10.1155/2022/3132941.
Article CAS PubMed PubMed Central Google Scholar
Laszlo GS, Beddoe ME, Godwin CD, Bates OM, Gudgeon CJ, Harrington KH, et al. Relationship between CD33 expression, splicing polymorphism, and in vitro cytotoxicity of gemtuzumab ozogamicin and the CD33/CD3 BiTE(R) AMG 330. Haematologica. 2019;104(2):e59–62. https://doi.org/10.3324/haematol.2018.202069.
Article CAS PubMed PubMed Central Google Scholar
Lamba JK, Meshinchi S. Time to reconsider CD33 single nucleotide polymorphism in the response to gemtuzumab ozogamicin. Haematologica. 2021;106(11):2796–8. https://doi.org/10.3324/haematol.2021.279043.
Article PubMed PubMed Central Google Scholar
Morishige S, Mizuno S, Ozawa H, Nakamura T, Mazahery A, Nomura K, et al. CRISPR/Cas9-mediated gene correction in hemophilia B patient-derived iPSCs. Int J Hematol. 2020;111(2):225–33. https://doi.org/10.1007/s12185-019-02765-0.
Article CAS PubMed Google Scholar
Nakamura T, Morishige S, Ozawa H, Kuboyama K, Yamasaki Y, Oya S, et al. Successful correction of factor V deficiency of patient-derived iPSCs by CRISPR/Cas9-mediated gene editing. Haemophilia. 2020;26(5):826–33. https://doi.org/10.1111/hae.14104.
Article CAS PubMed Google Scholar
Perez-Oliva AB, Martinez-Esparza M, Vicente-Fernandez JJ, Corral-San Miguel R, Garcia-Penarrubia P, Hernandez-Caselles T. Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells. Glycobiology. 2011;21(6):757–70. https://doi.org/10.1093/glycob/cwq220.
Article CAS PubMed Google Scholar
Kanda Y. Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplant. 2013;48(3):452–8. https://doi.org/10.1038/bmt.2012.244.
Article CAS PubMed Google Scholar
Shaw BC, Estus S. Pseudogene-mediated gene conversion after CRISPR-Cas9 editing demonstrated by partial CD33 conversion with SIGLEC22P. CRISPR J. 2021;4(5):699–709. https://doi.org/10.1089/crispr.2021.0052.
Article CAS PubMed PubMed Central Google Scholar
Godwin CD, Laszlo GS, Wood BL, Correnti CE, Bates OM, Garling EE, et al. The CD33 splice isoform lacking exon 2 as therapeutic target in human acute myeloid leukemia. Leukemia. 2020;34(9):2479–83. https://doi.org/10.1038/s41375-020-0755-7.
Article PubMed PubMed Central Google Scholar
Gbadamosi MO, Shastri VM, Hylkema T, Papageorgiou I, Pardo L, Cogle CR, et al. Novel CD33 antibodies unravel localization, biology and therapeutic implications of CD33 isoforms. Future Oncol (London, England). 2021;17(3):263–77. https://doi.org/10.2217/fon-2020-0746.
Siddiqui SS, Springer SA, Verhagen A, Sundaramurthy V, Alisson-Silva F, Jiang W, et al. The Alzheimer’s disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool. J Biol Chem. 2017;292(37):15312–20. https://doi.org/10.1074/jbc.M117.799346.
留言 (0)