Yndigegn T, Hofmann R, Jernberg T, Gale CP. Registry-based randomised clinical trial: efficient evaluation of generic pharmacotherapies in the contemporary era. Heart (British Cardiac Society). 2018;104(19):1562–7.

PubMed  Google Scholar 

Bergqvist D, Björck M, Säwe J, Troëng T. Randomized trials or population-based registries. Eur J Vasc Endovasc Surg. 2007;34(3):253–6.

Article  CAS  PubMed  Google Scholar 

Asberg S, Hijazi Z, Norrving B, Terent A, Ohagen P, Oldgren J. Timing of oral anticoagulant therapy in acute ischemic stroke with atrial fibrillation: study protocol for a registry-based randomised controlled trial. Trials. 2017;18(1):581.

Article  PubMed  PubMed Central  Google Scholar 

Ragnarsson S, Janiec M, Modrau IS, Dreifaldt M, Ericsson A, Holmgren A, et al. No-touch saphenous vein grafts in coronary artery surgery (SWEDEGRAFT): rationale and design of a multicenter, prospective, registry-based randomised clinical trial. Am Heart J. 2020;224:17–24.

Article  PubMed  Google Scholar 

Frobert O, Lagerqvist B, Gudnason T, Thuesen L, Svensson R, Olivecrona GK, et al. Thrombus Aspiration in ST-Elevation myocardial infarction in Scandinavia (TASTE trial). A multicenter, prospective, randomised, controlled clinical registry trial based on the Swedish angiography and angioplasty registry (SCAAR) platform. Study design and rationale. Am Heart J. 2010;160(6):1042–8.

Article  PubMed  Google Scholar 

James S, Rao SV, Granger CB. Registry-based randomised clinical trials–a new clinical trial paradigm. Nat Rev Cardiol. 2015;12(5):312–6.

Article  PubMed  Google Scholar 

Li G, Sajobi TT, Menon BK, Korngut L, Lowerison M, James M, et al. Registry-based randomised controlled trials- what are the advantages, challenges, and areas for future research? J Clin Epidemiol. 2016;80:16–24.

Article  PubMed  Google Scholar 

Fröbert O, Lagerqvist B, Olivecrona GK, Omerovic E, Gudnason T, Maeng M, et al. Thrombus aspiration during ST-segment elevation myocardial infarction. N Engl J Med. 2013;369(17):1587–97.

Article  PubMed  Google Scholar 

Sacristán JA, Soto J, Galende I, Hylan TR. Randomized database studies: a new method to assess drugs’ effectiveness? J Clin Epidemiol. 1998;51(9):713–5.

PubMed  Google Scholar 

van Staa TP, Dyson L, McCann G, Padmanabhan S, Belatri R, Goldacre B, et al. The opportunities and challenges of pragmatic point-of-care randomised trials using routinely collected electronic records: evaluations of two exemplar trials. Health Technol Assess. 2014;18(43):1–146.

PubMed  PubMed Central  Google Scholar 

Bibby AC, Torgerson DJ, Leach S, Lewis-White H, Maskell NA. Commentary: considerations for using the “Trials within Cohorts” design in a clinical trial of an investigational medicinal product. Trials. 2018;19(1):18.

Article  PubMed  PubMed Central  Google Scholar 

Mathes T, Buehn S, Prengel P, Pieper D. Registry-based randomised controlled trials merged the strength of randomised controlled trails and observational studies and give rise to more pragmatic trials. J Clin Epidemiol. 2018;93:120–7.

Article  PubMed  Google Scholar 

Kwakkenbos L, Imran M, McCall SJ, McCord KA, Fröbert O, Hemkens LG, et al. CONSORT extension for the reporting of randomised controlled trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE): checklist with explanation and elaboration. BMJ. 2021;373:n857.

Article  PubMed  PubMed Central  Google Scholar 

Karanatsios B, Prang KH, Verbunt E, Yeung JM, Kelaher M, Gibbs P. Defining key design elements of registry-based randomised controlled trials: a scoping review. Trials. 2020;21(1):552.

Article  PubMed  PubMed Central  Google Scholar 

Christiansen EH, Jensen LO, Thayssen P, Tilsted HH, Krusell LR, Hansen KN, et al. Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non- inferiority trial. Lancet. 2013;381(9867):661–9.

Article  CAS  PubMed  Google Scholar 

Katapodi MC, Northouse LL, Schafenacker AM, Duquette D, Duffy SA, Ronis DL, et al. Using a state cancer registry to recruit young breast cancer survivors and high-risk relatives: protocol of a randomised trial testing the efficacy of a targeted versus a tailored intervention to increase breast cancer screening. BMC Cancer. 2013;13:97.

Article  PubMed  PubMed Central  Google Scholar 

Sundh J, Bornefalk-Hermansson A, Ahmadi Z, Blomberg A, Janson C, Currow DC, et al. REgistry-based randomised controlled trial of treatment and Duration and mortality in long-term OXygen therapy (REDOX) study protocol. BMC Pulm Med. 2019;19(1):50.

Article  PubMed  PubMed Central  Google Scholar 

Idahl A, Darelius A, Sundfeldt K, Pålsson M, Strandell A. Hysterectomy and opportunistic salpingectomy (HOPPSA): study protocol for a register-based randomised controlled trial. Trials. 2019;20(1):10.

Article  PubMed  PubMed Central  Google Scholar 

Drolet BC, Johnson KB. Categorizing the world of registries. J Biomed Inform. 2008;41(6):1009–20.

Article  PubMed  Google Scholar 

Gliklich RE, Dreyer NA, Leavy MB. Registries for evaluating patient outcomes: a user’s guide. 2014.

Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan-a web and mobile app for systematic reviews. Syst Rev. 2016;5(1):210.

Article  PubMed  PubMed Central  Google Scholar 

Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.

Article  PubMed  PubMed Central  Google Scholar 

Popay J, Roberts H, Sowden A, Petticrew M, Arai L, Rodgers M, et al. Guidance on the conduct of narrative synthesis in systematic reviews. A product from the ESRC methods programme Version. 2006;1:b92.

Google Scholar 

Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.

Article  PubMed  PubMed Central  Google Scholar 

Erlinge D, Omerovic E, Frobert O, Linder R, Danielewicz M, Hamid M, et al. Bivalirudin versus heparin monotherapy in myocardial infarction. N Engl J Med. 2017;377(12):1132–42.

Article  CAS  PubMed  Google Scholar 

Trivedi DP, Doll R, Khaw KT. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ. 2003;326(7387):469.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Young PJ, Bagshaw SM, Forbes AB, Nichol AD, Wright SE, Bailey M, et al. Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital mortality among ICU patients receiving invasive mechanical ventilation: the PEPTIC randomized clinical trial. JAMA. 2020;323(7):616–26.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Götberg M, Christiansen EH, Gudmundsdottir IJ, Sandhall L, Danielewicz M, Jakobsen L, et al. Instantaneous wave-free ratio versus fractional flow reserve to guide PCI. N Engl J Med. 2017;376(19):1813–23.

Article  PubMed  Google Scholar 

Hofmann R, Svensson L, James SK. Oxygen therapy in suspected acute myocardial infarction. N Engl J Med. 2018;378(2):201–2.

PubMed  Google Scholar 

Navaneethan SD, Jolly SE, Schold JD, Arrigain S, Nakhoul G, Konig V, et al. Pragmatic randomized, controlled trial of patient navigators and enhanced personal health records in CKD. Clinical journal of the American Society of Nephrology : CJASN. 2017;12(9):1418–27.

Article  PubMed  PubMed Central  Google Scholar 

Chamany S, Walker EA, Schechter CB, Gonzalez JS, Davis NJ, Ortega FM, et al. Telephone intervention to improve diabetes control: a randomized trial in the New York City A1c registry. Am J Prev Med. 2015;49(6):832–41.

Article  PubMed  PubMed Central  Google Scholar 

Eccles MP, Whitty PM, Speed C, Steen IN, Vanoli A, Hawthorne GC, et al. A pragmatic cluster randomised controlled trial of a Diabetes REcall And Management system: the DREAM trial. Implement Sci. 2007;2:6.

Article  PubMed  PubMed Central  Google Scholar 

Dombkowski KJ, Costello LE, Harrington LB, Dong S, Kolasa M, Clark SJ. Age-specific strategies for immunization re