Mehrabi A, Kashfi A, Fonouni H, Schemmer P, Schmied BM, Hallscheidt P, et al. Primary malignant hepatic epithelioid hemangioendothelioma: a comprehensive review of the literature with emphasis on the surgical therapy. Cancer. 2006;107(9):2108–21.

Article  PubMed  Google Scholar 

Thin LW, Wong DD, De Boer BW, Ferguson JM, Adams L, Macquillan G, et al. Hepatic epithelioid haemangioendothelioma: challenges in diagnosis and management. Intern Med J. 2010;40(10):710–5.

Article  CAS  PubMed  Google Scholar 

Mascarelli PE, Iredell JR, Maggi RG, Weinberg G, Breitschwerdt EB. Bartonella species bacteremia in two patients with epithelioid hemangioendothelioma. J Clin Microbiol. 2011;49(11):4006–12.

Article  PubMed  PubMed Central  Google Scholar 

Treska V, Daum O, Svajdler M, Liska V, Ferda J, Baxa J. Hepatic epithelioid hemangioendothelioma: a rare tumor and diagnostic dilemma. In Vivo. 2017;31(4):763–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gan LU, Chang R, Jin H, Yang LI. Typical CT and MRI signs of hepatic epithelioid hemangioendothelioma. Oncol Lett. 2016;11(3):1699–706.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shibuya R, Matsuyama A, Shiba E, Harada H, Yabuki K, Hisaoka M. CAMTA1 is a useful immunohistochemical marker for diagnosing epithelioid haemangioendothelioma. Histopathology. 2015;67(6):827–35.

Article  PubMed  Google Scholar 

Kawka M, Mak S, Qiu S, Gall TMH, Jiao LR. Hepatic epithelioid hemangioendothelioma (HEHE)-rare vascular malignancy mimicking cholangiocarcinoma: a case report. Transl Gastroenterol Hepatol. 2022;7:42.

Article  PubMed  PubMed Central  Google Scholar 

Calabro L, Di Giacomo AM, Altomonte M, Fonsatti E, Mazzei MA, Volterrani L, et al. Primary hepatic epithelioid hemangioendothelioma progressively responsive to interferon-alpha: is there room for novel anti-angiogenetic treatments? J Exp Clin Cancer Res. 2007;26(1):145–50.

CAS  PubMed  Google Scholar 

Galvao FH, Bakonyi-Neto A, Machado MA, Farias AQ, Mello ES, Diz ME, Machado MC. Interferon alpha-2B and liver resection to treat multifocal hepatic epithelioid hemangioendothelioma: a relevant approach to avoid liver transplantation. Transpl Proc. 2005;37(10):4354–8.

Article  CAS  Google Scholar 

Roudier-Pujol C, Enjolras O, Lacronique J, Guillemette J, Herbreteau D, Leibowitch M, Escande JP. Multifocal epithelioid hemangioendothelioma with partial remission after interferon alfa-2a treatment. Ann Dermatol Venereol. 1994;121(12):898–904.

CAS  PubMed  Google Scholar 

Sangro B, Inarrairaegui M, Fernandez-Ros N. Malignant epithelioid hemangioendothelioma of the liver successfully treated with Sorafenib. Rare Tumors. 2012;4(2):e34.

Article  PubMed  PubMed Central  Google Scholar 

Ahmed M, Solbiati L, Brace CL, Breen DJ, Callstrom MR, Charboneau JW, et al. Image-guided tumor ablation: standardization of terminology and reporting criteria: a 10-year update. Radiology. 2014;273(1):241–60.

Article  PubMed  Google Scholar 

Hu EY, Bhagavatula SK, Shi A, Merriam P, Levesque VM, Shyn PB. Image-guided percutaneous ablation of hepatic epithelioid hemangioendothelioma. Abdom Radiol. 2024;49:1241–7.

Article  Google Scholar 

Wang LR, Zhou JM, Zhao YM, He HW, Chai ZT, Wang M, et al. Clinical experience with primary hepatic epithelioid hemangioendothelioma: retrospective study of 33 patients. World J Surg. 2012;36(11):2677–83.

Article  PubMed  Google Scholar 

Karaman B, Battal B, Alagoz E, Akgun V, Ince S, Ustunsoz B. Complete disappearance of uptake of FDG in the multifocal liver hemangioendothelioma after radioembolization therapy using yttrium-90 microspheres. Ann Nucl Med. 2012;26(5):440–3.

Article  CAS  PubMed  Google Scholar 

Narayanan G. Irreversible electroporation. Semin Intervent Radiol. 2015;32(4):349–55.

Article  PubMed  PubMed Central  Google Scholar 

Thomson KR, Cheung W, Ellis SJ, Federman D, Kavnoudias H, Loader-Oliver D, et al. Investigation of the safety of irreversible electroporation in humans. J Vasc Interv Radiol. 2011;22(5):611–21.

Article  PubMed  Google Scholar 

Neal RE 2nd, Kavnoudias H, Cheung W, Golebiowski B, McLean CA, Thomson KR. Hepatic epithelioid hemangioendothelioma treated with irreversible electroporation and antibiotics. J Clin Oncol. 2013;31(27):e422–6.

Article  PubMed  Google Scholar 

Tong D, Constantinidou A, Engelmann B, Chamberlain F, Thway K, Fisher C, et al. The role of local therapy in multi-focal epithelioid haemangioendothelioma. Anticancer Res. 2019;39(9):4891–6.

Article  PubMed  Google Scholar 

Kou K, Chen YG, Zhou JP, Sun XD, Sun DW, Li SX, Lv GY. Hepatic epithelioid hemangioendothelioma: update on diagnosis and therapy. World J Clin Cases. 2020;8(18):3978–87.

Article  PubMed  PubMed Central  Google Scholar 

von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP, Initiative S. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol. 2008;61(4):344–9.

Article  Google Scholar 

Crocetti L, de Baere T, Lencioni R. Quality improvement guidelines for radiofrequency ablation of liver tumours. Cardiovasc Intervent Radiol. 2010;33(1):11–7.

Article  PubMed  Google Scholar 

Fournier L, Ammari S, Thiam R, Cuenod CA. Imaging criteria for assessing tumour response: RECIST, mRECIST. Cheson Diagn Interv Imaging. 2014;95(7–8):689–703.

Article  CAS  PubMed  Google Scholar 

Puijk RS, Ahmed M, Adam A, Arai Y, Arellano R, de Baere T, et al. Consensus guidelines for the definition of time-to-event end points in image-guided tumor ablation: results of the SIO and DATECAN initiative. Radiology. 2021;301(3):533–40.

Article  PubMed  Google Scholar 

Common Terminology Criteria for Adverse Events (CTCAE) v5.0 2017 [Available from: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf.

Madariaga JR, Marino IR, Karavias DD, Nalesnik MA, Doyle HR, Iwatsuki S, et al. Long-term results after liver transplantation for primary hepatic epithelioid hemangioendothelioma. Ann Surg Oncol. 1995;2(6):483–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nudo CG, Yoshida EM, Bain VG, Marleau D, Wong P, Marotta PJ, et al. Liver transplantation for hepatic epithelioid hemangioendothelioma: the Canadian multicentre experience. Can J Gastroenterol. 2008;22(10):821–4.

Article  PubMed  PubMed Central  Google Scholar 

Fukuhara S, Tahara H, Hirata Y, Ono K, Hamaoka M, Shimizu S, et al. Hepatic epithelioid hemangioendothelioma successfully treated with living donor liver transplantation: a case report and literature review. Clin Case Rep. 2020;8(1):108–15.

Article  PubMed  Google Scholar 

Lauffer JM, Zimmermann A, Krahenbuhl L, Triller J, Baer HU. Epithelioid hemangioendothelioma of the liver. A rare hepatic tumor Cancer. 1996;78(11):2318–27.

CAS  PubMed  Google Scholar 

Ben-Haim M, Roayaie S, Ye MQ, Thung SN, Emre S, Fishbein TA, et al. Hepatic epithelioid hemangioendothelioma: resection or transplantation, which and when? Liver Transpl Surg. 1999;5(6):526–31.

Article  CAS  PubMed  Google Scholar 

Bally O, Tassy L, Richioud B, Decouvelaere AV, Blay JY, Derbel O. Eight years tumor control with pazopanib for a metastatic resistant epithelioid hemangioendothelioma. Clin Sarcoma Res. 2015;5:12.

Article  PubMed  PubMed Central  Google Scholar 

Mascarenhas RC, Sanghvi AN, Friedlander L, Geyer SJ, Beasley HS, Van Thiel DH. Thalidomide inhibits the growth and progression of hepatic epithelioid hemangioendothelioma. Oncology. 2004;67(5–6):471–5.

Article  PubMed  Google Scholar 

Kingham TP, Karkar AM, D’Angelica MI, Allen PJ, Dematteo RP, Getrajdman GI, et al. Ablation of perivascular hepatic malignant tumors with irreversible electroporation. J Am Coll Surg. 2012;215(3):379–87.

Article  PubMed