Chamoli A, Gosavi AS, Shirwadkar UP, Wangdale KV, Behera SK, Kurrey NK, et al. Overview of oral cavity squamous cell carcinoma: risk factors, mechanisms, and diagnostics. Oral Oncol. 2021;121: 105451.
Das C, Dash SR, Sinha S, Paul S, Das B, Bhal S, et al. Talazoparib enhances the quinacrine-mediated apoptosis in patient-derived oral mucosa CSCs by inhibiting BER pathway through the modulation of GCN5 and P300. Med Oncol. 2023;40:351.
Article CAS PubMed Google Scholar
Bhal S, Kundu CN. Targeting crosstalk of signaling pathways in cancer stem cells: a promising approach for development of novel anti-cancer therapeutics. Med Oncol. 2023;40:82.
Kuang Y, Kang J, Li H, Liu B, Zhao X, Li L, et al. Multiple functions of p21 in cancer radiotherapy. J Cancer Res Clin Oncol. 2021;147:987–1006.
Article CAS PubMed Google Scholar
Yoshida H, Yoshimura H, Matsuda S, Yamamoto S, Ohmori M, Ohta K, et al. Celecoxib suppresses lipopolysaccharide-stimulated oral squamous cell carcinoma proliferation in vitro and in vivo. Oncol Lett. 2019;18:5793–800.
CAS PubMed PubMed Central Google Scholar
Huang YC, Lee PC, Wang JJ, Hsu YC. Anticancer effect and mechanism of hydroxygenkwanin in oral squamous cell carcinoma. Front Oncol. 2019;9:911.
Article PubMed PubMed Central Google Scholar
Wang TH, Chen CC, Leu YL, Lee YS, Lian JH, Hsieh HL, et al. Palbociclib induces DNA damage and inhibits DNA repair to induce cellular senescence and apoptosis in oral squamous cell carcinoma. J Formos Med Assoc. 2021;120:1695–705.
Article CAS PubMed Google Scholar
Mohapatra P, Satapathy SR, Das D, Siddharth S, Choudhuri T, Kundu CN. Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of long patch base excision repair pathway. Toxicol Appl Pharmacol. 2014;275:221–31.
Article CAS PubMed Google Scholar
Song L, Li Z-Y, Liu W-P, Zhao M-R. Crosstalk between Wnt/β-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy. Cancer Biol Ther. 2015;16:1–7.
Article PubMed PubMed Central Google Scholar
Devgan V, Mammucari C, Millar SE, Brisken C, Dotto GP. p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev. 2005;19:1485–95.
Article CAS PubMed PubMed Central Google Scholar
Geng Y, Liu J, Xie Y, Jiang H, Zuo K, Li T, et al. Trichostatin A promotes GLI1 degradation and P21 expression in multiple myeloma cells. Cancer Manag Res. 2018. https://doi.org/10.2147/CMAR.S167330.
Article PubMed PubMed Central Google Scholar
Mohapatra P, Satapathy SR, Siddharth S, Das D, Nayak A, Kundu CN. Resveratrol and curcumin synergistically induces apoptosis in cigarette smoke condensate transformed breast epithelial cells through a p21Waf1/Cip1 mediated inhibition of Hh-Gli signaling. Int J Biochem Cell Biol. 2015;66:75–84.
Article CAS PubMed Google Scholar
Farooqi AA, Shu CW, Huang HW, Wang HR, Chang YT, Fayyaz S, et al. TRAIL, Wnt, sonic hedgehog, TGFβ, and miRNA signalings are potential targets for oral cancer therapy. Int J Mol Sci. 2017;18:1523.
Article PubMed PubMed Central Google Scholar
Xie J, Huang L, Lu YG, Zheng DL. Roles of the Wnt signaling pathway in head and neck squamous cell carcinoma. Front Mol Biosci. 2021;7:590912.
Article PubMed PubMed Central Google Scholar
Liao X, Siu MK, Au CW, Chan QK, Chan HY, Wong ES, et al. Aberrant activation of hedgehog signaling pathway contributes to endometrial carcinogenesis through β-catenin. Mod Pathol. 2009;22:839–47.
Article CAS PubMed Google Scholar
Zhang X, Zhang C, Ren Z, Zhang F, Xu J, Zhang X, et al. Curcumin affects gastric cancer cell migration, invasion and cytoskeletal remodeling through gli1-β-catenin. Cancer Manag Res. 2020. https://doi.org/10.2147/CMAR.S244384.
Article PubMed PubMed Central Google Scholar
Nayak A, Siddharth S, Das S, Nayak D, Sethy C, Kundu CN. Nanoquinacrine caused apoptosis in oral cancer stem cells by disrupting the interaction between GLI1 and β catenin through activation of GSK3β. Toxicol Appl Pharmacol. 2017;330:53–64.
Article CAS PubMed Google Scholar
Zinke J, Schneider FT, Harter PN, Thom S, Ziegler N, Toftgård R, et al. β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma. Mol Cancer. 2015;14:1–9.
Akiyoshi T, Nakamura M, Koga K, Nakashima H, Yao T, Tsuneyoshi M, et al. Gli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activation. Gut. 2006;55:991–9.
Article CAS PubMed PubMed Central Google Scholar
Takebe N, Harris PJ, Warren RQ, Ivy SP. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol. 2011;8:97–106.
Article CAS PubMed Google Scholar
Pradhan R, Chatterjee S, Hembram KC, Sethy C, Mandal M, Kundu CN. Nano formulated Resveratrol inhibits metastasis and angiogenesis by reducing inflammatory cytokines in oral cancer cells by targeting tumor associated macrophages. J Nutr Biochem. 2021;92:108624.
Article CAS PubMed Google Scholar
Yuan L, Zhang Y, Xia J, Liu B, Zhang Q, Liu J, et al. Resveratrol induces cell cycle arrest via a p53-independent pathway in A549 cells. Mol Med Rep. 2015;11:2459–64.
Article CAS PubMed Google Scholar
Liao PC, Ng LT, Lin LT, Richardson CD, Wang GH, Lin CC. Resveratrol arrests cell cycle and induces apoptosis in human hepatocellular carcinoma Huh-7 cells. J Med Food. 2010;13:1415–23.
Article CAS PubMed Google Scholar
Mohapatra P, Preet R, Das D, Satapathy SR, Choudhuri T, Wyatt MD, et al. Quinacrine-mediated autophagy and apoptosis in colon cancer cells is through a p53-and p21-dependent mechanism. Oncol Res. 2012;20:81–91.
Dash SR, Chatterjee S, Sinha S, Das B, Paul S, Pradhan R, et al. NIR irradiation enhances the apoptotic potentiality of quinacrine-gold hybrid nanoparticles by modulation of HSP-70 in oral cancer stem cells. Nanomedicine. 2022. https://doi.org/10.1016/j.nano.2021.102502.
Hembram KC, Dash SR, Das B, Sethy C, Chatterjee S, Bindhani BK, et al. Quinacrine based gold hybrid nanoparticles caused apoptosis through modulating replication fork in oral cancer stem cells. Mol Pharm. 2020;17:2463–72.
Article CAS PubMed Google Scholar
Das B, Dash SR, Patel H, Sinha S, Bhal S, Paul S, et al. Quinacrine inhibits HIF-1α/VEGF-A mediated angiogenesis by disrupting the interaction between cMET and ABCG2 in patient-derived breast cancer stem cells. Phytomedicine. 2023;117:154914.
Article CAS PubMed Google Scholar
Nayak D, Paul S, Das C, Bhal S, Kundu CN. Quinacrine and Curcumin in combination decreased the breast cancer angiogenesis by modulating ABCG2 via VEGF A. J Cell Commun Signal. 2023;17:609–26.
Article CAS PubMed Google Scholar
Mohapatra P, Preet R, Choudhuri M, Choudhuri T, Kundu CN. 5-fluorouracil increases the chemopreventive potentials of resveratrol through DNA damage and MAPK signaling pathway in human colorectal cancer cells. Oncol Res. 2011;19:311–21.
Sinha S, Chatterjee S, Paul S, Das B, Dash SR, Das C, et al. Olaparib enhances the resveratrol-mediated apoptosis in breast cancer cells by inhibiting the homologous recombination repair pathway. Exp Cell Res. 2022;420:113338.
Article CAS PubMed Google Scholar
Sinha S, Paul S, Acharya SS, Das C, Dash SR, Bhal S, et al. Combination of resveratrol and PARP inhibitor olaparib efficiently deregulates homologous recombination repair pathway in breast cancer cells through inhibition of TIP60-mediated chromatin relaxation. Med Oncol. 2024;41:49.
Article CAS PubMed Google Scholar
Paul S, Chatterjee S, Sinha S, Dash SR, Pradhan R, Das B, et al. Veliparib (ABT-888), a PARP inhibitor potentiates the cytotoxic activity of 5-fluorouracil by inhibiting MMR pathway through deregulation of MSH6 in colorectal cancer stem cells. Expert Opin Ther Targets. 2023;27:999–1015.
Article CAS PubMed Google Scholar
Satapathy SR, Mohapatra P, Preet R, Das D, Sarkar B, Choudhuri T, et al. Silver-based nanoparticles induce apoptosis in human colon cancer cells mediated through p53. Nanomedicine. 2013;8:1307–22.
Article CAS PubMed Google Scholar
Yu J, Zhang L. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun. 2005;331:851–8.
Article CAS PubMed Google Scholar
Ahmad N, Adhami VM, Afaq F, Feyes DK, Mukhtar H. Resveratrol causes WAF-1/p21-mediated G1-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells. Clin Cancer Res. 2001;7:1466–73.
Baek SY, Hwang UW, Suk HY, Kim YW. Hemistepsin A inhibits cell
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