Erica Acquarone, Elentina K. Argyrousi and Manon van den Berg contributed equally to this work.

Institute for Research on Alzheimer’s Disease and the Aging Brain, 630 West 168th Street, P&S 12- 420D, New York, NY, 10032, USA

Erica Acquarone, Elentina K. Argyrousi, Manon van den Berg, Mauro Fà, Agnieszka Staniszewski, Elisa Calcagno, Elisa Zuccarello, Ottavio Arancio & Jole Fiorito

DiMi Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, 16132, Italy

Erica Acquarone

Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, 6229, Netherlands

Elentina K. Argyrousi & Manon van den Berg

Department of Biomedical and Biotechnological Sciences, Section of Physiology, University of Catania, Catania, 95125, Italy

Walter Gulisano & Daniela Puzzo

Department of Experimental Medicine, Section of General Pathology, School of Medical and Pharmaceutical Sciences, University of Genoa, Genoa, 16132, Italy

Elisa Calcagno

Department of Pharmacology, Physiology and Neuroscience, Rutgers University, Newark, NJ, USA

Luciano D’Adamio

Department of Medicine, Columbia University, New York, NY, 10032, USA

Shi-Xian Deng & Ottavio Arancio

Oasi Research Institute-IRCCS, Troina, 94018, Italy

Daniela Puzzo

Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA

Ottavio Arancio

Department of Life Sciences, New York Institute of Technology, Northern Boulevard, Theobald Science Center, room 425, P.O. Box 8000, Old Westbury, NY, 11568, USA

Jole Fiorito