Abdelrahman AM, Al Salam S, AlMahruqi AS, Al Husseni IS, Mansour MA, Ali BH (2010) N-acetylcysteine improves renal hemodynamics in rats with cisplatin-induced nephrotoxicity. J Appl Toxicol 30:15–21
Article CAS PubMed Google Scholar
Abedini Bajgiran F, Khazaei Koohpar Z, Salehzadeh A (2023) Effects of N-acetylcysteine supplementation on oxidative stress and expression of apoptosis-related genes in testicular tissue of rats exposed to lead. Biol Trace Elem Res 201:2407–2415
Article CAS PubMed Google Scholar
Abusaliya A, Jeong SH, Bhosale PB, Kim HH, Park MY, Kim E, Won CK, Park K, Heo JD, Kim HW, Ahn M, Seong JK, Kim GS (2023) Mechanistic action of cell cycle arrest and intrinsic apoptosis via inhibiting Akt/mTOR and activation of p38-MAPK signaling pathways in Hep3B liver cancer cells by Prunetrin—a flavonoid with therapeutic potential. Nutrients 15:3407
Article CAS PubMed PubMed Central Google Scholar
Ahmadi Kahjoogh H, Yazdanian N, Behrangi E, Roohaninasab M, Hejazi P, Goodarzi A (2022) Efficacy, safety, tolerability, and satisfaction of N-acetylcysteine and pentoxifylline in lichen planopilaris patients under treatment with topical clobetasol: a triple arm blinded randomized controlled trial. Dermatol Ther 35:e15639
Article CAS PubMed Google Scholar
Aiba T, Kono Y, Etoh T, Kawano Y, Oshima Y, Inomata M (2023) Efficacy of cooling therapy and α-lipoic acid derivative against chemotherapy-induced alopecia in an animal model. Cancer Sci 114:1007
Article CAS PubMed Google Scholar
Al-Amarat W, Abukhalil MH, Alruhaimi RS, Alqhtani HA, Aldawood N, Alfwuaires MA, Althunibat OY, Aladaileh SH, Algefare A, Alanezi AA, AbouEl-ezz AM, Ahmeda AF, Mahmoud AM (2022) Upregulation of Nrf2/HO-1 signaling and attenuation of oxidative stress, inflammation, and cell death mediate the protective effect of apigenin against cyclophosphamide hepatotoxicity. Metabolites 12:648
Article CAS PubMed PubMed Central Google Scholar
Althunibat OY, Abukhalil MH, Jghef MM, Alfwuaires MA, Algefare AI, Alsuwayt B, Alazragi R, Abourehab MAS, Almuqati AF, Karimulla S, Aladaileh SH (2023) Hepatoprotective effect of taxifolin on cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in mice: Involvement of Nrf2/HO-1 signaling. Biomol Biomed 23:649–660
CAS PubMed PubMed Central Google Scholar
Andrés-Sánchez N, Fisher D, Krasinska L (2022) Physiological functions and roles in cancer of the proliferation marker Ki-67. J Cell Sci 135:jcs258932
Azhagu Saravana Babu P, Vajiha Aafrin B, Goyali S, Geethika M, Sugumari V, Sukumar M (2023). In: Arunachalam B, Yang X, Sasidharan SP (eds) Bioprospecting of tropical medicinal plants. Springer Nature, Switzerland, pp 611–622
Bancroft JD, Layton C (2019) The hematoxylins and eosin. In: Suvarna SK, Layton C, Bancroft JD (eds) Bancroft’s theory and practice of histological techniques, 8th edn. Elsevier Churchill Livingstone, China, pp 126–138
Böhm M, Bodó E, Funk W, Paus R (2014) α-Melanocyte-stimulating hormone: a protective peptide against chemotherapy-induced hair follicle damage? Br J Dermatol 170:956–960
Chen SS, Zhang Y, Lu QL, Lin Z, Zhao Y (2016) Preventive effects of cedrol against alopecia in cyclophosphamide-treated mice. Environ Toxicol Pharmacol 46:270–276
Article CAS PubMed Google Scholar
Chen H, Zheng H, Li T, Jiang Q, Liu S, Zhou X, Ding Y, Xiang X (2022) Protective effect of oyster peptides derived from Crassostrea gigas on intestinal oxidative damage induced by cyclophosphamide in mice mediated through Nrf2-Keap1 signaling pathway. Front Nutr 9:888960
Article PubMed PubMed Central Google Scholar
Chung MS, Bae WJ, Choi SW, Lee KW, Jeong HC, Bashraheel F, Jeon SH, Jung JW, Yoon B, Kwon EB, Oh HA, Hwang SY, Kim SW (2017) An Asian traditional herbal complex containing Houttuynia cordata Thunb, Perilla frutescens Var. acuta and green tea stimulates hair growth in mice. BMC Complement Altern Med 17:1–11
Cordiano R, Di Gioacchino M, Mangifesta R, Panzera C, Gangemi S, Minciullo PL (2023) Malondialdehyde as a potential oxidative stress marker for allergy-oriented diseases: an update. Molecules 28:5979
Article CAS PubMed PubMed Central Google Scholar
Coşkun Ö, Öztopuz Ö, Büyük B (2021) Possible protective activity of n-acetyl cysteine against cisplatin-induced hepatotoxicity in rats. Mol Biol Rep 48:637–644
Creasy DM, Chapin RE (2018) Male reproductive system. In: Wallig MA, Bolon B, Haschek WM, Rousseaux CG (eds) Fundamentals of toxicologic pathology, 3rd edn. Elsevier-Academic Press, London, pp 459–516
D’Agostini FRANCESCO, Bagnasco MARIA, Giunciuglio DANIELA, Albini ADRIANA, De Flora SILVIO (1998) Inhibition by oral N-acetylcysteine of doxorubicin-induced clastogenicity and alopecia, and prevention of primary tumors and lung micrometastases in mice. Int J Oncol 13:217–241
El Sayed MH, Soltan MY, Sadek A, Hussein Mohamed MAS (2021) Efficacy and tolerability of N-acetyl-cysteine for treatment of the early-onset androgenetic alopecia in men. QJM Int J Med 114:hcab093.024
Enkhtaivan E, Lee CH (2021) Role of amine neurotransmitters and their receptors in skin pigmentation: therapeutic implication. Int J Mol Sci 22:8071
Article CAS PubMed PubMed Central Google Scholar
Fan L, Guan F, Ma Y, Zhang Y, Li L, Sun Y, Cao C, Du H, He M (2022) N-Acetylcysteine improves oocyte quality through modulating the Nrf2 signaling pathway to ameliorate oxidative stress caused by repeated controlled ovarian hyperstimulation. Reprod Fertil Dev 34:736–750
Article CAS PubMed Google Scholar
Haslam IS, Zhou G, Xie G, Teng X, Ao X, Yan Z, Smart E, Rutkowski D, Wierzbicka J, Zhou Y, Huang Z, Zhang Y, Farjo N, Farjo B, Paus R, Yue Z (2021) Inhibition of Shh signaling through MAPK activation controls chemotherapy-induced alopecia. J Invest Dermatol 141:334–344
Article CAS PubMed Google Scholar
Hazra A, Gogtay N (2016) Biostatistics series module 2: overview of hypothesis testing. Indian J Dermatol 61:137–145
Article PubMed PubMed Central Google Scholar
Huang WY, Hong JB, Chang M, Wang SY, Lai SF, Chien HF, Lin SJ (2021) Lower proximal cup and outer root sheath cells regenerate hair bulbs during anagen hair follicle repair after chemotherapeutic injury. Exp Dermatol 30:503–511
Article CAS PubMed Google Scholar
Hussein AM, Ardalan B (1993) Protection against cyclophosphamide-induced alopecia by sulfhydryl-containing agents in the newborn rat animal model. J Eur Acad Dermatol Venereol 2:211–216
Janeczek M, Moy L, Riopelle A, Vetter O, Reserva J, Tung R, Swan J (2019) The potential uses of N-acetylcysteine in dermatology: a review. J Clin Aesthet Dermatol 12:20
PubMed PubMed Central Google Scholar
Jimenez JJ, Huang HS, Yunis AA (1992) Treatment with ImuVert/JV-Acetylcysteine protects rats from cyclophosphamide/cytarabine-induced alopecia. Cancer Investig J 10:271–276
Kim JY, Ohn J, Yoon JS, Kang BM, Park M, Kim S, Lee W, Hwang S, Kim J, Kim KH, Kwon O (2019) Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy. Nat Commun 10:3694
Article PubMed PubMed Central Google Scholar
Kim MH, Kim K, Lee H, Yang WM (2020) Human placenta induces hair regrowth in chemotherapy-induced alopecia via inhibition of apoptotic factors and proliferation of hair follicles. BMC Complement Altern Med Ther 20:1–7
Kim MH, Park SJ, Yang WM (2021) Network pharmacology study and experimental confirmation revealing the ameliorative effects of Decursin on chemotherapy-induced alopecia. J Pharm 14:1150
Kim MJ, Seong KY, Jeong JS, Kim SY, Lee S, Yang SY, An BS (2022) Minoxidil-loaded hyaluronic acid dissolving microneedles to alleviate hair loss in an alopecia animal model. Acta Biomater 143:189–202
Article CAS PubMed Google Scholar
Küçükosmanoğlu İ, Karanis MİE, Ünlü Y, Çöven İ (2022) Evaluation of P57, P53 and Ki67 Expression in Meningiomas. J Korean Neurosurg Soc 65:499–506
Article PubMed PubMed Central Google Scholar
Lu J, Guan S, Luo J, Yuan J, Yan J, Yang C, Tong Q (2023) Levels of oxidative stress in patients with neoadjuvant chemotherapy for gastric cancer: correlation with treatment response. Front Oncol 13:1192192
Article CAS PubMed PubMed Central Google Scholar
Ma Z, Wang W, Pan C, Fan C, Li Y, Wang W, Tian L, Gong F, Zhao C, Zhao Z, Yu S, Yuan M (2022) N-acetylcysteine improves diabetic associated erectile dysfunction in streptozotocin-induced diabetic mice by inhibiting oxidative stress. J Cell Mol Med 26:3527–3537
Article CAS PubMed PubMed Central Google Scholar
Magaki S, Hojat SA, Wei B, So A, Yong WH (2019) An introduction to the performance of immunohistochemistry. In: Clifton NJ (ed) Methods in molecular biology. Humana Press, New York, pp 289–298
Mantawy EM, Said RS, Kassem DH, Abdel-Aziz AK, Badr AM (2020) Novel molecular mechanisms underlying the ameliorative effect of N-acetyl-L-cysteine against ϒ-radiation-induced premature ovarian failure in rats. Ecotoxicol Environ Saf 206:111190
Article CAS PubMed Google Scholar
Mardani N, Mozafarpoor S, Goodarzi A, Nikkhah F (2021) A systematic review of N-acetylcysteine for treatment of acne vulgaris and acne-related associations and consequences: focus on clinical studies. Dermatol Ther 34:e14915
Mlejnek P (2022) Direct interaction between N-acetylcysteine and cytotoxic electrophile—an overlooked in vitro mechanism of protection. Antioxidants 11:1485
留言 (0)