Inability to rescue stalled ribosomes results in overactivation of the integrated stress response
Key Words
ribosome
stalling
protein synthesis
E3 ubiquitin ligase
Hel2
mRNA decay
ribosome quality control
integrated stress response
Gcn2
Gcn4
AbbreviationsMMS
methyl methane sulfonate
RQC
ribosome-quality-control
ISR
integrated stress response
© 2024 THE AUTHORS. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.
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