Nguyen, Christelle, Isabelle Boutron, Gabriel Baron, et al. 2017. Intradiscal glucocorticoid injection for patients with chronic low back pain associated with active discopathy: a randomized trial. Annals of Internal Medicine 166 (547): 556.
Powell, M.C., M. Wilson, P. Szypryt, et al. 1986. Prevalence of lumbar disc degeneration observed by magnetic resonance in symptomless women. Lancet 2: 1366–1367.
Article CAS PubMed Google Scholar
Fritz, Julie M., John S. Magel, Molly McFadden, et al. 2015. Early physical therapy vs usual care in patients with recent-onset low back pain: a randomized clinical trial. JAMA 314: 1459–1467.
Article CAS PubMed Google Scholar
Deyo, Richard A., Michael Von Korff, and David Duhrkoop. 2015. Opioids for low back pain. BMJ 350: g6380.
Article PubMed PubMed Central Google Scholar
Knezevic, Nebojsa Nick, Kenneth D. Candido, Johan WS. Vlaeyen, et al. 2021. Low back pain. Lancet 398: 78–92.
Zhang, Yan, Fan He, Zhi Chen, et al. 2019. Melatonin modulates IL-1β-induced extracellular matrix remodeling in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration and inflammation. Aging (Albany NY) 11: 10499–10512.
Article CAS PubMed Google Scholar
Peng, Baogan, Jianhua Hao, Shuxun Hou, et al. 2006. Possible pathogenesis of painful intervertebral disc degeneration. Spine (Phila Pa 1976) 31: 560–566.
Krock, Emerson, Derek H. Rosenzweig, Anne-Julie. Chabot-Doré, et al. 2014. Painful, degenerating intervertebral discs up-regulate neurite sprouting and CGRP through nociceptive factors. Journal of Cellular and Molecular Medicine 18: 1213–1225.
Article CAS PubMed PubMed Central Google Scholar
Zhao, Kangcheng, Ran An, Qian Xiang, et al. 2021. Acid-sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration. Cell Proliferation 54: e12941.
Article CAS PubMed Google Scholar
Salahi, Armita, Aditya Rane, Li. Xiao, et al. 2022. Single-cell assessment of the modulation of macrophage activation by ex vivo intervertebral discs using impedance cytometry. Biosensors & Bioelectronics 210: 114346.
Li, Xiao-Chuan., Shao-Jian. Luo, Fan Wu, et al. 2022. Macrophage polarization regulates intervertebral disc degeneration by modulating cell proliferation, inflammation mediator secretion, and extracellular matrix metabolism. Frontiers in Immunology 13: 922173.
Article CAS PubMed PubMed Central Google Scholar
Larrañaga, Aitor, Isma Liza Mohd. Isa, Vaibhav Patil, et al. 2018. Antioxidant functionalized polymer capsules to prevent oxidative stress. Acta Biomaterialia 67: 21–31.
Korsunsky, Ilya, Nghia Millard, Jean Fan, et al. 2019. Fast, sensitive and accurate integration of single-cell data with harmony. Nature Methods 16: 1289–1296.
Article CAS PubMed PubMed Central Google Scholar
Butler, Andrew, Paul Hoffman, Peter Smibert, et al. 2018. Integrating single-cell transcriptomic data across different conditions, technologies, and species. Nature Biotechnology 36: 411–420.
Article CAS PubMed PubMed Central Google Scholar
Zhao, Xinlei, Wu. Shuang, Nan Fang, et al. 2020. Evaluation of single-cell classifiers for single-cell RNA sequencing data sets. Briefings in Bioinformatics 21: 1581–1595.
Article CAS PubMed Google Scholar
Yu, G., L.G. Wang, Y. Han, and Q.Y. He. 2012. clusterProfiler: An R package for comparing biological themes among gene clusters. OMICS: A Journal of Integrative Biology 16 (5): 284–287.
Article CAS PubMed Google Scholar
Ionkina, Anastasia A., Gabriela Balderrama-Gutierrez, Krystian J. Ibanez, et al. 2021. Transcriptome analysis of heterogeneity in mouse model of metastatic breast cancer. Breast Cancer Research 23: 93.
Article CAS PubMed PubMed Central Google Scholar
Ai, Liang, Qiang Wang, and Ke. Cheng. 2022. Key genes in the liver fibrosis process are mined based on single-cell transcriptomics. Biochem Biophys Res Communz 598: 131–137.
Jin, Suoqin, Christian F. Guerrero-Juarez, Lihua Zhang, et al. 2021. Inference and analysis of cell-cell communication using Cell Chat. Nature Communications 12: 1088.
Article CAS PubMed PubMed Central Google Scholar
Wu, J., Y. Chen, Z. Liao, et al. 2022. Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration. Molecular Therapy 30 (10): 3241–3256.
Article CAS PubMed PubMed Central Google Scholar
Gan, Yibo, Jian He, Jun Zhu, et al. 2021. Spatially defined single-cell transcriptional profiling characterizes diverse chondrocyte subtypes and nucleus pulposus progenitors in human intervertebral discs. Bone Res 9: 37.
Article CAS PubMed PubMed Central Google Scholar
Zhang, Y., S. Han, M. Kong, et al. 2021. Single-cell RNA-seq analysis identifies unique chondrocyte subsets and reveals involvement of ferroptosis in human intervertebral disc degeneration. Osteoarthritis Cartilage 29: 1324–1334.
Article CAS PubMed Google Scholar
Ji, Tu., Wentian Li, Sidong Yang, et al. 2022. Single-cell transcriptome profiling reveals multicellular ecosystem of nucleus pulposus during degeneration progression. Adv Sci (Weinh) 9: e2103631.
He, Ruijun, Zhe Wang, Min Cui, et al. 2021. HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy. Autophagy 17: 3338–3360.
Article CAS PubMed PubMed Central Google Scholar
Lyu, Feng-Juan., Kenneth M. Cheung, Zhaomin Zheng, et al. 2019. IVD progenitor cells: a new horizon for understanding disc homeostasis and repair. Nature Reviews Rheumatology 15: 102–112.
Díaz-Payno, Pedro J., David C. Browe, Fiona E. Freeman, et al. 2022. In vitro gremlin-1 suppresses hypertrophy of engineered cartilage but not bone formation. Tissue Engineering Part A 28: 724–736.
Lin, Dasheng, Paolo Alberton, Caceres Manuel Delgado, et al. 2020. Loss of tenomodulin expression is a risk factor for age-related intervertebral disc degeneration. Aging Cell 19: e13091.
Article CAS PubMed PubMed Central Google Scholar
Lyu, Feng-Juan., Haowen Cui, Hehai Pan, et al. 2021. Painful intervertebral disc degeneration and inflammation: from laboratory evidence to clinical interventions. Bone Res 9: 7.
Article CAS PubMed PubMed Central Google Scholar
Risbud, Makarand V., and Irving M. Shapiro. 2014. Role of cytokines in intervertebral disc degeneration: pain and disc content. Nature Reviews Rheumatology 10: 44–56.
Article CAS PubMed Google Scholar
Gorth, Deborah J., Irving M. Shapiro, and Makarand V. Risbud. 2018. Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration. Cell Death & Disease 10: 7.
Yang, Sidong, Feng Zhang, Jiangtao Ma, et al. 2020. Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen. Ageing Research Reviews 57: 100978.
Article CAS PubMed Google Scholar
Bian, Jiang, Feng Cai, Hao Chen, et al. 2021. Modulation of local overactive inflammation via injectable hydrogel microspheres. Nano Letters 21: 2690–2698.
Article CAS PubMed Google Scholar
Marfia, G., S.E. Navone, C. Di Vito, et al. 2015. Gene expression profile analysis of human mesenchymal stem cells from herniated and degenerated intervertebral discs reveals different expression of osteopontin. Stem Cells Development 24: 320–328.
Article CAS PubMed Google Scholar
Ma, Lichun, Limin Wang, Subreen A. Khatib, et al. 2021. Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Journal of Hepatology 75: 1397–1408.
Article CAS PubMed PubMed Central Google Scholar
Wang, Chao, Lili Yang, Xu. Shaoheng, et al. 2022. Systematic analysis of the role and significance of target genes of active ingredients of traditional Chinese medicine injections in the progression and immune microenvironment of hepatocellular carcinoma. Frontiers in Pharmacology 13: 1095965.
Article CAS PubMed Google Scholar
Li, Yang, Zuolong Chen, Qiong Wang, et al. 2022. Identification of hub proteins in cerebrospinal fluid as potential biomarkers of Alzheimer’s disease by integrated bioinformatics. Journal of Neurology 270 (3): 1487–1500.
de Luna, Noemí, Álvaro. Carbayo, Oriol Dols-Icardo, et al. 2023. Neuroinflammation-
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