Proctor EK, Geng E. A new lane for science. Science. 2021;374(6568):659. https://doi.org/10.1126/science.abn0184.

Article  CAS  PubMed  Google Scholar 

Kerkhoff AD, Farrand E, Marquez C, Cattamanchi A, Handley MA. Addressing health disparities through implementation science—a need to integrate an equity lens from the outset. Implement Sci. 2022;17. https://doi.org/10.1186/s13012-022-01189-5.

Baumann AA, Long PD. Equity in implementation science is long overdue. Stanford Social Innovation Review; 2021. Available from: https://ssir.org/articles/entry/equity_in_implementation_science_is_long_overdue. Cited 2023 Nov 14.

Brownson RC, Kumanyika SK, Kreuter MW, Haire-Joshu D. Implementation science should give higher priority to health equity. Implement Sci. 2021;16. https://doi.org/10.1186/s13012-021-01097-0.

Moise N, Cené CW, Tabak RG, Young DR, Mills KT, Essien UR, et al. Leveraging implementation science for cardiovascular health equity: a scientific statement from the American Heart Association. Circulation. 2022;146(19):e260–78. https://doi.org/10.1161/CIR.0000000000001096.

Article  PubMed  Google Scholar 

Bangash H, Kullo IJ. Implementation science to increase adoption of genomic medicine: an urgent need. J Pers Med. 2020;11(1). https://doi.org/10.3390/jpm11010019.

Amrock SM, Duell BP, Knickelbine T, Martin SS, O’Brien EC, Watson KE, et al. Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FH™ patient registry. Atherosclerosis. 2017;267:19–26. https://doi.org/10.1016/j.atherosclerosis.2017.10.006.

Article  CAS  PubMed  Google Scholar 

Okunrintemi V, Valero-Elizondo J, Patrick B, Salami J, Tibuakuu M, Ahmad S, et al. Gender differences in patient-reported outcomes among adults with atherosclerotic cardiovascular disease. J Am Heart Assoc. 2018;7(24):e010498. https://doi.org/10.1161/JAHA.118.010498.

Article  PubMed  PubMed Central  Google Scholar 

Curran GM, Landes SJ, McBain SA, Pyne JM, Smith JD, Fernandez ME, et al. Reflections on 10 years of effectiveness-implementation hybrid studies. Front Health Serv. 2022;2. https://doi.org/10.3389/frhs.2022.1053496.

Palinkas LA, Aarons GA, Horwitz S, Chamberlain P, Hurlburt M, Landsverk J. Mixed method designs in implementation research. Adm Policy Ment Health. 2011;38(1):44–53. https://doi.org/10.1007/s10488-010-0314-z.

Article  PubMed  Google Scholar 

Creswell JW, Klassen AC, Clark VLP, Smith KC. Best practices for mixed methods research in the health sciences. National Institutes of Health Office of Behavioral and Social Sciences; 2011. Available from: https://obssr.od.nih.gov/sites/obssr/files/Best_Practices_for_Mixed_Methods_Research.pdf. Cited 2024 Jan 11.

Pellecchia M, Mandell DS, Nuske HJ, Azad G, Wolk CB, Maddox B, et al. Community-academic partnerships in implementation research. J Commun Psychol. 2018;46(7):941–52. https://doi.org/10.1002/jcop.21981.

Article  Google Scholar 

Pellecchia M, Arnold KT, Tomczuk L, Beidas RS. Engaging stakeholders. In: Weiner BJ, Sherr K, Lewis CC, editors. Practical implementation science. Springer; 2022. p. 133–54.

Google Scholar 

Ramanadhan S, Davis MM, Armstrong R, Baquero B, Ko LK, Leng JC, et al. Participatory implementation science to increase the impact of evidence-based cancer prevention and control. Cancer Causes Control. 2018;29(3):363–9. https://doi.org/10.1007/s10552-018-1008-1.

Article  PubMed  PubMed Central  Google Scholar 

Damschroder LJ, Reardon CM, Widerquist MAO, Lowery J. The updated consolidated framework for implementation research based on user feedback. Implement Sci. 2022;17. https://doi.org/10.1186/s13012-022-01245-0.

Volpp KG, Loewenstein G, Asch DA. Behavioral economics and health. In: Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J, editors. Harrison's principles of internal medicine. 20th ed. McGraw-Hill; 2018.

Kahneman D, Knetsch JL, Thaler RH. Anomalies: the endowment effect, loss aversion, and status quo bias. J Econ Perspect. 1991;5(1):193–206. https://doi.org/10.1257/jep.5.1.193.

Article  Google Scholar 

Kahneman D, Tversky A. Prospect theory: an analysis of decision under risk. In: MacLean LC, Ziemba WT, editors. Handbook of the fundamentals of financial decision making: part II. World Scientific Publishing; 2013. p. 99–127.

Chapter  Google Scholar 

Volpp KG, Troxel AB, Pauly MV, Glick HA, Puig A, Asch DA, et al. A randomized, controlled trial of financial incentives for smoking cessation. N Engl J Med. 2009;360(7):699–709. https://doi.org/10.1056/NEJMsa0806819.

Article  CAS  PubMed  Google Scholar 

Patel MS, Day SC, Halpern SD, Hanson CW, Martinez JR, Honeywell S, et al. Generic medication prescription rates after health system–wide redesign of default options within the electronic health record. JAMA Intern Med. 2016;176(6):847–8. https://doi.org/10.1001/jamainternmed.2016.1691.

Article  PubMed  PubMed Central  Google Scholar 

Doshi JA, Lim R, Li P, Young PP, Lawnicki VF, State JJ, et al. A synchronized prescription refill program improved medication adherence. Health Aff (Millwood). 2016;35(8):1504–12. https://doi.org/10.1377/hlthaff.2015.1456.

Article  PubMed  Google Scholar 

Last BS, Buttenheim AM, Timon CE, Mitra N, Beidas RS. Systematic review of clinician-directed nudges in healthcare contexts. BMJ Open. 2021;11(7):e048801. https://doi.org/10.1136/bmjopen-2021-048801.

Article  PubMed  PubMed Central  Google Scholar 

Jenssen BP, Schnoll R, Beidas RS, Bekelman J, Bauer A-M, Evers-Casey S, et al. Cluster randomized pragmatic clinical trial testing behavioral economic implementation strategies to improve tobacco treatment for patients with cancer who smoke. J Clin Oncol. 2023;41(28):4511–21. https://doi.org/10.1200/JCO.23.00355.

Beidas R, Linn K, Johnson C, Maye M, Quintana L, Wright L, et al. Primary outcomes from an effectiveness-implementation trial of strategies to implement a secure firearm storage program as a universal suicide prevention strategy in pediatric primary care. Paper presented at: IASR/AFSP International Summit on Suicide Research; 2023; Barcelona.

Shelton RC, Chambers DA, Glasgow RE. An extension of RE-AIM to enhance sustainability: addressing dynamic context and promoting health equity over time. Front Public Health. 2020;8. https://doi.org/10.3389/fpubh.2020.00134.

Woodward EN, Matthieu MM, Uchendu US, Rogal S, Kirchner JE. The health equity implementation framework: proposal and preliminary study of hepatitis C virus treatment. Implement Sci. 2019;14. https://doi.org/10.1186/s13012-019-0861-y.

Gidding SS, Champagne MA, de Ferranti SD, Defesche J, Ito MK, Knowles JW, et al. The agenda for familial hypercholesterolemia: a scientific statement from the American Heart Association. Circulation. 2015;132(22):2167–92. https://doi.org/10.1161/cir.0000000000000297.

Article  PubMed  Google Scholar 

McGowan MP, Hosseini Dehkordi SH, Moriarty PM, Duell PB. Diagnosis and treatment of heterozygous familial hypercholesterolemia. J Am Heart Assoc. 2019;8(24):e013225. https://doi.org/10.1161/JAHA.119.013225.

Article  PubMed  PubMed Central  Google Scholar 

Goldberg AC, Hopkins PN, Toth PP, Ballantyne CM, Rader DJ, Robinson JG, et al. Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on familial hypercholesterolemia. J Clin Lipidol. 2011;5(3):133–40. https://doi.org/10.1016/j.jacl.2011.04.003.

Article  PubMed  Google Scholar 

Kusters DM, Wiegman A, Kastelein JJ, Hutten BA. Carotid intima-media thickness in children with familial hypercholesterolemia. Circ Res. 2014;114(2):307–10. https://doi.org/10.1161/circresaha.114.301430.

Article  CAS  PubMed  Google Scholar 

More Detailed Information on Key Tier 1 Applications – Familial Hypercholesterolemia. Centers for Disease Control and Prevention; 2014. Available from: https://www.cdc.gov/genomics/implementation/toolkit/fh_1.htm. Cited 2023 Nov 15.

Cascade Testing: Finding Family Members with Genetic Conditions. Centers for Disease Control and Prevention; 2022. Available from: https://www.cdc.gov/genomics/disease/cascade_testing/cascade_finding.htm. Cited 2023 Nov 10.

Louter L, Defesche J, Roeters van Lennep J. Cascade screening for familial hypercholesterolemia: practical consequences. Atheroscler Suppl. 2017;30:77–85. https://doi.org/10.1016/j.atherosclerosissup.2017.05.019.

Article  PubMed  Google Scholar 

Wierzbicki AS, Humphries SE, Minhas R. Familial hypercholesterolaemia: summary of NICE guidance. BMJ. 2008;337:a1095. https://doi.org/10.1136/bmj.a1095.

Article  PubMed  Google Scholar 

Genest J, Hegele RA, Bergeron J, Brophy J, Carpentier A, Couture P, et al. Canadian Cardiovascular Society position statement on familial hypercholesterolemia. Can J Cardiol. 2014;30(12):1471–81. https://doi.org/10.1016/j.cjca.2014.09.028.

Article  PubMed  Google Scholar 

Lee C, Rivera-Valerio M, Bangash H, Prokop L, Kullo IJ. New case detection by cascade testing in familial hypercholesterolemia: a systematic review of the literature. Circ Genom Precis Med. 2019;12(11):e002723. https://doi.org/10.1161/circgen.119.002723.

Article  PubMed  PubMed Central  Google Scholar 

Zuurbier LC, Defesche JC, Wiegman A. Successful genetic screening and creating awareness of familial hypercholesterolemia and other heritable dyslipidemias in the Netherlands. Genes. 2021;12(8):1168. https://doi.org/10.3390/genes12081168.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Umans-Eckenhausen MA, Defesche JC, Sijbrands EJ, Scheerder RL, Kastelein JJ. Review of first 5 years of screening for familial hypercholesterolaemia in the Netherlands. Lancet. 2001;357(9251):165–8. https://doi.org/10.1016/S0140-6736(00)03587-X.

Article  CAS  PubMed  Google Scholar 

Campbell-Salome G, Jones LK, Masnick MF, Walton NA, Ahmed CD, Buchanan AH, et al. Developing and optimizing innovative tools to address familial hypercholesterolemia underdiagnosis: identification methods, patient activation, and cascade testing for familial hypercholesterolemia. Circ Genom Precis Med. 2021;14(1):e003120. https://doi.org/10.1161/CIRCGEN.120.003120.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miller AA, Bangash H, Smith CY, Wood-Wentz CM, Bailey KR, Kullo IJ. A pragmatic clinical trial of cascade testing for familial hypercholesterolemia. Genet Med. 2022;24(12):2535–43. https://doi.org/10.1016/j.gim.2022.08.026.

Article  CAS  PubMed  PubMed Central  Google Scholar 

McGowan MP, Cuchel M, Ahmed CD, Khera A, Weintraub WS, Wilemon KA, et al. A proof-of-concept study of cascade screening for familial hypercholesterolemia in the US, adapted from the Dutch model. Am J Prev Cardiol. 2021;6:100170. https://doi.org/10.1016/j.ajpc.2021.100170.

Article  PubMed  PubMed Central  Google Scholar 

Ajufo E, DeGoma EM, Raper A, Yu KD, Cuchel M, Rader DJ. A randomized controlled trial of genetic testing and cascade screening in familial hypercholesterolemia. Genet Med. 2021;23(9):1697–704. https://doi.org/10.1038/s41436-021-01192-z.

Article  CAS  PubMed  Google Scholar 

Sarkies M, Jones LK, Pang J, Sullivan D, Watts GF. How can implementation science improve the care of familial hypercholesterolaemia? Curr Atheroscler Rep. 2023;25(4):133–43. https://doi.org/10.1007/s11883-023-01090-6.

Article  PubMed  PubMed Central  Google Scholar 

Sarkies MN, Testa L, Best S, Moullin JC, Sullivan D, Bishop W, et al. Barriers to and facilitators of implementing guidelines for detecting familial hypercholesterolaemia in Australia. Heart Lung Circ. 2023;32(11):1347–53. https://doi.org/10.1016/j.hlc.2023.09.012.

Article  PubMed