Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Cancer J Clin. 2018;68:394–424. https://doi.org/10.3322/caac.21492.

Article  Google Scholar 

Weidenbaum C, Gibson MK. Approach to localized squamous cell Cancer of the Esophagus. Curr Treat Options Oncol. 2022;23:1370–87. https://doi.org/10.1007/s11864-022-01003-w.

Article  PubMed  PubMed Central  Google Scholar 

Waters JK, Reznik SI. Update on management of squamous cell esophageal Cancer. Curr Oncol Rep. 2022;24:375–85. https://doi.org/10.1007/s11912-021-01153-4.

Article  CAS  PubMed  Google Scholar 

Liu X, Wu L, Zhang D, Lin P, Long H, Zhang L, Ma G. Prognostic impact of lymph node metastasis along the left gastric artery in esophageal squamous cell carcinoma. J Cardiothorac Surg. 2021;16:124. https://doi.org/10.1186/s13019-021-01466-2.

Article  PubMed  PubMed Central  Google Scholar 

Morgan E, Soerjomataram I, Rumgay H, Coleman HG, Thrift AP, Vignat J, Laversanne M, Ferlay J, Arnold M. The Global Landscape of esophageal squamous cell carcinoma and esophageal adenocarcinoma incidence and mortality in 2020 and projections to 2040: new estimates from GLOBOCAN 2020. Gastroenterology. 2022;163. https://doi.org/10.1053/j.gastro.2022.05.054.

Amin MB, Greene FL, Edge SB, Compton CC, Gershenwald JE, Brookland RK, Meyer L, Gress DM, Byrd DR, Winchester DP. The Eighth Edition AJCC Cancer staging Manual: continuing to build a bridge from a population-based to a more personalized approach to cancer staging. Cancer J Clin. 2017;67:93–9. https://doi.org/10.3322/caac.21388.

Article  Google Scholar 

Huang W, Wu L, Liu X, Long H, Rong T, Ma G. Preoperative serum C-reactive protein levels and postoperative survival in patients with esophageal squamous cell carcinoma: a propensity score matching analysis. J Cardiothorac Surg. 2019;14:167. https://doi.org/10.1186/s13019-019-0981-0.

Article  PubMed  PubMed Central  Google Scholar 

Wu LL, Wang JL, Huang W, Liu X, Huang YY, Zeng J, Cui CY, Lu JB, Lin P, Long H, et al. Prognostic modeling of patients undergoing surgery alone for esophageal squamous cell carcinoma: a histopathological and computed tomography based quantitative analysis. Front Oncol. 2021;11:565755. https://doi.org/10.3389/fonc.2021.565755.

Article  PubMed  PubMed Central  Google Scholar 

Wu LL, Ma QL, Huang W, Liu X, Qiu LH, Lin P, Long H, Zhang LJ, Ma GW. A prognostic model for stratification of stage IB/IIA esophageal squamous cell carcinoma: a retrospective study. BMC Gastroenterol. 2021;21:59. https://doi.org/10.1186/s12876-021-01636-5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rice TW, Ishwaran H, Blackstone EH, Hofstetter WL, Kelsen DP, Apperson-Hansen C. Recommendations for clinical staging (cTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals. Dis Esophagus: Official J Int Soc Dis Esophagus. 2016;29:913–9. https://doi.org/10.1111/dote.12540.

Article  Google Scholar 

Nair M, Sandhu SS, Sharma AK. Cancer molecular markers: a guide to cancer detection and management. Sem Cancer Biol. 2018;52:39–55. https://doi.org/10.1016/j.semcancer.2018.02.002.

Article  CAS  Google Scholar 

Yang HL, Dong YB, Elliott MJ, Liu TJ, McMasters KM. Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells. Clin Cancer Research: Official J Am Association Cancer Res. 2000;6:1579–89.

CAS  Google Scholar 

Lin Q-H, Que F-C, Gu C-P, Zhong D-S, Zhou D, Kong Y, Yu L, Liu S-W. ABT-263 induces G1/G0-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro. Acta Pharmacol Sin. 2017;38:1632–41. https://doi.org/10.1038/aps.2017.78.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiao Q-H, Wang Y, Zhang A-N, Liu Q-Q, Zhou Q-B. PSMA7 promotes the malignant proliferation of esophageal cancer. Heliyon. 2024;10:e23173. https://doi.org/10.1016/j.heliyon.2023.e23173.

Article  CAS  PubMed  Google Scholar 

Ueno H, Hirai T, Nishimoto N, Hihara J, Inoue H, Yoshida K, Yamashita Y, Toge T, Tsubota N. Prediction of lymph node metastasis by p53, p21(Waf1), and PCNA expression in esophageal cancer patients. J Exp Clin Cancer Res. 2003;22:239–45.

CAS  PubMed  Google Scholar 

Du L, Fei Z, Song S, Wei N. Antitumor activity of Lobaplatin against esophageal squamous cell carcinoma through caspase-dependent apoptosis and increasing the Bax/Bcl-2 ratio. Biomed Pharmacother. 2017;95:447–52. https://doi.org/10.1016/j.biopha.2017.08.119.

Article  CAS  PubMed  Google Scholar 

Dong Wang L, Bin Yue W, Zhou Y, Wei Feng C, Liu B, Zhou Q, Ying Jia Y, Zheng S, Gao SS, Ji Xie X, et al. Endoscopic screening and determination of p53 and proliferating cell nuclear antigen in esophageal multistage carcinogenesis: a comparative study between high- and low-risk populations in Henan, northern China. Dis Esophagus: Official J Int Soc Dis Esophagus. 2002;15:80–4.

Article  CAS  Google Scholar 

Bahl R, Arora S, Nath N, Mathur M, Shukla NK, Ralhan R. Novel polymorphism in p21(waf1/cip1) cyclin dependent kinase inhibitor gene: association with human esophageal cancer. Oncogene. 2000;19:323–8.

Article  CAS  PubMed  Google Scholar 

Sun C-X, Zhu F, Qi L. Demethylated miR-216a regulates high mobility Group Box 3 promoting growth of Esophageal Cancer cells through Wnt/β-Catenin pathway. Front Oncol. 2021;11:622073. https://doi.org/10.3389/fonc.2021.622073.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ma J, Zhang Y, Deng H, Liu Y, Lei X, He P, Dong W. Thymoquinone inhibits the proliferation and invasion of esophageal cancer cells by disrupting the AKT/GSK-3β/Wnt signaling pathway via PTEN upregulation. Phytother Res. 2020;34:3388–99. https://doi.org/10.1002/ptr.6795.

Article  CAS  PubMed  Google Scholar 

Juchniewicz A, Kowalczuk O, Milewski R, Laudański W, Dzięgielewski P, Kozłowski M, Nikliński J. MMP-10, MMP-7, TIMP-1 and TIMP-2 mRNA expression in esophageal cancer. Acta Biochim Pol. 2017;64:295–9. https://doi.org/10.18388/abp.2016_1408.

Article  CAS  PubMed  Google Scholar 

Huang C, Xu S, Luo Z, Li D, Wang R, Wang T. Epidemiological evidence between variants in Matrix Metalloproteinases-2, -7, and – 9 and Cancer Risk. Front Oncol. 2022;12:856831. https://doi.org/10.3389/fonc.2022.856831.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang J, Wu M, Zheng D, Zhang H, Lv Y, Zhang L, Tan H-S, Zhou H, Lao Y-Z, Xu H-X. Garcinol inhibits esophageal cancer metastasis by suppressing the p300 and TGF-β1 signaling pathways. Acta Pharmacol Sin. 2020;41:82–92. https://doi.org/10.1038/s41401-019-0271-3.

Article  CAS  PubMed  Google Scholar 

Zou S, Yang J, Guo J, Su Y, He C, Wu J, Yu L, Ding W-Q, Zhou J. RAD18 promotes the migration and invasion of esophageal squamous cell cancer via the JNK-MMPs pathway. Cancer Lett. 2018;417:65–74. https://doi.org/10.1016/j.canlet.2017.12.034.

Article  CAS  PubMed  Google Scholar 

Duan H, Ding X, Luo H. KISS-1, mediated by promoter methylation, suppresses esophageal squamous cell Carcinoma Metastasis via MMP2/9/MAPK Axis. Dig Dis Sci. 2022;67:4780–96. https://doi.org/10.1007/s10620-021-07335-1.

Article  CAS  PubMed  Google Scholar 

Li Y, Ma J, Guo Q, Duan F, Tang Fa, Zheng P, Zhao Z, Lu G. Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma. Dis Esophagus: Official J Int Soc Dis Esophagus. 2009;22:664–7. https://doi.org/10.1111/j.1442-2050.2008.00928.x.

Article  Google Scholar 

Peng Y, Wang Y, Tang N, Sun D, Lan Y, Yu Z, Zhao X, Feng L, Zhang B, Jin L, et al. Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway. J Exp Clin Cancer Res. 2018;37:248. https://doi.org/10.1186/s13046-018-0926-9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li C, Wu J, Zhang L, Wang F, Xu L, Zhao Y, Xiao Y, Zhuang F, Hou L, Zhao D, et al. Brief report: Acetaminophen reduces Neoadjuvant Chemoimmunotherapy Efficacy in patients with NSCLC by promoting Neutrophil Extracellular trap formation: analysis from a phase 2 clinical trial. JTO Clin Res Rep. 2023;4:100556. https://doi.org/10.1016/j.jtocrr.2023.100556.

Article  PubMed  PubMed Central  Google Scholar 

Wen J, Xuan B, Gao Y, Liu Y, Wang L, He L, Meng X, Zhou T, Tao Y, Guo K, et al. Lnc-17Rik promotes the immunosuppressive function of myeloid-derived suppressive cells in esophageal cancer. Cell Immunol. 2023;385:104676. https://doi.org/10.1016/j.cellimm.2023.104676.

Article  CAS  PubMed  Google Scholar 

Zhu P, Yu H, Zhou K, Bai Y, Qi R, Zhang S. 3,3’-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway. J Exp Clin Cancer Res. 2020;39:113. https://doi.org/10.1186/s13046-020-01618-7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang W, Li Y, Li R, Chen W, Song M, Zhang Q, Chen S. The Prognostic significance of FOXD1 expression in Head and Neck squamous cell carcinoma. J Personalized Med. 2023;13. https://doi.org/10.3390/jpm13030530.

Liu Ye, Chen Y, Wang F, Lin J, Tan X, Chen C, Wu L-L, Zhang X, Wang Y, Shi Y, et al. Caveolin-1 promotes glioma progression and maintains its mitochondrial inhibition resistance. Discov Oncol. 2023;14:161. https://doi.org/10.1007/s12672-023-00765-5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang Q, Wu L, Xu M, Yan D, Shao J, Yan S. Osalmid, a Novel identified RRM2 inhibitor, enhances Radiosensitivity of Esophageal Cancer. Int J Radiat Oncol Biol Phys. 2020;108:1368–79. https://doi.org/10.1016/j.ijrobp.2020.07.2322.

Article  PubMed  Google Scholar 

Wu L-L, Lin W-K, Qian J-Y, Ma S-S, Li M-J, Li K, Li Z-X, Lan G, Xie D. Prognostic assessment of lung adenocarcinoma patients with early-staging diseases: a nomogram based on coagulation-related factors. Eur J Cardiothorac Surg. 2023;ezad313.