Validation of new biometry instruments against the gold standard and establishing repeatability are important before being utilized for clinical and research applications.

This study aimed to investigate intersession repeatability of the MYAH optical biometer and corneal topographer and examine agreement with the Lenstar LS900 optical biometer in healthy young adults.

Forty participants (mean age, 25.2 ± 3.1 years) presented for two visits, 2 to 4 days apart. At each visit, measurements for right eyes were collected with the MYAH and Lenstar LS 900 and included axial length, corneal power, white-to-white distance, and pupil diameter. Bland-Altman analysis was used to assess the intrasession agreement between the MYAH and Lenstar for each parameter and intersession repeatability for the two devices. For each device, coefficient of variation and intraclass correlation coefficient were calculated, and paired t tests between visits were performed to assess intersession repeatability.

Good agreement (mean difference [95% limits of agreement]) between the MYAH and Lenstar was found for axial length (−0.01 [−0.07 to 0.04] mm), corneal power (−0.02 D [−0.15 to 0.19 d]), white-to-white distance (−0.13 [−0.43 to 0.17] mm), and pupil diameter (−0.27 [−0.79 to 1.33] mm). The limits of agreement, coefficient of variations, and intraclass correlation coefficients for MYAH-measured parameters were −0.04 to 0.04, 0.06%, and >0.99 for axial length; −0.24 to 0.19, 0.18%, and >0.99 for corneal power; −1.05 to 1.15, 0.57%, and 0.96 for white-to-white distance; and −0.17 to 0.21, 7.0%, and 0.76 for pupil diameter, with no significant difference between visits (p>0.05 for all), indicating good intersession repeatability. Similar intersession repeatability was also noted for Lenstar.

Findings show good intersession repeatability of the MYAH and good agreement with the Lenstar for axial length, corneal power, and white-to-white distance in young adults. Pupil diameter was more variable, likely due to the dynamic nature of the pupil. This study provides validation and supports the use of the MYAH for ocular biometry.