Ran HH, Zhang R, Lu XC, Yang B, Fan H, Zhu HL (2012) Imatinib-induced decompensated heart failure in an elderly patient with chronic myeloid leukemia: case report and literature review. Journal of geriatric cardiology: JGC 9(4):411–414
PubMed PubMed Central Google Scholar
Franceschino A, Tornaghi L, Benemacher V, Assouline S, Gambacorti-Passerini C (2008) Alterations in creatine kinase, phosphate and lipid values in patients with chronic myeloid leukemia during treatment with imatinib. Haematologica 93(2):317–318
Gordon JK, Magid SK, Maki RG, Fleisher M, Berman E (2010) Elevations of creatine kinase in patients treated with imatinib mesylate (Gleevec). Leuk Res 34(6):827–829
Article CAS PubMed Google Scholar
Kekäle M, Peltoniemi M, Airaksinen M (2015) Patient-reported adverse drug reactions and their influence on adherence and quality of life of chronic myeloid leukemia patients on per oral tyrosine kinase inhibitor treatment. Patient Prefer Adherence 9:1733–1740
Article PubMed PubMed Central Google Scholar
Adenis A, Bouché O, Bertucci F, Kalbacher E, Fournier C, Cassier P et al (2012) Serum creatine kinase increase in patients treated with tyrosine kinase inhibitors for solid tumors. Medical oncology (Northwood, London, England) 29(4):3003–3008
Article CAS PubMed Google Scholar
Penel N, Blay JY, Adenis A (2008) Imatinib as a possible cause of severe rhabdomyolysis. N Engl J Med 358(25):2746–2747
Article CAS PubMed Google Scholar
Kerkelä R, Grazette L, Yacobi R, Iliescu C, Patten R, Beahm C et al (2006) Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 12(8):908–916
Gambacorti-Passerini C, Tornaghi L, Franceschino A, Piazza R, Corneo G, Pogliani E (2007) In reply to ‘Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.’ Nature med 13(1):13–14. author reply 5–6
Hatfield A, Owen S, Pilot PR (2007) In reply to ‘Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.’ Nature med 13(1):13. author reply 5–6
Article CAS PubMed Google Scholar
Saad SY, Alkharfy KM, Arafah MM (2006) Cardiotoxic effects of arsenic trioxide/imatinib mesilate combination in rats. J Pharm Pharmacol 58(4):567–573
Article CAS PubMed Google Scholar
Dong B, Chen DF, Bu XH, Qin HB, Xi Y (2020) Effect of imatinib on DOCA-induced myocardial fibrosis in rats through P38 MAPK signaling pathway. Eur Rev Med Pharmacol Sci 24(4):2028–2036
Al-Ali HK, Krahl R, Orth M, Perlowski S, Otto S, Deininger MW et al (2004) Persistently increased creatine kinase levels in patients with chronic myeloid leukemia treated with imatinib correlate with major cytogenetic remission. Blood 104(11):2933
Peng B, Lloyd P, Schran H (2005) Clinical pharmacokinetics of imatinib. Clin Pharmacokinet 44(9):879–894
Article CAS PubMed Google Scholar
Eechoute K, Sparreboom A, Burger H, Franke RM, Schiavon G, Verweij J et al (2011) Drug transporters and imatinib treatment: implications for clinical practice. Clinical cancer research: an official journal of the American Association for Cancer Research 17(3):406–415
Article CAS PubMed Google Scholar
Mlejnek P, Dolezel P, Faber E, Kosztyu P (2011) Interactions of N-desmethyl imatinib, an active metabolite of imatinib, with P-glycoprotein in human leukemia cells. Ann Hematol 90(7):837–842
Article CAS PubMed Google Scholar
Filppula AM, Laitila J, Neuvonen PJ, Backman JT (2012) Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates. Br J Pharmacol 165(8):2787–2798
Article CAS PubMed PubMed Central Google Scholar
von Mehren M, Widmer N (2011) Correlations between imatinib pharmacokinetics, pharmacodynamics, adherence, and clinical response in advanced metastatic gastrointestinal stromal tumor (GIST): an emerging role for drug blood level testing? Cancer Treat Rev 37(4):291–299
Larson RA, Druker BJ, Guilhot F, O’Brien SG, Riviere GJ, Krahnke T et al (2008) Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study. Blood 111(8):4022–4028
Article CAS PubMed Google Scholar
Picard S, Titier K, Etienne G, Teilhet E, Ducint D, Bernard MA et al (2007) Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia. Blood 109(8):3496–3499
Article CAS PubMed Google Scholar
Bankar A, Lipton JH (2022) Association of creatine kinase elevation with clinical outcomes in chronic myeloid leukemia: a retrospective cohort study. Leuk Lymphoma 63(1):179–188
Article CAS PubMed Google Scholar
Nasser A, Hussein A, Chamba C, Yonazi M, Mushi R, Schuh A et al (2021) Molecular response to imatinib in patients with chronic myeloid leukemia in Tanzania. Blood Adv 5(5):1403–1411
Article CAS PubMed PubMed Central Google Scholar
Jabbour E, Jones D, Kantarjian HM, O’Brien S, Tam C, Koller C et al (2009) Long-term outcome of patients with chronic myeloid leukemia treated with second-generation tyrosine kinase inhibitors after imatinib failure is predicted by the in vitro sensitivity of BCR-ABL kinase domain mutations. Blood 114(10):2037–2043
Article CAS PubMed PubMed Central Google Scholar
Pfirrmann M, Baccarani M, Saussele S, Guilhot J, Cervantes F, Ossenkoppele G et al (2016) Prognosis of long-term survival considering disease-specific death in patients with chronic myeloid leukemia. Leukemia 30(1):48–56
Article CAS PubMed Google Scholar
Sokal JE, Cox EB, Baccarani M, Tura S, Gomez GA, Robertson JE et al (1984) Prognostic discrimination in “good-risk” chronic granulocytic leukemia. Blood 63(4):789–799
Article CAS PubMed Google Scholar
Hasford J, Pfirrmann M, Hehlmann R, Allan NC, Baccarani M, Kluin-Nelemans JC et al (1998) A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon alfa. Writing Committee for the Collaborative CML Prognostic Factors Project Group. Journal of the National Cancer Institute 90(11):850–8
Article CAS PubMed Google Scholar
Hewitt J, Rusnak D, Cox-Kennett N, Larratt L, Turner R (2007) HyperCKemia in CML patients on imatinib mesylate. Blood 110:2965
Baccarani M, Deininger MW, Rosti G, Hochhaus A, Soverini S, Apperley JF et al (2013) European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood 122(6):872–884
Article CAS PubMed PubMed Central Google Scholar
Omran MM, Abdelfattah R, Moussa HS, Alieldin N, Shouman SA (2020) Association of the trough, peak/trough ratio of imatinib, pyridine-N-oxide imatinib and ABCG2 SNPs 34 G>A and SLCO1B3 334 T>G with imatinib response in Egyptian chronic myeloid leukemia patients. Front Oncol 10:1348
Article PubMed PubMed Central Google Scholar
Titier K, Picard S, Ducint D, Teilhet E, Moore N, Berthaud P et al (2005) Quantification of imatinib in human plasma by high-performance liquid chromatography-tandem mass spectrometry. Ther Drug Monit 27(5):634–640
Article CAS PubMed Google Scholar
Shimazaki C, Ochiai N, Uchida R, Fuchida SI, Okano A, Ashihara E et al (2003) Intramuscular edema as a complication of treatment with imatinib. Leukemia 17(4):804–805
Article CAS PubMed Google Scholar
Cohen MH, Williams G, Johnson JR, Duan J, Gobburu J, Rahman A et al (2002) Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. Clinical cancer research: an official journal of the American Association for Cancer Research 8(5):935–942
Berman E, Nicolaides M, Maki RG, Fleisher M, Chanel S, Scheu K et al (2006) Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med 354(19):2006–2013
Article CAS PubMed Google Scholar
Betsholtz C (2003) Biology of platelet-derived growth factors in development. Birth Defects Res C Embryo Today 69(4):272–285
Article CAS PubMed Google Scholar
Zhao Y, Haginoya K, Sun G, Dai H, Onuma A, Iinuma K (2003) Platelet-derived growth factor and its receptors are related to the progression of human muscular dystrophy: an immunohistochemical study. J Pathol 201(1):149–159
Article CAS PubMed Google Scholar
Baird MF, Graham SM, Baker JS, Bickerstaff GF (2012) Creatine-kinase- and exercise-related muscle damage implications for muscle performance and recovery. Journal of nutrition and metabolism 2012:960363
Article PubMed PubMed Central Google Scholar
Oosthuyse T, Bosch AN (2017) The effect of gender and menstrual phase on serum creatine kinase activity and muscle soreness following downhill running. Antioxidants (Basel, Switzerland). 6(1)
Cook JC, Wong E, Haywood LJ (1990) Creatine kinase: race-gender differences in patients hospitalized for suspected myocardial infarction. J Natl Med Assoc 82(4):249–254
留言 (0)