Deubiquitinase BRCC3 promotes the migration, invasion and EMT progression of colon adenocarcinoma by stabilizing MET expression

Barata-Antunes C, Alves R, Talaia G, Casal M, Geros H, Mans R, Paiva S (2021) Endocytosis of nutrient transporters in fungi: the ART of connecting signaling and trafficking. Comput Struct Biotechnol J 19:1713–1737

Article  PubMed  PubMed Central  Google Scholar 

Boromand N, Hasanzadeh M, ShahidSales S, Farazestanian M, Gharib M, Fiuji H, Behboodi N, Ghobadi N, Hassanian SM, Ferns GA et al (2018) Clinical and prognostic value of the C-Met/HGF signaling pathway in cervical cancer. J Cell Physiol 233:4490–4496

Article  PubMed  Google Scholar 

Bryan S, Masoud H, Weir HK, Woods R, Lockwood G, Smith L, Brierley J, Gospodarowicz M, Badets N (2018) Cancer in Canada: stage at diagnosis. Health Rep 29:21–25

PubMed  Google Scholar 

Chebouti I, Kasimir-Bauer S, Buderath P, Wimberger P, Hauch S, Kimmig R, Kuhlmann JD (2017) EMT-like circulating tumor cells in ovarian cancer patients are enriched by platinum-based chemotherapy. Oncotarget 8:48820–48831

Article  PubMed  PubMed Central  Google Scholar 

Cooper EM, Boeke JD, Cohen RE (2010) Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin. J Biol Chem 285:10344–10352

Article  PubMed  Google Scholar 

Czyz M (2018) HGF/c-MET signaling in melanocytes and Melanoma. Int J Mol Sci 19

Dongre A, Weinberg RA (2019) New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer. Nat Rev Mol Cell Biol 20:69–84

Article  PubMed  Google Scholar 

Du F, Li X, Feng W, Qiao C, Chen J, Jiang M, Qiu Z, Qian M, Tian D, Nie Y et al (2020) SOX13 promotes colorectal cancer metastasis by transactivating SNAI2 and c-MET. Oncogene 39:3522–3540

Article  PubMed  Google Scholar 

Fabregas JC, Ramnaraign B, George TJ (2022) Clinical updates for Colon Cancer Care in 2022. Clin Colorectal Cancer 21:198–203

Article  PubMed  Google Scholar 

Fu J, Su X, Li Z, Deng L, Liu X, Feng X, Peng J (2021) HGF/c-MET pathway in cancer: from molecular characterization to clinical evidence. Oncogene 40:4625–4651

Article  PubMed  Google Scholar 

Gu YY, Yang M, Zhao M, Luo Q, Yang L, Peng H, Wang J, Huang SK, Zheng ZX, Yuan XH et al (2015) The de-ubiquitinase UCHL1 promotes gastric cancer metastasis via the akt and Erk1/2 pathways. Tumour Biol 36:8379–8387

Article  PubMed  Google Scholar 

Harper JW, Elledge SJ (2007) The DNA damage response: ten years after. Mol Cell 28:739–745

Article  PubMed  Google Scholar 

Hu Y, Zhang Y, Ding M, Xu R (2021) Long noncoding RNA TMPO-AS1/miR-126-5p/BRCC3 axis accelerates gastric cancer progression and angiogenesis via activating PI3K/Akt/mTOR pathway. J Gastroenterol Hepatol 36:1877–1888

Article  PubMed  Google Scholar 

Huang D, Nagata Y, Grossmann V, Radivoyevitch T, Okuno Y, Nagae G, Hosono N, Schnittger S, Sanada M, Przychodzen B et al (2015) BRCC3 mutations in myeloid neoplasms. Haematologica 100:1051–1057

PubMed  PubMed Central  Google Scholar 

Kallergi G, Markomanolaki H, Giannoukaraki V, Papadaki MA, Strati A, Lianidou ES, Georgoulias V, Mavroudis D, Agelaki S (2009) Hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients. Breast Cancer Res 11:R84

Article  PubMed  PubMed Central  Google Scholar 

Kim HJ (2022) Therapeutic strategies for ovarian Cancer in point of HGF/c-MET targeting. Med (Kaunas) 58

Lawal B, Wang YC, Wu ATH, Huang HS (2021) Pro-oncogenic c-Met/EGFR, Biomarker signatures of the Tumor Microenvironment are clinical and Therapy Response prognosticators in Colorectal Cancer, and therapeutic targets of 3-Phenyl-2H-benzo[e][1,3]-Oxazine-2,4(3H)-Dione derivatives. Front Pharmacol 12:691234

Article  PubMed  PubMed Central  Google Scholar 

Liew SK, Azmi MN, In L, Awang K, Nagoor NH (2017) Anti-proliferative, apoptotic induction, and anti-migration effects of hemi-synthetic 1’S-1’-acetoxychavicol acetate analogs on MDA-MB-231 breast cancer cells. Drug Des Devel Ther 11:2763–2776

Article  PubMed  PubMed Central  Google Scholar 

Lu W, Kang Y (2019) Epithelial-mesenchymal plasticity in Cancer Progression and Metastasis. Dev Cell 49:361–374

Article  PubMed  PubMed Central  Google Scholar 

Lv S, Wang X, Bai X, Ning H, Li Y, Wen H, Lu W, Wang J (2020) Mesenchymal epithelial transition factor regulates tumor necrosis factor-related apoptotic induction ligand resistance in hepatocellular carcinoma cells through down-regulation of cyclin B1. Int J Biochem Cell Biol 128:105844

Article  PubMed  Google Scholar 

Malik R, Mambetsariev I, Fricke J, Chawla N, Nam A, Pharaon R, Salgia R (2020) MET receptor in oncology: from biomarker to therapeutic target. Adv Cancer Res 147:259–301

Article  PubMed  Google Scholar 

Meyer T, Jahn N, Lindner S, Rohner L, Dolnik A, Weber D, Scheffold A, Kopff S, Paschka P, Gaidzik VI et al (2020) Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1). Leukemia 34:404–415

Article  PubMed  Google Scholar 

Miller KD, Nogueira L, Devasia T, Mariotto AB, Yabroff KR, Jemal A, Kramer J, Siegel RL (2022) Cancer treatment and survivorship statistics, 2022. CA Cancer J Clin 72:409–436

Article  PubMed  Google Scholar 

Ning Y, Zhang W, Hanna DL, Yang D, Okazaki S, Berger MD, Miyamoto Y, Suenaga M, Schirripa M, El-Khoueiry A et al (2018) Clinical relevance of EMT and stem-like gene expression in circulating tumor cells of metastatic colorectal cancer patients. Pharmacogenomics J 18:29–34

Article  PubMed  Google Scholar 

Niu T, De Rosny C, Chautard S, Rey A, Patoli D, Groslambert M, Cosson C, Lagrange B, Zhang Z, Visvikis O et al (2021) NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly. Nat Commun 12:5862

Article  PubMed  PubMed Central  Google Scholar 

Okamoto K, Bartocci C, Ouzounov I, Diedrich JK, Yates JR 3rd, Denchi EL (2013) A two-step mechanism for TRF2-mediated chromosome-end protection. Nature 494:502–505

Article  PubMed  PubMed Central  Google Scholar 

Paemka L, Mahajan VB, Ehaideb SN, Skeie JM, Tan MC, Wu S, Cox AJ, Sowers LP, Gecz J, Jolly L et al (2015) Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinase. PLoS Genet 11:e1005022

Article  PubMed  PubMed Central  Google Scholar 

Pan J, Qiao Y, Chen C, Zang H, Zhang X, Qi F, Chang C, Yang F, Sun M, Lin S et al (2021) USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1. Cell Death Dis 12:1051

Article  PubMed  PubMed Central  Google Scholar 

Pastushenko I, Blanpain C (2019) EMT Transition States during Tumor Progression and Metastasis. Trends Cell Biol 29:212–226

Article  PubMed  Google Scholar 

Pothula SP, Xu Z, Goldstein D, Pirola RC, Wilson JS, Apte MV (2020) Targeting HGF/c-MET Axis in Pancreatic Cancer. Int J Mol Sci 21

Py BF, Kim MS, Vakifahmetoglu-Norberg H, Yuan J (2013) Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol Cell 49:331–338

Article  PubMed  Google Scholar 

Raj S, Kesari KK, Kumar A, Rathi B, Sharma A, Gupta PK, Jha SK, Jha NK, Slama P, Roychoudhury S et al (2022) Molecular mechanism(s) of regulation(s) of c-MET/HGF signaling in head and neck cancer. Mol Cancer 21:31

Article  PubMed  PubMed Central  Google Scholar 

Rokavec M, Horst D, Hermeking H (2017) Cellular Model of Colon cancer progression reveals signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis. Cancer Res 77:1854–1867

Article  PubMed  Google Scholar 

Siegel RL, Miller KD, Goding Sauer A, Fedewa SA, Butterly LF, Anderson JC, Cercek A, Smith RA, Jemal A (2020) Colorectal cancer statistics, 2020. CA Cancer J Clin 70:145–164

Article  PubMed  Google Scholar 

Song L, Zhang L, Zhou Y, Shao X, Xu Y, Pei D, Wang Q (2022) ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma. Cell Death Discov 8:219

Article  PubMed  PubMed Central  Google Scholar 

Sun ZZ, Zhang T, Ning K, Zhu R, Liu F, Tang SC, Jiang B, Hua D (2016) B7-H3 upregulates BRCC3 expression, antagonizing DNA damage caused by 5-Fu. Oncol Rep 36:231–238

Article  PubMed  Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F (2021) Global Cancer statistics 2020: GLOBOCAN estimates of incidence and Mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71:209–249

Article  PubMed  Google Scholar 

Sylvester PW (2014) Targeting met mediated epithelial-mesenchymal transition in the treatment of breast cancer. Clin Transl Med 3:30

Article  PubMed  PubMed Central  Google Scholar 

Tao H, Liao Y, Yan Y, He Z, Zhou J, Wang X, Peng J, Li S, Liu T (2021) BRCC3 promotes tumorigenesis of bladder Cancer by activating the NF-kappaB signaling pathway through targeting TRAF2. Front Cell Dev Biol 9:720349

Article  PubMed  PubMed Central  Google Scholar 

Vogel JD, Felder SI, Bhama AR, Hawkins AT, Langenfeld SJ, Shaffer VO, Thorsen AJ, Weiser MR, Chang GJ, Lightner AL et al (2022) The American Society of Colon and rectal surgeons Clinical Practice guidelines for the management of Colon cancer. Dis Colon Rectum 65:148–177

Article  PubMed  Google Scholar 

Wang S, Qiu J, Liu L, Su C, Qi L, Huang C, Chen X, Zhang Y, Ye Y, Ding Y et al (2020) CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET. J Exp Clin Cancer Res 39:168

Article  PubMed  PubMed Central 

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