Goga M, Elecko J, Marcincinova M, Rucova D, Backorova M, Backor M Lichen Metabolites: An Overview of Some Secondary Metabolites and Their Biological Potential. In: Merillon, JM, Ramawat, K (eds) Co-Evolution of Secondary Metabolites. Reference Series in Phytochemistry. Springer, Cham. 2018. https://doi.org/10.1007/978-3-319-76887-8_57-1

Zhao Y, Wang M, Xu B. A comprehensive review on secondary metabolites and health-promoting effects of edible lichen. J Funct Foods. 2021;80:104283 https://doi.org/10.1016/j.jff.2020.104283

Article  CAS  Google Scholar 

Ureña-Vacas I, González-Burgos E, Divakar PK, Gómez-Serranillos MPJ. Lichen depsides and tridepsides: progress in pharmacological approaches. J Fungi 2023;9:116 https://doi.org/10.3390/jof9010116

Article  CAS  Google Scholar 

Karagoz ID, Ozaslan M, Kilic IH, Guler I, Uyar C, Tuter D, et al. Hepatoprotective effect of diffractaic acid on carbon tetrachloride-induced liver damage in rats. Biotechnol Biotechnol Equip. 2015;29:1011–6. https://doi.org/10.1080/13102818.2015.1056754

Article  CAS  Google Scholar 

Honda NK, Pavan FR, Coelho RG, Andrade Leite SR, Micheletti AC, Lopes TIB, et al. Antimycobacterial activity of lichen substances. Phytomedicine. 2010;17:328–32. https://doi.org/10.1016/j.phymed.2009.07.018

Article  CAS  PubMed  Google Scholar 

Bayir Y, Odabasoglu F, Cakir A, Aslan A, Suleyman H, Halici M, et al. The inhibition of gastric mucosal lesion, oxidative stress and neutrophil-infiltration in rats by the lichen constituent diffractaic acid. Phytomedicine. 2006;13:584–90. https://doi.org/10.1016/j.phymed.2005.07.002

Article  CAS  PubMed  Google Scholar 

Sachin MB, Mahalakshmi SN, Kekuda TRP. Insecticidal efficacy of lichens and their metabolites - A mini review. J Appl Pharm Sci. 2018;8:159–64. https://doi.org/10.7324/JAPS.2018.81020

Article  CAS  Google Scholar 

Yamamoto Y, Miura Y, Kinoshita Y, Higuchi M, Yamada Y, Murakami A, et al. Screening of tissue cultures and thalli of lichens and some of their active constituents for inhibition of tumor-promoter-induced Epstein-Barr virus activation. Chem Pharm Bull. 1995;43:1388–90. https://doi.org/10.1248/cpb.43.1388

Article  CAS  Google Scholar 

Loeanurit N, Tuong TL, Nguyen V-K, Vibulakhaophan V, Hengphasatporn K, Shigeta Y, et al. Lichen-derived diffractaic acid inhibited dengue virus replication in a cell-based system. Molecules. 2023;28:974 https://doi.org/10.3390/molecules28030974

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2095–128. https://doi.org/10.1016/S0140-6736(12)61728-0

Article  PubMed  PubMed Central  Google Scholar 

Shi T, McAllister DA, O’Brien KL, Simoes EAF, Madhi SA, Gessner BD, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. Lancet. 2017;390:946–58. https://doi.org/10.1016/S0140-6736(17)30938-8

Article  PubMed  PubMed Central  Google Scholar 

Falsey AR, Hennessey PA, Formica MA, Cox C, Walsh EE. Respiratory syncytial virus infection in elderly and high-risk adults. N Engl J Med. 2005;352:1749–59. https://doi.org/10.1056/NEJMoa043951

Article  CAS  PubMed  Google Scholar 

Rezaee F, Linfield DT, Harford TJ, Piedimonte G. Ongoing developments in RSV prophylaxis: a clinician’s analysis. Curr Opin Virol. 2017;24:70–78. https://doi.org/10.1016/j.coviro.2017.03.015

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heylen E, Neyts J, Jochmans D. Drug candidates and model systems in respiratory syncytial virus antiviral drug discovery. Biochem Pharm. 2017;127:1–12. https://doi.org/10.1016/j.bcp.2016.09.014

Article  CAS  PubMed  Google Scholar 

Elawar F, Oraby AK, Kieser Q, Jensen LD, Culp T, West FG, et al. Pharmacological targets and emerging treatments for respiratory syncytial virus bronchiolitis. Pharm Ther. 2021;220:107712 https://doi.org/10.1016/j.pharmthera.2020.107712

Article  CAS  Google Scholar 

Lai D, Odimegwu DC, Esimone C, Grunwald T, Proksch P. Phenolic Compounds with In Vitro Activity against Respiratory Syncytial Virus from the Nigerian Lichen Ramalina farinacea. Planta Med. 2013;79:1440–6. https://doi.org/10.1055/s-0033-1350711

Article  CAS  PubMed  Google Scholar 

Baram GI, Grachev MA, Komarova NI, Perelroyzen MP, Bolvanov YA, Kuzmin SV, et al. Micro-column liquid chromatography with multi-wave-length photometric detection: I. The OB-4 micro-column liquid chromatograph. J Chromatogr A 1983;264:69–90. https://doi.org/10.1016/S0021-9673(01)95007-1

Article  CAS  Google Scholar 

Köhler G, Milstein C. Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion. Eur J Immunol. 1976;6:511–9. https://doi.org/10.1002/eji.1830060713

Article  PubMed  Google Scholar