Slotkin JR, Cahill KS, Tharin SA, Shapiro EM (2007) Cellular magnetic resonance imaging: nanometer and micrometer size particles for noninvasive cell localization. Neurotherapeutics 4(3):428–433

Article  PubMed  PubMed Central  Google Scholar 

Shapiro EM, Sharer K, Skrtic S, Koretsky AP (2006) In vivo detection of single cells by MRI. Magn Reson Med 55(2):242–249

Article  PubMed  Google Scholar 

Shapiro EM, Skrtic S, Sharer K, Hill JM, Dunbar CE, Koretsky AP (2004) MRI detection of single particles for cellular imaging. Proc Natl Acad Sci USA 101(30):10901–10906

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Cheng H-LM (2023) A primer on in vivo cell tracking using MRI. Front Med 10:1193459

Article  Google Scholar 

Ahrens ET, Bulte JW (2013) Tracking immune cells in vivo using magnetic resonance imaging. Nat Rev Immunol 13(10):755–763

Article  CAS  PubMed  Google Scholar 

Kelly JJ, Saee-Marand M, Nyström NN, Evans MM, Chen Y, Martinez FM, Hamilton AM, Ronald JA (2021) Safe harbor-targeted CRISPR-Cas9 homology-independent targeted integration for multimodality reporter gene-based cell tracking. Sci Adv 7:eabc3791

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Nyström NN, McRae SW, Martinez FM, Kelly JJ, Scholl TJ, Ronald JA (2023) A Genetically Encoded Magnetic Resonance Imaging Reporter Enables Sensitive Detection and Tracking of Spontaneous Metastases in Deep Tissues. Cancer Res 83(5):673–685

Article  PubMed  Google Scholar 

Nystrom NN, Hamilton AM, Xia W, Liu S, Scholl TJ, Ronald JA (2019) Longitudinal Visualization of Viable Cancer Cell Intratumoral Distribution in Mouse Models Using Oatp1a1-Enhanced Magnetic Resonance Imaging. Invest Radiol 54(5):302–311

Article  PubMed  Google Scholar 

Wu MR, Hsiao JK, Liu HM, Huang YY, Tseng YJ, Chou PT, Weng TI, Yang CY (2019) In vivo imaging of insulin-secreting human pancreatic ductal cells using MRI reporter gene technique: A feasibility study. Magn Reson Med 82(2):763–774

Article  CAS  PubMed  Google Scholar 

Wu MR, Liu HM, Lu CW, Shen WH, Lin IJ, Liao LW, Huang YY, Shieh MJ, Hsiao JK (2018) Organic anion-transporting polypeptide 1B3 as a dual reporter gene for fluorescence and magnetic resonance imaging. FASEB J 32(3):1705–1715

Article  CAS  PubMed  Google Scholar 

Patrick PS, Hammersley J, Loizou L, Kettunen MI, Rodrigues TB, Hu DE, Tee SS, Hesketh R, Lyons SK, Soloviev D, Lewis DY, Aime S, Fulton SM, Brindle KM (2014) Dual-modality gene reporter for in vivo imaging. Proc Natl Acad Sci USA 111(1):415–420

Article  ADS  CAS  PubMed  Google Scholar 

Wang T, Chen Y, Nystrom NN, Liu S, Fu Y, Martinez FM, Scholl TJ, Ronald JA (2023) Visualizing cell-cell communication using synthetic notch activated MRI. Proc Natl Acad Sci USA 120(11):e2216901120

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hagenbuch B, Stieger B (2013) The SLCO (former SLC21) superfamily of transporters. Mol Aspects Med 34(2–3):396–412

Article  CAS  PubMed  PubMed Central  Google Scholar 

Leonhardt M, Keiser M, Oswald S, Kuhn J, Jia J, Grube M, Kroemer HK, Siegmund W, Weitschies W (2010) Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters. Drug Metab Dispos 38(7):1024–1028

Article  PubMed  Google Scholar 

Planchamp C, Gex-Fabry M, Dornier C, Quadri R, Reist M, Ivancevic MK, Vallee JP, Pochon S, Terrier F, Balant L, Stieger B, Meier PJ, Pastor CM (2004) Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor. Invest Radiol 39(8):506–515

Article  CAS  PubMed  Google Scholar 

Vilgrain V, Van Beers BE, Pastor CM (2016) Insights into the diagnosis of hepatocellular carcinomas with hepatobiliary MRI. J Hepatol 64(3):708–716

Article  PubMed  Google Scholar 

Planchamp C, Hadengue A, Stieger B, Bourquin J, Vonlaufen A, Frossard JL, Quadri R, Becker CD, Pastor CM (2007) Function of both sinusoidal and canalicular transporters controls the concentration of organic anions within hepatocytes. Mol Pharmacol 71(4):1089–1097

Article  CAS  PubMed  Google Scholar 

Shuboni-Mulligan DD, Parys M, Blanco-Fernandez B, Mallett CL, Schnegelberger R, Takada M, Chakravarty S, Hagenbuch B, Shapiro EM (2019) Dynamic Contrast-Enhanced MRI of OATP Dysfunction in Diabetes. Diabetes 68(2):271–280

Article  CAS  PubMed  Google Scholar 

Mir FF, Tomaszewski RP, Shuboni-Mulligan DD, Mallett CL, Hix JML, Ether ND, Shapiro EM (2019) Chimeric mouse model for MRI contrast agent evaluation. Magn Reson Med 82(1):387–394

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kiryu S, Inoue Y, Watanabe M, Izawa K, Shimada M, Tojo A, Yoshikawa K, Ohtomo K (2009) Evaluation of gadoxetate disodium as a contrast agent for mouse liver imaging: comparison with gadobenate dimeglumine. Magn Reson Imaging 27(1):101–107

Article  CAS  PubMed  Google Scholar 

Runge VM, Wells JW, Williams NM (1996) Hepatic abscesses. Magnetic resonance imaging findings using gadolinium-BOPTA. Invest Radiol 31(12):781–8

Article  CAS  PubMed  Google Scholar 

Borusewicz P, Stańczyk E, Kubiak K, Spużak J, Glińska-Suchocka K, Jankowski M, Sławuta P, Kubiak-Nowak D, Podgórski P (2019) Magnetic resonance imaging of liver tumors using gadoxetic acid (Gd-EOB-DTPA) - pilot study. BMC Vet Res 15(1):293

Article  PubMed  PubMed Central  Google Scholar 

Benness G, Khangure M, Morris I, Warwick A, Burrows P, Vogler H (1994) Kinetics and magnetic resonance imaging of Gd-EOB-DTPA in dogs. Invest Radiol 29(Suppl 2):S177–S178

Article  PubMed  Google Scholar 

Marks AL, Hecht S, Stokes JE, Conklin GA, Deanna KH (2014) Effects of gadoxetate disodium (Eovist((R))) contrast on magnetic resonance imaging characteristics of the liver in clinically healthy dogs. Vet Radiol Ultrasound 55(3):286–291

Article  PubMed  Google Scholar 

Hix JML, Mallett CL, Latourette M, Munoz KA, Shapiro EM (2020) Dynamic contrast enhanced MRI with clinical hepatospecific MRI contrast agents in pigs: initial experience. bioRxiv 2020.02.18.946541

Bashor CJ, Hilton IB, Bandukwala H, Smith DM, Veiseh O (2022) Engineering the next generation of cell-based therapeutics. Nat Rev Drug Discovery 21(9):655–675

Article  CAS  PubMed  Google Scholar 

de Vries IJ, Lesterhuis WJ, Barentsz JO, Verdijk P, van Krieken JH, Boerman OC, Oyen WJ, Bonenkamp JJ, Boezeman JB, Adema GJ, Bulte JW, Scheenen TW, Punt CJ, Heerschap A, Figdor CG (2005) Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 23(11):1407–1413

Article  PubMed  Google Scholar 

Mallett CL, Shuboni-Mulligan DD, Shapiro EM (2018) Tracking Neural Progenitor Cell Migration in the Rodent Brain Using Magnetic Resonance Imaging. Front Neurosci 12:995

Article  PubMed  Google Scholar 

Shapiro EM, Skrtic S, Koretsky AP (2005) Sizing it up: cellular MRI using micron-sized iron oxide particles. Magn Reson Med 53(2):329–338

Article  PubMed  Google Scholar 

Aherne E, Chow K, Carr J (2020) Cardiac T(1) mapping: Techniques and applications. J Magnet Resonance Imaging : JMRI 51(5):1336–1356

Article  PubMed  Google Scholar 

Bernau K, Lewis CM, Petelinsek AM, Reagan MS, Niles DJ, Mattis VB, Meyerand ME, Suzuki M, Svendsen CN (2016) In Vivo Tracking of Human Neural Progenitor Cells in the Rat Brain Using Magnetic Resonance Imaging Is Not Enhanced by Ferritin Expression. Cell Transplant 25(3):575–592

Article  PubMed  Google Scholar 

Ziemian S, Green C, Sourbron S, Jost G, Schütz G, Hines CDG (2021) Ex vivo gadoxetate relaxivities in rat liver tissue and blood at five magnetic field strengths from 1.41 to 7 T.  NMR Biomed 34:e4401

Article  CAS  PubMed  Google Scholar 

de Graaf W, Hausler S, Heger M, van Ginhoven TM, van Cappellen G, Bennink RJ, Kullak-Ublick GA, Hesselmann R, van Gulik TM, Stieger B (2011) Transporters involved in the hepatic uptake of (99m)Tc-mebrofenin and indocyanine green. J Hepatol 54(4):738–745

Article  PubMed  Google Scholar 

Hernández Lozano I, Langer O (2020) Use of imaging to assess the activity of hepatic transporters. Expert Opin Drug Metab Toxicol 16(2):149–164

Article  PubMed  PubMed Central  Google Scholar