GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021;20(10):795–820.

Article  Google Scholar 

Owolabi MO, Thrift AG, Mahal A, et al. Primary stroke prevention worldwide: translating evidence into action. Lancet Public Health. 2022;7(1):e74-85.

Article  PubMed  Google Scholar 

Johnson CO, Nguyen M, Roth GA, et al. Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019;18(5):439–58.

Article  Google Scholar 

Lindsay MP, Norrving B, Sacco RL, et al. World Stroke Organization (WSO): Global Stroke Fact Sheet 2019. Int J Stroke. 2019;14(8):806–17.

Article  PubMed  Google Scholar 

Feigin VL, Brainin M, Norrving B, et al. World Stroke Organization (WSO): Global Stroke Fact Sheet 2022. Int J Stroke. 2022;17(1):18–29.

Article  PubMed  Google Scholar 

GBD 2016 Stroke Collaborators. Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019;18(5):439–58.

Article  Google Scholar 

Ak C, Gupta R, Warkade V. Study of clinical profile and risk factors for ischemic stroke in young adults. J Assoc Phys India. 2022;70(4):11–2.

Google Scholar 

Rodríguez-Campello A, Jiménez-Conde J, Ois Á, et al. Dietary habits in patients with ischemic stroke: a case-control study. PLoS ONE. 2014;9(12):e114716.

Article  ADS  PubMed  PubMed Central  Google Scholar 

Lavados PM, Mazzon E, Rojo A, Brunser AM, Olavarría VV. Pre-stroke adherence to a Mediterranean diet pattern is associated with lower acute ischemic stroke severity: a cross-sectional analysis of a prospective hospital-register study. BMC Neurol. 2020;20(1):252.

Article  PubMed  PubMed Central  Google Scholar 

Tang H, Gong F, Guo H, et al. Malnutrition and risk of mortality in ischemic stroke patients treated with intravenous thrombolysis. Front Aging Neurosci. 2022;14:834973. 

Article  PubMed  PubMed Central  Google Scholar 

Bouziana SD, Tziomalos K. Malnutrition in patients with acute stroke. J Nutr Metab. 2011;2011:167898.

Article  PubMed  PubMed Central  Google Scholar 

Yoo S-H, Kim JS, Kwon SU, Yun S-C, Koh J-Y, Kang D-W. Undernutrition as a predictor of poor clinical outcomes in acute ischemic stroke patients. Arch Neurol. 2008;65(1):39–43.

Article  PubMed  Google Scholar 

Horn JW, Feng T, Mørkedal B, et al. Obesity and risk for first ischemic stroke depends on metabolic syndrome: the HUNT study. Stroke. 2021;52(11):3555–61.

Article  PubMed  Google Scholar 

Shiozawa M, Kaneko H, Itoh H, et al. Association of body mass index with ischemic and hemorrhagic stroke. Nutrients. 2021;13(7):2343.

Article  PubMed  PubMed Central  Google Scholar 

Bardugo A, Fishman B, Libruder C, et al. Body mass index in 1.9 million adolescents and stroke in young adulthood. Stroke. 2021;52(6):2043–52.

Article  PubMed  Google Scholar 

Golubnitschaja O, Potuznik P, Polivka J, et al. Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach. EPMA J. 2022;13(4):535–45.

Article  PubMed  PubMed Central  Google Scholar 

Golubnitschaja O, Liskova A, Koklesova L, et al. Caution, “normal” BMI: health risks associated with potentially masked individual underweight-EPMA Position Paper 2021. EPMA J. 2021;12(3):243–64.

Article  PubMed  PubMed Central  Google Scholar 

Song DK, Hong YS, Sung Y-A, Lee H. Body mass index and stroke risk among patients with diabetes mellitus in Korea. PLoS ONE. 2022;17(9):e0275393.

Article  PubMed  PubMed Central  Google Scholar 

Chaudhary D, Khan A, Gupta M, et al. Obesity and mortality after the first ischemic stroke: Is obesity paradox real? PLoS ONE. 2021;16(2):e0246877.

Article  PubMed  PubMed Central  Google Scholar 

Oesch L, Tatlisumak T, Arnold M, Sarikaya H. Obesity paradox in stroke – myth or reality? A systematic review. PLoS ONE. 2017;12(3):e0171334.

Article  PubMed  PubMed Central  Google Scholar 

Ho L-C, Wang H-K, Chiu L-T, et al. Protein energy wasting–based nutritional assessment predicts outcomes of acute ischemic stroke and solves the epidemiologic paradox. Nutrition. 2022;93:111431.

Article  PubMed  Google Scholar 

Middleton LE, Corbett D, Brooks D, et al. Physical activity in the prevention of ischemic stroke and improvement of outcomes: a narrative review. Neurosci Biobehav Rev. 2013;37(2):133–7.

Article  PubMed  Google Scholar 

Cowan LT, Tome J, Mallhi AK, et al. Changes in physical activity and risk of ischemic stroke: the ARIC study. Int J Stroke. 2023;18(2):173–9.

Article  PubMed  Google Scholar 

Guo S, Huang Y, Zhang Y, Huang H, Hong S, Liu T. Impacts of exercise interventions on different diseases and organ functions in mice. J Sport Health Sci. 2020;9(1):53–73.

Article  PubMed  Google Scholar 

Krako Jakovljevic N, Pavlovic K, Jotic A, et al. Targeting mitochondria in diabetes. IJMS. 2021;22(12):6642.

Article  PubMed  PubMed Central  Google Scholar 

Lee Y, Min K, Talbert EE, et al. Exercise protects cardiac mitochondria against ischemia-reperfusion injury. Med Sci Sports Exerc. 2012;44(3):397–405.

Article  PubMed  Google Scholar 

Di Meo S, Venditti P. Mitochondria in exercise-induced oxidative stress. Biol Signals Recept. 2001;10(1–2):125–40.

Article  PubMed  Google Scholar 

Layec G, Blain GM, Rossman MJ, et al. Acute high-intensity exercise impairs skeletal muscle respiratory capacity. Med Sci Sports Exerc. 2018;50(12):2409–17.

Article  PubMed  PubMed Central  Google Scholar 

Avellaneda-Gómez C, Vivanco-Hidalgo RM, Olmos S, et al. Air pollution and surrounding greenness in relation to ischemic stroke: a population-based cohort study. Environ Int. 2022;161:107147.

Article  PubMed  Google Scholar 

Dev P, Gupta P, Mahapatra A, et al. Systematic review and meta-analysis of environmental toxic metal contaminants and the risk of ischemic stroke. Ann Indian Acad Neurol. 2022;25(6):1159–66.

Article  PubMed  PubMed Central  Google Scholar 

Lee HR, Yoo JE, Choi H, et al. Tuberculosis and risk of ischemic stroke: a nationwide cohort study. Stroke. 2022;53(11):3401–9.

Article  PubMed  Google Scholar 

Wei Y, Tang S, Xie Z, et al. Pulmonary tuberculosis-related ischemic stroke: a retrospective case control study. J Inflamm Res. 2022;15:4239–49.

Article  PubMed  PubMed Central  Google Scholar 

Li J, Lee DH, Hu J, et al. Dietary inflammatory potential and risk of cardiovascular disease among men and women in the U.S. J Am Coll Cardiol. 2020;76(19):2181–93.

Article  PubMed  PubMed Central  Google Scholar 

Golubnitschaja O, Baban B, Boniolo G, et al. Medicine in the early twenty-first century: paradigm and anticipation - EPMA position paper 2016. EPMA J. 2016;7(1):23.

Article  PubMed  PubMed Central  Google Scholar 

Leary MC, Saver JL. Annual incidence of first silent stroke in the United States: a preliminary estimate. Cerebrovasc Dis. 2003;16(3):280–5.

Article  PubMed  Google Scholar 

Vermeer SE, Longstreth WT, Koudstaal PJ. Silent brain infarcts: a systematic review. Lancet Neurol. 2007;6(7):611–9.

Article  PubMed  Google Scholar 

Kobayashi S, Okada K, Koide H, Bokura H, Yamaguchi S. Subcortical silent brain infarction as a risk factor for clinical stroke. Stroke. 1997;28(10):1932–9.

Article  PubMed  Google Scholar 

Uehara T, Tabuchi M, Mori E. Risk factors for silent cerebral infarcts in subcortical white matter and basal ganglia. Stroke. 1999;30(2):378–82.

Article  PubMed  Google Scholar 

Lee S-C, Park S-J, Ki H-K, et al. Prevalence and risk factors of silent cerebral infarction in apparently normal adults. Hypertension. 2000;36(1):73–7.

Article  PubMed  Google Scholar 

Matsui T, Arai H, Yuzuriha T, et al. Elevated plasma homocysteine levels and risk of silent brain infarction in elderly people. Stroke. 2001;32(5):1116–9.

Article  PubMed  Google Scholar 

Maeshima S, Moriwaki H, Ozaki F, Okita R, Yamaga H, Ueyoshi A. Silent cerebral infarction and cognitive function in middle-aged neurologically healthy subjects. Acta Neurol Scand. 2002;105(3):179–84.

Article  PubMed