Enhanced Oral Bioavailability of Isoformononetin Through Nanoemulsion: Development, Optimization, and Characterization

Tchoumtchoua J, Mouchili OR, Ateba SB, Zingue S, Halabalaki M, Mbanya JC, et al. Safety assessment of the methanol extract of the stem bark of Amphimas pterocarpoides Harms: acute and subchronic oral toxicity studies in Wistar rats. Toxicol Rep. Elsevier. 2014;1:877–84.

CAS  Google Scholar 

Prokudina EA, Havlíček L, Al-Maharik N, Lapčík O, Strnad M, Gruz J. Rapid UPLC–ESI–MS/MS method for the analysis of isoflavonoids and other phenylpropanoids. J Food Compost Anal. Academic Press. 2012;26:36–42.

Article  CAS  Google Scholar 

Lapčı́k O, Hill M, Černý I, Lachman J, Al-Maharik N, Adlercreutz H, Hampl R. Immunoanalysis of isoflavonoids in Pisum sativum and Vigna radiata. Plant Sci. 1999 Oct 29;148(2):111–9.

Bhargavan B, Gautam AK, Singh D, Kumar A, Chaurasia S, Tyagi AM, et al. Methoxylated isoflavones, cajanin and isoformononetin, have non-estrogenic bone forming effect via differential mitogen activated protein kinase (MAPK) signaling. J Cell Biochem. John Wiley & Sons, Ltd. 2009;108:388–99.

Article  CAS  Google Scholar 

Maurya R, Yadav DK, Singh G, Bhargavan B, Murthy PN, Sahai M, Singh MM. Osteogenic activity of constituents from Butea monosperma. Bioorg Medicinal Chem Lett. 2009 Feb 1;19(3):610–3.

Srivastava K, Tyagi AM, Khan K, Dixit M, Lahiri S, Kumar A, Changkija B, Khan MP, Nagar GK, Yadav DK, Maurya R. Isoformononetin, a methoxydaidzein present in medicinal plants, reverses bone loss in osteopenic rats and exerts bone anabolic action by preventing osteoblast apoptosis. Phytomed. 2013 Apr 15;20(6):470–80.

Raju KSR, Rashid M, Gundeti M, Taneja I, Malik MY, Singh SK, et al. LC-ESI-MS/MS method for the simultaneous determination of isoformononetin, daidzein, and equol in rat plasma: Application to a preclinical pharmacokinetic study. J Chromatogr B Anal Technol Biomed Life Sci. Elsevier BV. 2019;1129:121776.

Article  CAS  Google Scholar 

Tadros T, Izquierdo P, Esquena J, Solans C. Formation and stability of nano-emulsions. Adv Coll Inter Sci. 2004 May 20;108:303–18.

Anton N, Vandamme TF. Nano-emulsions and micro-emulsions: Clarifications of the critical differences. Pharmaceutical research Pharm Res. 2011;28:978–85.

CAS  PubMed  Google Scholar 

Anton N, Vandamme TF. The universality of low-energy nano-emulsification. Int J Pharm. 2009;377:142–7.

Article  CAS  PubMed  Google Scholar 

Jaiswal M, Dudhe R, Sharma PK. Nanoemulsion: An advanced mode of drug delivery system. 3 Biotech. 2015;5:123–7.

Article  PubMed  Google Scholar 

Thakur A, Walia K, Kumar SLH. Nanoemulsion in enhancement of bioavailability of poorly soluble drugs: A review. Int Res J. 2013;4:15–25.

CAS  Google Scholar 

Lawrence MJ, Rees GD. Microemulsion-based media as novel drug delivery systems. Adv Drug Deliv Rev. 2012;64:175–93.

Article  Google Scholar 

Zainol S, Basri M, Bin Basri H, Shamsuddin AF, Abdul-Gani SS, Karjiban RA, et al. Formulation optimization of a palm-based nanoemulsion system containing levodopa. Int J Mol Sci. 2012;13:13049–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nagi A, Iqbal B, Kumar S, Sharma S, Ali J, Baboota S. Quality by design based silymarin nanoemulsion for enhancement of oral bioavailability. J Drug Deliv Sci Technol. 2017 Aug 1;40:35–44.

Sharma S, Sahni JK, Ali J, Baboota S. Effect of high-pressure homogenization on formulation of TPGS loaded nanoemulsion of rutin–pharmacodynamic and antioxidant studies. Taylor & Francis. Informa Healthcare USA, Inc. 2015;22:541–51.

CAS  Google Scholar 

Sharma S, Sahni JK, Ali J, Baboota S. Effect of high-pressure homogenization on formulation of TPGS loaded nanoemulsion of rutin - pharmacodynamic and antioxidant studies. Drug Deliv. 2015;22:541–51.

Article  CAS  PubMed  Google Scholar 

Shafiq S, Shakeel F, Talegaonkar S, Ahmad FJ, Khar RK, Ali M. Development and bioavailability assessment of ramipril nanoemulsion formulation. Eur J Pharm Biopharm. 2007;66:227–43.

Article  CAS  PubMed  Google Scholar 

Chaudhari PM, Kuchekar MA. Development and evaluation of nanoemulsion as a carrier for topical delivery system by box-behnken design. Asian J Pharm Clin Res. 2018;11:286–93.

Article  Google Scholar 

Kumar K, Singh L, Mishra S, Singh VK, Author C. Prepation and optimization of nanoemulsion formulations of antihypertensive drug Carvedilol. Eur J Mol Clin Med. 2018;05:282–90.

Google Scholar 

Lv Y, He H, Qi J, Lu Y, Zhao W, Dong X, Wu W. Visual validation of the measurement of entrapment efficiency of drug nanocarriers. Intern J Pharm. 2018 Aug 25;547(1–2):395–403.

Singh SK, Rashid M, Bhalala K, Malik Y, Chaturvedi S, Raju KS, Sultana N, Mitra K, Gayen JR, Wahajuddin M. A novel nanosized phospholipid complex of Biochanin A for improving oral bioavailability: Preparation and in-vitro/in-vivo characterizations. J Drug Deliv Sci Technol. 2021 Feb 1;61:102254.

Singh D, SM Rawat M, Semalty A, Semalty M. Rutin-phospholipid complex: an innovative technique in novel drug delivery system-NDDS. Curr Drug Deliv. 2012 May 1;9(3):305–14.

Mahour R, Sahni JK, Sharma S, Kumar S, Ali J, Baboota S. Nanoemulsion as a tool for improvement of cilostazol oral bioavailability. J Mole Liq. 2015 Dec 1;212:792–8.

Garg A, Bhalala K, Tomar DS, Wahajuddin,. In-situ single pass intestinal permeability and pharmacokinetic study of developed lumefantrine loaded solid lipid nanoparticles. Int J Pharm. Elsevier BV. 2017;516:120–30.

Article  CAS  Google Scholar 

Agarwal A, Wahajuddin M, Chaturvedi S, Singh SK, Rashid M, Garg R, Chauhan D, Sultana N, Gayen JR. Formulation and Characterization of Phytosomes as Drug Delivery System of Formononetin: An Effective Anti-Osteoporotic Agent. Curr Drug Deliv. 2023.

Kaplan AB, Cetin M, Orgul D, Taghizadehghalehjoughi A, Hacımuftuoglu A, Hekimoglu S. Formulation and in vitro evaluation of topical nanoemulsion and nanoemulsion-based gels containing daidzein. J Drug DelivSci Technol. 2019 Aug 1;52:189–203.

Teixeira MC, Severino P, Andreani T, Boonme P, Santini A, Silva AM, Souto EB. D-α-tocopherol nanoemulsions: Size properties, rheological behavior, surface tension, osmolarity and cytotoxicity. Saudi Pharm J. 2017 Feb 1;25(2):231–5.

Wahajuddin, Raju KS, Singh SP, Taneja I. Investigation of the functional role of P-glycoprotein in limiting the oral bioavailability of lumefantrine. Antimicro Agents Chem. 2014 Jan;58(1):489–94.

Zakeri-Milani P, Valizadeh H, Tajerzadeh H, Azarmi Y, Islambolchilar Z, Barzegar S, Barzegar-Jalali M. Predicting human intestinal permeability using single-pass intestinal perfusion in rat. J Pharmacy Pharm Sci. 2007;10(3):368–79.

Shakeel F, Baboota S, Ahuja A, Ali J, Aqil M, Shafiq S. Nanoemulsions as vehicles for transdermal delivery of aceclofenac. Aaps Pharmscitech. 2007 Oct;8:191–9.

Swarbrick J. Encyclopedia of Pharmaceutical Technology: Volume 6. CRC press; 2013 Jul 1.

Benita S, Levy MY. Submicron emulsions as colloidal drug carriers for intravenous administration: comprehensive physicochemical characterization. J Pharm Sci. 1993 Nov 1;82(11):1069–79.

Tamilvanan S. Formulation of multifunctional oil-in-water nanosized emulsions for active and passive targeting of drugs to otherwise inaccessible internal organs of the human body. Intern J Pharm. 2009 Oct 20;381(1):62–76.

Tamilvanan S, Benita S. The potential of lipid emulsion for ocular delivery of lipophilic drugs. Euro J Pharm Biopharm. 2004 Sep 1;58(2):357–68.

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