LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA

Anczuków O et al (2015) SRSF1-regulated alternative splicing in breast cancer. Mol Cell 60:105–117

Article  PubMed  PubMed Central  Google Scholar 

Chang X et al (2023) MLXIPL promotes the migration, invasion, and glycolysis of hepatocellular carcinoma cells by phosphorylation of mTOR. BMC Cancer 23:176

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Z et al (2017) A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease. Lipids Health Dis 16:203

Article  PubMed  PubMed Central  Google Scholar 

Cobbina E, Akhlaghi F (2017) Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters. Drug Metab Rev 49:197–211

Article  CAS  PubMed  PubMed Central  Google Scholar 

Das S et al (2012) Oncogenic splicing factor SRSF1 is a critical transcriptional target of MYC. Cell Rep 1:110–117

Article  CAS  PubMed  PubMed Central  Google Scholar 

Di Mauro S et al (2019) Serum coding and non-coding RNAs as biomarkers of NAFLD and fibrosis severity. Liver Int 39:1742–1754

Article  PubMed  PubMed Central  Google Scholar 

Ding X et al (2020) Chicoric acid ameliorates nonalcoholic fatty liver disease via the AMPK/Nrf2/NFκB signaling pathway and restores gut microbiota in high-fat-diet-fed mice. Oxid Med Cell Longev 2020:9734560

Article  PubMed  PubMed Central  Google Scholar 

Fu C et al (2021) The splicing factor SRSF1 stabilizes the mRNA of TSLP to enhance acute lung injury. Cell Immunol 362:104299

Article  CAS  PubMed  Google Scholar 

Ganesh S, Rustgi VK (2016) Current pharmacologic therapy for nonalcoholic fatty liver disease. Clin Liver Dis 20:351–364

Article  PubMed  Google Scholar 

Gao JZ et al (2016) Long non-coding RNA HOTAIR is a marker for hepatocellular carcinoma progression and tumor recurrence. Oncol Lett 11:1791–1798

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guo B et al (2021) LncRNA HOTAIR regulates the lipid accumulation in non-alcoholic fatty liver disease via miR-130b-3p/ROCK1 axis. Cell Signal 90:110190

Article  PubMed  Google Scholar 

Hou W, Bonkovsky HL (2013) Non-coding RNAs in hepatitis C-induced hepatocellular carcinoma: dysregulation and implications for early detection, diagnosis and therapy. World J Gastroenterol 19:7836–7845

Article  PubMed  PubMed Central  Google Scholar 

Hu MJ, Long M, Dai RJ (2021) Acetylation of H3K27 activated lncRNA NEAT1 and promoted hepatic lipid accumulation in non-alcoholic fatty liver disease via regulating miR-212–5p/GRIA3. Mol Cell Biochem, pp 1–13

Huang SF et al (2021) LncRNAs as therapeutic targets and potential biomarkers for lipid-related diseases. Front Pharmacol 12:729745

Article  CAS  PubMed  PubMed Central  Google Scholar 

Iizuka K (2013) Recent progress on the role of ChREBP in glucose and lipid metabolism. Endocr J 60:543–555

Article  CAS  PubMed  Google Scholar 

Iizuka K, Takao K, Yabe D (2020) ChREBP-mediated regulation of lipid metabolism: involvement of the gut microbiota, liver, and adipose tissue. Front Endocrinol (Lausanne) 11:587189

Article  PubMed  Google Scholar 

Jiang W et al (2022) SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1. Atherosclerosis 340:1–11

Article  CAS  PubMed  Google Scholar 

Lei Y et al (2020) Hepatic carbohydrate response element binding protein activation limits nonalcoholic fatty liver disease development in a mouse model for glycogen storage disease type 1a. Hepatology 72:1638–1653

Article  CAS  PubMed  Google Scholar 

Li G et al (2020) Long non-coding RNA-H19 stimulates osteogenic differentiation of bone marrow mesenchymal stem cells via the microRNA-149/SDF-1 axis. J Cell Mol Med 24:4944–4955

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Y et al (2021) TREM2 Regulates High Glucose-Induced Microglial Inflammation via the NLRP3 Signaling Pathway. Brain Sci 11:896

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lu L et al (2012) Association of large noncoding RNA HOTAIR expression and its downstream intergenic CpG island methylation with survival in breast cancer. Breast Cancer Res Treat 136:875–883

Article  CAS  PubMed  Google Scholar 

Lv L et al (2023) Long non-coding RNA SNHG4 enhances RNF14 mRNA stability to promote the progression of colorectal cancer by recruiting TAF15 protein. Apoptosis 28:14–431

Article  Google Scholar 

Ma M et al (2020) The lncRNA Gm15622 stimulates SREBP-1c expression and hepatic lipid accumulation by sponging the miR-742-3p in mice. J Lipid Res 61:1052–1064

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mao T et al (2019) Silencing lncRNA HOTAIR declines synovial inflammation and synoviocyte proliferation and promotes synoviocyte apoptosis in osteoarthritis rats by inhibiting Wnt/β-catenin signaling pathway. Cell Cycle 18:3189–3205

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ni W et al (2019) Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m(6)A reader YTHDF3. Mol Cancer 18:143

Article  PubMed  PubMed Central  Google Scholar 

Park MJ et al (2014) High glucose-induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: the possible role in the development of diabetic nephropathy. J Biol Chem 289:13519–13530

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stoeckman AK, Ma L, Towle HC (2004) Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes. J Biol Chem 279:15662–15669

Article  CAS  PubMed  Google Scholar 

Sun Y, Hu ZQ (2020) LncRNA HOTAIR aggravates myocardial ischemia-reperfusion injury by sponging microRNA-126 to upregulate SRSF1. Eur Rev Med Pharmacol Sci 24:9046–9054

CAS  PubMed  Google Scholar 

Takahashi Y et al (2015) Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Gastroenterol 21:3777–3785

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang Y et al (2015) Transcriptional regulation of hepatic lipogenesis. Nat Rev Mol Cell Biol 16:678–689

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang L et al (2019) FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c. Lipids Health Dis 18:197

Article  PubMed  PubMed Central  Google Scholar 

Wang H et al (2020) Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. J Cell Mol Med 24:1399–1412

Article  CAS  PubMed  Google Scholar 

Xie N et al (2017) SRSF1 promotes vascular smooth muscle cell proliferation through a Δ133p53/EGR1/KLF5 pathway. Nat Commun 8:16016

Article  ADS  PubMed  PubMed Central  Google Scholar 

Ye Y et al (2021) RNA binding protein serine/arginine splicing factor 1 promotes the proliferation, migration and invasion of hepatocellular carcinoma by interacting with RecQ protein-like 4 mRNA. Bioengineered 12:6144–6154

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhan H et al (2020) Upregulation of Mlxipl induced by cJun in the spinal dorsal horn after peripheral nerve injury counteracts mechanical allodynia by inhibiting neuroinflammation. Aging (albany NY) 12:11004–11024

Article  CAS  PubMed  Google Scholar 

Zhang HJ et al (2017) LncRNA HOTAIR alleviates rheumatoid arthritis by targeting miR-138 and inactivating NF-κB pathway. Int Immunopharmacol 50:283–290

Article  CAS  PubMed  Google Scholar 

Zhao XY et al (2018a) Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis. Nat Commun 9:2986

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Zhao W et al (2018b) LncRNA HOTAIR influences cell growth, migration, invasion, and apoptosis via the miR-20a-5p/HMGA2 axis in breast cancer. Cancer Med 7:842–855

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