Arciniegas E, Neves CY, Carrillo LM, Zambrano EA, Ramirez R (2005) Endothelial-mesenchymal transition occurs during embryonic pulmonary artery development. Endothelium 12:193–200
Article CAS PubMed Google Scholar
Arciniegas E, Frid MG, Douglas IS, Stenmark KR (2007) Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 293:L1-8
Article CAS PubMed Google Scholar
Bijkerk R, de Bruin RG, van Solingen C et al (2012) MicroRNA-155 functions as a negative regulator of RhoA signaling in TGF-beta-induced endothelial to mesenchymal transition. Microrna 1:2–10
Article CAS PubMed Google Scholar
Das S, Kumar M, Negi V et al (2014) MicroRNA-326 regulates profibrotic functions of transforming growth factor-beta in pulmonary fibrosis. Am J Respir Cell Mol Biol 50:882–892
Article PubMed PubMed Central Google Scholar
Dekker RJ, van Thienen JV, Rohlena J et al (2005) Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes. Am J Pathol 167:609–618
Article CAS PubMed PubMed Central Google Scholar
Friedman SL (2008) Mechanisms of hepatic fibrogenesis. Gastroenterology 134:1655–1669
Article CAS PubMed Google Scholar
Galasso M, Sana ME, Volinia S (2010) Non-coding RNAs: a key to future personalized molecular therapy? Genome Med 2:12
Article PubMed PubMed Central Google Scholar
Goumans MJ, van Zonneveld AJ, ten Dijke P (2008) Transforming growth factor beta-induced endothelial-to-mesenchymal transition: a switch to cardiac fibrosis? Trends Cardiovasc Med 18:293–298
Article CAS PubMed Google Scholar
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ (2006) miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34:D140–D144
Article CAS PubMed Google Scholar
Hu JL, Wang W, Lan XL et al (2019) CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer. Mol Cancer 18:91
Article CAS PubMed PubMed Central Google Scholar
Huang R, Bai C, Liu X et al (2021) The p53/RMRP/miR122 signaling loop promotes epithelial-mesenchymal transition during the development of silica-induced lung fibrosis by activating the notch pathway. Chemosphere 263:128133
Article CAS PubMed Google Scholar
Huddleson JP, Ahmad N, Srinivasan S, Lingrel JB (2005) Induction of KLF2 by fluid shear stress requires a novel promoter element activated by a phosphatidylinositol 3-kinase-dependent chromatin-remodeling pathway. J Biol Chem 280:23371–23379
Article CAS PubMed Google Scholar
Hwang HW, Mendell JT (2007) MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 96:R40–R44
Kawanami D, Mahabeleshwar GH, Lin Z et al (2009) Kruppel-like factor 2 inhibits hypoxia-inducible factor 1alpha expression and function in the endothelium. J Biol Chem 284:20522–20530
Article CAS PubMed PubMed Central Google Scholar
Ke TW, Wei PL, Yeh KT, Chen WT, Cheng YW (2015) MiR-92a promotes cell metastasis of colorectal Cancer through PTEN-Mediated PI3K/AKT pathway. Ann Surg Oncol 22:2649–2655
Konaka T, Kawami M, Yamamoto A, Yumoto R, Takano M (2020) miR-484: a possible Indicator of Drug-Induced Pulmonary Fibrosis. J Pharm Pharm Sci 23:486–495
Article CAS PubMed Google Scholar
Lau NC, Lim LP, Weinstein EG, Bartel DP (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294:858–862
Article CAS PubMed Google Scholar
Li M, Zhang M, Chen M et al (2022) KLF2-induced circZKSCAN1 potentiates the tumorigenic properties of clear cell renal cell carcinoma by targeting the miR-1294/PIM1 axis. Cell Cycle 21:1376–1390
Article CAS PubMed PubMed Central Google Scholar
Li J, Jiang JL, Chen YM, Lu WQ (2023) KLF2 inhibits colorectal cancer progression and metastasis by inducing ferroptosis via the PI3K/AKT signaling pathway. J Pathol Clin Res 9:423–435
Article CAS PubMed PubMed Central Google Scholar
Lv Z, Wang Y, Liu YJ et al (2018) NLRP3 inflammasome activation contributes to Mechanical Stretch-Induced endothelial-mesenchymal transition and pulmonary fibrosis. Crit Care Med 46:e49–e58
Article CAS PubMed Google Scholar
Ma H, Pan JS, Jin LX et al (2016) MicroRNA-17 ~ 92 inhibits colorectal cancer progression by targeting angiogenesis. Cancer Lett 376:293–302
Article CAS PubMed Google Scholar
Montes E, Ruiz V, Checa M et al (2012) Renin is an angiotensin-independent profibrotic mediator: role in pulmonary fibrosis. Eur Respir J 39:141–148
Article CAS PubMed Google Scholar
Okayama K, Azuma J, Dosaka N et al (2012) Hepatocyte growth factor reduces cardiac fibrosis by inhibiting endothelial-mesenchymal transition. Hypertension 59:958–965
Article CAS PubMed Google Scholar
Ortiz-Zapater E, Signes-Costa J, Montero P, Roger I (2022) Lung Fibrosis and Fibrosis in the Lungs: Is It All about Myofibroblasts? Biomedicines 10:1423
Article CAS PubMed PubMed Central Google Scholar
Parmar KM, Larman HB, Dai G et al (2006) Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2. J Clin Invest 116:49–58
Article CAS PubMed Google Scholar
Piera-Velazquez S, Li Z, Jimenez SA (2011) Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders. Am J Pathol 179:1074–1080
Article CAS PubMed PubMed Central Google Scholar
Piera-Velazquez S, Mendoza FA, Jimenez SA (2016) Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases. J Clin Med 5:45
Article PubMed PubMed Central Google Scholar
Qin SY, Li B, Chen M, Qin MQ, Liu JM, Lv QL (2022) MiR-32-5p promoted epithelial-to-mesenchymal transition of oral squamous cell carcinoma cells via regulating the KLF2/CXCR4 pathway. Kaohsiung J Med Sci 38:120–128
Article CAS PubMed Google Scholar
Santos-Silva MA, Pires KM, Trajano ET et al (2012) Redox imbalance and pulmonary function in bleomycin-induced fibrosis in C57BL/6, DBA/2, and BALB/c mice. Toxicol Pathol 40:731–741
Article CAS PubMed Google Scholar
Strieter RM, Mehrad B (2009) New mechanisms of pulmonary fibrosis. Chest 136:1364–1370
Article PubMed PubMed Central Google Scholar
Tang H, Mao J, Ye X et al (2020) SHIP-1, a target of miR-155, regulates endothelial cell responses in lung fibrosis. FASEB J 34:2011–2023
Article CAS PubMed Google Scholar
Tian X, Pu WT, Zhou B (2015) Cellular origin and developmental program of coronary angiogenesis. Circ Res 116:515–530
Article CAS PubMed PubMed Central Google Scholar
Ubil E, Duan J, Pillai IC et al (2014) Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature 514:585–590
Article CAS PubMed PubMed Central Google Scholar
Wang D, Liu Z, Yan Z et al (2020) MiRNA-155-5p inhibits epithelium-to-mesenchymal transition (EMT) by targeting GSK-3beta during radiation-induced pulmonary fibrosis. Arch Biochem Biophys 697:108699
Wani MA, Means RT Jr, Lingrel JB (1998) Loss of LKLF function results in embryonic lethality in mice. Transgenic Res 7:229–238
Article CAS PubMed Google Scholar
Williams AH, Liu N, van Rooij E, Olson EN (2009) MicroRNA control of muscle development and disease. Curr Opin Cell Biol 21:461–469
Article CAS PubMed PubMed Central Google Scholar
Wu X, Piper-Hunter MG, Crawford M et al (2009) MicroRNAs in the pathogenesis of Lung Cancer. J Thorac Oncol 4:1028–1034
留言 (0)