Metagenomic Next-generation Sequencing May be a Tool for Timely Diagnosis of Seronegative and Primary Toxoplasma Infection After Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report and Literature Review

*From the Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China

†Department of Hematology, The Peoples Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, People’s Republic of China.

Accepted for publication October 3, 2023

The authors have no funding or conflicts of interest to disclose.

Q.L. and Y.C. contributed equally to this manuscript.

Q.L. conceptualized and designed the study, drafted the initial manuscript and revised the manuscript. J.W. and L.M. collected the patients’ clinical information, provided technical support for this work and revised the manuscript. G.W. and Y.C. performed the table analysis, designed the study and reviewed the manuscript. All authors contributed to the manuscript and approved the submitted version.

The datasets presented in this article are not readily available because of concerns regarding participant/patient anonymity. Requests to access the datasets should be directed to [email protected].

Written informed consent has been provided by the patient for the case details and images to be published. Details of the case can be published without institutional approval.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (www.pidj.com).

Address for correspondence: Gaoxiang Wang, PhD, Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People’s Republic of China. E-mail: [email protected].

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