Kelly DM, Jones TH (2013) Testosterone: a metabolic hormone in health and disease. J Endocrinol 217(3):R25-45

Article  PubMed  CAS  Google Scholar 

Rastrelli G, Corona G, Maggi M (2018) Testosterone and sexual function in men. Maturitas 112:46–52

Article  PubMed  CAS  Google Scholar 

McHenry J, Carrier N, Hull E, Kabbaj M (2014) Sex differences in anxiety and depression: role of testosterone. Front Neuroendocrinol 35(1):42–57

Article  PubMed  CAS  Google Scholar 

Sharma A, Minhas S, Dhillo WS, Jayasena CN (2021) Male infertility due to testicular disorders. J Clin Endocrinol Metab 106(2):e442–e459

Article  PubMed  Google Scholar 

Oduwole OO, Huhtaniemi IT, Misrahi M (2021) The roles of luteinizing hormone, follicle-stimulating hormone and testosterone in spermatogenesis and folliculogenesis revisited. Int J Mol Sci 22(23):12735

Article  PubMed  PubMed Central  CAS  Google Scholar 

Rajfer J (2000) Relationship between testosterone and erectile dysfunction. Rev Urol 2(2):122–128

PubMed  PubMed Central  CAS  Google Scholar 

Kloner RA, Carson C 3rd, Dobs A, Kopecky S, Mohler ER 3rd (2016) Testosterone and cardiovascular disease. J Am Coll Cardiol 67(5):545–557

Article  PubMed  CAS  Google Scholar 

Bhasin S, Valderrábano RJ, Gagliano-Jucá T. Age-related changes in the male reproductive system. In: Feingold KR, Anawalt B, Blackman MR, et al., eds. Endotext. South Dartmouth (MA): MDText.com, Inc.; February 10, 2022

Linderman JK, O’Hara R, Ordway J (2020) Effect of special operations training on testosterone, lean body mass, and strength and the potential for therapeutic testosterone replacement: a review of the literature. J Spec Oper Med 20(1):94–100

Article  PubMed  Google Scholar 

Khodamoradi K, Khosravizadeh Z, Seetharam D, Mallepalli S, Farber N, Arora H (2022) The role of leptin and low testosterone in obesity. Int J Impot Res 34(7):704–713

Article  PubMed  Google Scholar 

Corona G, Vena W, Pizzocaro A, Giagulli VA, Francomano D, Rastrelli G, Mazziotti G, Aversa A, Isidori AM, Pivonello R, Vignozzi L, Mannucci E, Maggi M, Ferlin A (2022) Testosterone supplementation and bone parameters: a systematic review and meta-analysis study. J Endocrinol Invest 45(5):911–926

Article  PubMed  CAS  Google Scholar 

Corona G, Guaraldi F, Rastrelli G, Sforza A, Maggi M (2021) Testosterone deficiency and risk of cognitive disorders in aging males. World J Mens Health 39(1):9–18

Article  PubMed  Google Scholar 

Pintana H, Chattipakorn N, Chattipakorn S (2015) Testosterone deficiency, insulin-resistant obesity and cognitive function. Metab Brain Dis 30(4):853–876

Article  PubMed  CAS  Google Scholar 

Davis SR, Wahlin-Jacobsen S (2015) Testosterone in women–the clinical significance. Lancet Diabetes Endocrinol 3(12):980–992

Article  PubMed  CAS  Google Scholar 

Smith T, Batur P (2021) Prescribing testosterone and DHEA: the role of androgens in women. Cleve Clin J Med 88(1):35–43

Article  PubMed  Google Scholar 

Le J, Thomas N, Gurvich C (2020) Cognition, the menstrual cycle, and premenstrual disorders: a review. Brain Sci 10(4):198

Article  PubMed  PubMed Central  CAS  Google Scholar 

Stanczyk FZ (2006) Diagnosis of hyperandrogenism: biochemical criteria. Best Pract Res Clin Endocrinol Metab 20(2):177–191

Article  PubMed  CAS  Google Scholar 

Goldman AL, Bhasin S, Wu FCW, Krishna M, Matsumoto AM, Jasuja R (2017) A reappraisal of testosterone’s binding in circulation: physiological and clinical implications. Endocr Rev 38(4):302–324

Article  PubMed  PubMed Central  Google Scholar 

Vermeulen A (1973) Testosterone in plasma. A physiopathological study. Verh - Geneeskd Belg 35:95–180

CAS  Google Scholar 

Bhasin S, Brito JP, Cunningham GR, Hayes FJ, Hodis HN, Matsumoto AM, Snyder PJ, Swerdloff RS, Wu FC, Yialamas MA (2018) Testosterone therapy in men with hypogonadism: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 103(5):1715–1744

Article  PubMed  Google Scholar 

Isidori AM, Aversa A, Calogero A, Ferlin A, Francavilla S, Lanfranco F, Pivonello R, Rochira V, Corona G, Maggi M (2022) Adult- and late-onset male hypogonadism: the clinical practice guidelines of the Italian Society of Andrology and Sexual Medicine (SIAMS) and the Italian Society of Endocrinology (SIE). J Endocrinol Invest 45(12):2385–2403

Article  PubMed  PubMed Central  CAS  Google Scholar 

Vermeulen A (2005) Hormonal cut-offs of partial androgen deficiency: a survey of androgen assays. J Endocrinol Invest 28(3 Suppl):28–31

PubMed  CAS  Google Scholar 

Plebani M (2006) Errors in clinical laboratories or errors in laboratory medicine? Clin Chem Lab Med 44(6):750–759

Article  PubMed  CAS  Google Scholar 

Casagrande A, Fabris F, Girometti R (2020) Beyond kappa: an informational index for diagnostic agreement in dichotomous and multivalue ordered-categorical ratings. Med Biol Eng Comput 58(12):3089–3099

Article  PubMed  PubMed Central  Google Scholar 

Fiers T, Wu F, Moghetti P, Vanderschueren D, Lapauw B, Kaufman JM (2018) Reassessing free-testosterone calculation by liquid chromatography-tandem mass spectrometry direct equilibrium dialysis. J Clin Endocrinol Metab 103(6):2167–2174

Article  PubMed  Google Scholar 

Kacker R, Hornstein A, Morgentaler A (2013) Free testosterone by direct and calculated measurement versus equilibrium dialysis in a clinical population. Aging Male 16(4):164–168

Article  PubMed  CAS  Google Scholar 

Rosner W, Auchus RJ, Azziz R, Sluss PM, Raff H (2007) Position statement: utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement. J Clin Endocrinol Metab 92(2):405–413

Article  PubMed  CAS  Google Scholar 

Matsumoto AM, Bremner WJ (2004) Serum testosterone assays–accuracy matters. J Clin Endocrinol Metab 89(2):520–524

Article  PubMed  CAS  Google Scholar 

Tosi F, Fiers T, Kaufman JM, Dall’Alda M, Moretta R, Giagulli VA, Bonora E, Moghetti P (2016) Implications of androgen assay accuracy in the phenotyping of women with polycystic ovary syndrome. J Clin Endocrinol Metab 101(2):610–618

Article  PubMed  CAS  Google Scholar