Carreno M, Lüders HO. Chap. 47: General principles of presurgical evaluation. In: Lüders HO, editor. Textbook of epilepsy surgery. 2008. p. 409–22.

Ebersole JS, Ebersole SM. Combining MEG and EEG source modeling in epilepsy evaluations. J Clin Neurophysiol. 2010;27:360–71. https://doi.org/10.1097/WNP.0b013e318201ffc4.

Article  PubMed  Google Scholar 

Piastra MC, Nu¨ßing A, Vorwerk J, Clerc M, Engwer C, Wolters CH. A comprehensive study on electroencephalography and magnetoencephalography sensitivity to cortical and subcortical sources. Hum Brain Mapp. 2021;42:978–92. https://doi.org/10.1002/hbm.25272. A detailed modeling study comparing relative sensitivities of EEG and MEG for different brain regions. EEG was found to more sensitive for radial and deep sources, and MEG more sensitive for tangential sources.

Article  PubMed  Google Scholar 

Mikuni N, Nagamine T, Ikeda A, Terada K, Taki W, Kimura J, Kikuchi H, Shibasaki H. Simultaneous recording of epileptiform discharges by MEG and subdural electrodes in temporal lobe epilepsy. Neuroimage. 1997;5:298–306. https://doi.org/10.1006/nimg.1997.0272.

Article  PubMed  CAS  Google Scholar 

Okada YC, Lahteenmäki A, Xu C. Experimental analysis of distortion of magnetoencephalography signals by the skull. Clin Neurophysiol. 1999;110:230–8. https://doi.org/10.1016/S0013-4694(98)00099-6.

Article  PubMed  CAS  Google Scholar 

Okada Y, Lahteenmaki A, Xu C. Comparison of MEG and EEG on the basis of somatic evoked responses elicited by stimulation of the snout in the juvenile swine. Clin Neurophysiol. 1999;110:214–29. https://doi.org/10.1016/S0013-4694(98)00111-4.

Article  PubMed  CAS  Google Scholar 

Hämäläinen MS, Hari R, Ilmoniemi RJ, Knuutila J, Lounasmaa OV. Magnetoencephalography—theory, instrumentation, and applications to noninvasive studies of the working human brain. Rev Mod Phys. 1993;65:413–515.

Article  Google Scholar 

Tamilia E, AlHilani M, Tanaka N, Tsuboyama M, Peters JM, Grant PE, Madsen JR, Stufflebeam SM, Pearl PL, Papadelis C. Assessing the localization accuracy and clinical utility of electric and magnetic source imaging in children with epilepsy. Clin Neurophysiol. 2019;130:491–504. https://doi.org/10.1016/j.clinph.2019.01.009. A study comparing localization accuracy for EEG and MEG, utilizing intracranial EEG and resection as the ground truth. MEG was found to have smaller localization error than both conventional and high-density scalp EEG.

Article  PubMed  PubMed Central  Google Scholar 

Bagić AI, Knowlton RC, Rose DF, Ebersole JS. American Clinical Magnetoencephalography Society clinical practice guideline 1: recording and analysis of spontaneous cerebral activity. J Clin Neurophysiol. 2011;0:1. https://doi.org/10.1097/WNP.0b013e3182272fed.

Article  Google Scholar 

Burgess RC, Funke ME, Bowyer SM, Lewine JD, Kirsch HE, Bagić AI. American Clinical Magnetoencephalography Society clinical practice guideline 2: presurgical functional brain mapping using magnetic evoked fields. J Clin Neurophysiol. 2011;28:1. https://doi.org/10.1097/WNP.0b013e3182272ffe.

Article  Google Scholar 

Bagić AI, Knowlton RC, Rose DF, Ebersole JS. American Clinical Magnetoencephalography Society clinical practice guideline 3. J Clin Neurophysiol. 2011;0:1. https://doi.org/10.1097/WNP.0b013e3182272fed.

Article  Google Scholar 

Bagić AI, Knowlton RC, Rose DF, Ebersole JS. American Clinical Magnetoencephalography Society clinical practice guideline 4. J Clin Neurophysiol. 2011;0:1. https://doi.org/10.1097/WNP.0b013e3182272fed.

Article  Google Scholar 

Tenney JR, Fujiwara H, Rose DF. The value of source localization for clinical magnetoencephalography: beyond the equivalent current dipole. J Clin Neurophysiol. 2020;37:537–44. https://doi.org/10.1097/WNP.0000000000000487.

Article  PubMed  Google Scholar 

Bowyer SM, Zillgitt AJ, Greenwald M, Lajiness-O’Neill R. Language mapping with magnetoencephalography: an update on the current state of clinical research and practice with considerations for clinical practice guidelines. J Clin Neurophysiol. 2020;37:554–63. https://doi.org/10.1097/WNP.0000000000000489.

Article  PubMed  Google Scholar 

De Tiège X, Bourguignon M, Piitulainen H, Jousmäki V. Sensorimotor mapping with MEG: an update on the current state of clinical research and practice with considerations for clinical practice guidelines. J Clin Neurophysiol. 2020;37:564–73. https://doi.org/10.1097/WNP.0000000000000481.

Article  PubMed  Google Scholar 

Zillgitt AJ, Barkley GL, Bowyer SM. Visual mapping with magnetoencephalography: an update on the current state of clinical research and practice with considerations for clinical practice guidelines. J Clin Neurophysiol. 2020;37:585–91. https://doi.org/10.1097/WNP.0000000000000483.

Article  PubMed  Google Scholar 

Shvarts V, Mäkelä JP. Auditory mapping with MEG: an update on the current state of clinical research and practice with considerations for clinical practice guidelines. J Clin Neurophysiol. 2020;37:574–84. https://doi.org/10.1097/WNP.0000000000000518.

Article  PubMed  Google Scholar 

Laohathai C, Ebersole JS, Mosher JC, Bagić AI, Sumida A, Von Allmen G, Funke ME. Practical fundamentals of clinical MEG interpretation in epilepsy. Front Neurol. 2021;12:1–22. https://doi.org/10.3389/fneur.2021.722986. An excellent overview of clinical MEG as used for epilepsy.

Article  Google Scholar 

Fischer MJ, Scheler G, Stefan H. Utilization of magnetoencephalography results to obtain favourable outcomes in epilepsy surgery. Brain. 2005;128:153–7. https://doi.org/10.1093/brain/awh333.

Article  PubMed  Google Scholar 

Mouthaan BE, Rados M, Boon PAJM, Carrette E, Diehl B, Jung J, Kimiskidis VK, Kobulashvili T, Kuchukhidze G, Larsson PG, Leitinger M, Ryvlin P, Rugg-Gunn F, Seeck M, Vulli’emoz S, Huiskamp G, Lei-jten FSS, Van Eijsden P, Trinka E, Braun KPJ. Diagnostic accuracy of interictal source imaging in presurgical epilepsy evaluation: a systematic review from the E-PILEPSY consortium. Clin Neurophysiol. 2019;130:845–55. https://doi.org/10.1016/j.clinph.2018.12.016. A meta-analysis of several studies comparing the relative contributions of EEG and MEG to epilepsy presurgical evaluation. No statistical difference was found between the contributions of the two modalities.

Article  PubMed  Google Scholar 

Papanicolaou AC, Pataraia E, Billingsley-Marshall RL, Castillo EM, Wheless JW, Swank P, Breier JI, Sarkari S, Simos PG. Toward the substitution of invasive electroencephalography in epilepsy surgery. J Clin Neurophysiol. 2005;22:231–7. https://doi.org/10.1097/01.WNP.0000172255.62072.E8.

Article  PubMed  Google Scholar 

Knowlton RC, Elgavish RA, Bartolucci A, Ojha B, Limdi N, Blount J, Burneo JG, Ver Hoef L, Paige L, Faught E, Kankirawatana P, Riley K, Kuzniecky R. Functional imaging: II. Prediction of epilepsy surgery outcome. Ann Neurol. 2008;64:35–41. https://doi.org/10.1002/ana.21419.

Article  PubMed  Google Scholar 

Jeong W, Chung CK, Kim JS. Magnetoencephalography interictal spike clustering in relation with surgical outcome of cortical dysplasia. J Korean Neurosurg Soc. 2012;52:466–71. https://doi.org/10.3340/jkns.2012.52.5.466.

Article  PubMed  PubMed Central  Google Scholar 

Schneider F, Irene Wang Z, Alexopoulos AV, Almubarak S, Kakisaka Y, Jin K, Nair D, Mosher JC, Najm IM, Burgess RC. Magnetic source imaging and ictal SPECT in MRI-negative neocortical epilepsies: additional value and comparison with intracranial EEG. Epilepsia. 2013;54:359–69. https://doi.org/10.1111/epi.12004.

Article  PubMed  Google Scholar 

Wilenius J, Medvedovsky M, Gaily E, Metsähonkala L, Mäkelä JP, Pae-tau A, Valanne L, Paetau R. Interictal MEG reveals focal cortical dysplasias: special focus on patients with no visible MRI lesions. Epilepsy Res. 2013;105:337–48. https://doi.org/10.1016/j.eplepsyres.2013.02.023.

Article  PubMed  Google Scholar 

Almubarak S, Alexopoulos A, Von-Podewils F, Wang ZI, Kakisaka Y, Mosher JC, Bulacio J, González-Martínez J, Bingaman W, Burgess RC. The correlation of magnetoencephalography to intracranial EEG in localizing the epileptogenic zone: a study of the surgical resection outcome. Epilepsy Res. 2014;108:1581–90. https://doi.org/10.1016/j.eplepsyres.2014.08.016.

Article  PubMed  Google Scholar 

Mu J, Rampp S, Carrette E, Roessler K, Sommer B, Schmitt FC, De Tiège X, Hamer HM, Boon PAJM, Pauli E, Blümcke I, Zhou D, Buchfelder M, Stefan H. Clinical relevance of source location in frontal lobe epilepsy and prediction of postoperative long-term outcome. Seizure. 2014;23:553–9. https://doi.org/10.1016/j.seizure.2014.04.006.

Article  PubMed  Google Scholar 

Kim H, Kankirawatana P, Killen J, Harrison A, Oh A, Rozzelle C, Blount J, Knowlton R. Magnetic source imaging (MSI) in children with neocortical epilepsy: surgical outcome association with 3D post-resection analysis. Epilepsy Res. 2013;106:164–72. https://doi.org/10.1016/j.eplepsyres.2013.04.004.

Article  PubMed  Google Scholar 

Murakami H, Wang ZI, Marashly A, Krishnan B, Prayson RA, Kakisaka Y, Mosher JC, Bulacio J, Gonzalez-Martinez JA, Bingaman WE, Najm IM, Burgess RC, Alexopoulos AV. Correlating magnetoencephalography to stereo-electroencephalography in patients undergoing epilepsy surgery. Brain a J Neurol. 2016;139:2935–47. https://doi.org/10.1093/brain/aww215.

Article  Google Scholar 

Rampp S, Stefan H, Wu X, Kaltenhauser M, Maess B, Schmitt FC, Wolters CH, Hamer HM, Kasper BS, Schwab S, Doerfler A, Blumcke I, Rössler K, Buchfelder M. Magnetoencephalography for epileptic focus localization in a series of 1000 cases. Brain. 2019;142:3059–71. https://doi.org/10.1093/brain/awz231. A detailed retrospective study of a large cohort of patients who underwent MEG and epilepsy surgery. Extent of resection of MEG IZ was a postive prognostic factor.

Article  PubMed  Google Scholar 

He X, Zhou J, Teng P, Wang X, Guan Y, Zhai F, Li T, Luan G. The impact of MEG results on surgical outcomes in patients with drug-resistant epilepsy associated with focal encephalomalacia: a single-center experience. J Neurol. 2020;267:812–22. https://doi.org/10.1007/s00415-019-09638-w.

Article  PubMed  Google Scholar 

Chourasia N, Quach M, Gavvala J. Insular Magnetoencephalography dipole clusters in patients with refractory focal epilepsy. J Clin Neurophysiol. 2021;38:542–6. https://doi.org/10.1097/WNP.0000000000000718.

Article  PubMed  Google Scholar 

Ntolkeras G, Tamilia E, AlHilani M, Bolton J, Ellen Grant P, Prabhu SP, Madsen JR, Stufflebeam SM, Pearl PL, Papadelis C. Presurgical accuracy of dipole clustering in MRI-negative pediatric patients with epilepsy: validation against intracranial EEG and resection. Clin Neurophysiol. 2022;141:126–38. https://doi.org/10.1016/j.clinph.2021.01.036. This retrospective study evaluated dipole clustering for conventional and high-density scalp EEG as well as MEG. Dipole clustering was found to be a positive prognostic factor for surgical outcome.

Article  PubMed  Google Scholar 

Anand A, Magnotti JF, Smith DN, Gadot R, Najera RA, Hegazy MI, Gavvala JR, Shofty B, Sheth SA. Predictive value of magnetoencephalography in guiding the intracranial implant strategy for intractable epilepsy. J Neurosurg. 2022;137:1237–47. https://doi.org/10.3171/2022.1.JNS212943.

Article  Google Scholar 

Oishi M, Kameyama S, Masuda H, Tohyama J, Kanazawa O, Sasagawa M, Otsubo H. Single and multiple clusters of magnetoencephalographic dipoles in neocortical epilepsy: significance in characterizing the epileptogenic zone. Epilepsia. 2006;47:355–64. https://doi.org/10.1111/j.1528-1167.2006.00428.x.

Article  PubMed