Modulation of Neuronal Damage in DRG by Asprosin in a High-Glucose Environment and Its Impact on miRNA181-a Expression in Diabetic DRG

Ayar A, Ozcan M, Alcin E, Serhatlioglu I, Ozcan S, Kutlu S, Kelestimur H (2014) Oxytocin activates calcium signaling in rat sensory neurons through a protein kinase C-dependent mechanism. J Physiol Biochem 70(1):43–8. https://doi.org/10.1007/s13105-013-0278-z

Bischoff A (1973) Ultrastructural pathology of periperal nervous system in early diabetes. Adv Metab Disord 2. Suppl 2:441–449. https://doi.org/10.1016/b978-0-12-027362-1.50052-2

Chen S, Wang X, Qiu CM, Hou JN, Wei XY, Xiang CX, Tang MY, Zhang R, Pei HF (2019) Study of the role and mechanism of asprosin/spartin pathway in cardiac microvascular endothelial injury induced by diabete mellitus. Sichuan da xue xue bao. Yi xue ban. J Sichuan Univ. Med Sci Ed 50(6):827–834

Cnop M, Welsh N, Jonas JC, Jorns A, Lenzen S, Eizirik DL (2005) Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54(Suppl 2):S97-107. https://doi.org/10.2337/diabetes.54.suppl2.s97

Article  CAS  PubMed  Google Scholar 

Hekim MG, Kelestemur MM, Bulmus FG, Bilgin B, Bulut F, Gokdere E, Ozdede MR, Kelestimur H, Canpolat S, Ozcan M (2021) Asprosin, a novel glucogenic adipokine: a potential therapeutic implication in diabetes mellitus. Arch Physiol Biochem 1–7. https://doi.org/10.1080/13813455.2021.1894178

Kantharidis P, Wang B, Carew RM, Lan HY (2011) Diabetes complications: the microRNA perspective. Diabetes 60(7):1832–1837. https://doi.org/10.2337/db11-0082

Article  CAS  PubMed  PubMed Central  Google Scholar 

Klöting N, Berthold S, Kovacs P, Schön MR, Fasshauer M, Ruschke K, Stumvoll M, Blüher M (2009) MicroRNA expression in human omental and subcutaneous adipose tissue. PLoS ONE 4(3):e4699. https://doi.org/10.1371/journal.pone.0004699

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee T, Yun S, Jeong JH, Jung TW (2019) Asprosin impairs insulin secretion in response to glucose and viability through TLR4/JNK-mediated inflammation. Mol Cell Endocrinol 486:96–104. https://doi.org/10.1016/j.mce.2019.03.001

Article  CAS  PubMed  Google Scholar 

Leong SY, Rao VT, Bin JM, Gris P, Sangaralingam M, Kennedy TE et al (2014) Heterogeneity of oligodendrocyte progenitor cells in adult human brain. Ann Clin Transl Neurol 1:272–283. https://doi.org/10.1002/acn3.55

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li QJ, Chau J, Ebert PJ, Sylvester G, Min H, Liu G, Braich R, Manoharan M, Soutschek J, Skare P, Klein LO, Davis MM, Chen CZ (2007) miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129(1):147–161. https://doi.org/10.1016/j.cell.2007.03.008

Article  CAS  PubMed  Google Scholar 

Liu Y, Song Y, Zhu X (2017) MicroRNA-181a regulates apoptosis and autophagy process in Parkinson's disease by inhibiting p38 mitogen-activated protein kinase (MAPK)/c-Jun N-terminal kinases (JNK) signaling pathways. Med Sci Monit 23:1597–1606. https://doi.org/10.12659/msm.900218

Liu Y, Zhang S, Xue J, Wei Z, Ao P, Shen B, Ding L (2019) CGRP reduces apoptosis of DRG cells induced by high-glucose oxidative stress injury through PI3K/AKT induction of heme oxygenase-1 and Nrf-2 expression. Oxid Med Cell Longev 2019:2053149. https://doi.org/10.1155/2019/2053149

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Y, Zhao Z, Yang F, Gao Y, Song J, Wan Y (2013) microRNA-181a is involved in insulin-like growth factor-1-mediated regulation of the transcription factor CREB1. J Neurochem 126(6):771–780. https://doi.org/10.1111/jnc.12370

Article  CAS  PubMed  Google Scholar 

Lonze BE, Riccio A, Cohen S, Ginty DD (2002) Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron 34(3):371–385. https://doi.org/10.1016/s0896-6273(02)00686-4

Article  CAS  PubMed  Google Scholar 

Lorenzen J, Kumarswamy R, Dangwal S, Thum T (2012) MicroRNAs in diabetes and diabetes-associated complications. RNA Biol 9(6):820–827. https://doi.org/10.4161/rna.20162

Article  CAS  PubMed  Google Scholar 

Lozano-Bartolomé J, Llauradó G, Portero-Otin M, Altuna-Coy A, Rojo-Martínez G, Vendrell J, Jorba R, Rodríguez-Gallego E, Chacón MR (2018) Altered expression of miR-181a-5p and miR-23a-3p is associated with obesity and TNFα-induced insulin resistance. J Clin Endocrinol Metab 103(4):1447–1458. https://doi.org/10.1210/jc.2017-01909

Article  PubMed  Google Scholar 

Maranta F, Cianfanelli L, Cianflone D (2021) Glycaemic control and vascular complications in diabetes mellitus type 2. Adv Exp Med Biol 1307:129–152. https://doi.org/10.1007/5584_2020_514

Article  CAS  PubMed  Google Scholar 

Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Šestan N, Rakic P, Constantine-Paton M, Horvitz HR (2004) Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol 5(9):1–13

Article  Google Scholar 

Moon JM, Xu L, Giffard RG (2013) Inhibition of microRNA-181 reduces forebrain ischemia-induced neuronal loss. J Cereb Blood Flow Metab 33(12):1976–1982. https://doi.org/10.1038/jcbfm.2013.157

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ozcan M, Ayar A, Serhatlioglu I, Alcin E, Sahin Z, Kelestimur H (2010) Orexins activates protein kinase C-mediated Ca(2+) signaling in isolated rat primary sensory neurons. Physiol Res 59(2):255–262. https://doi.org/10.33549/physiolres.931739

Ozcan M, Gok ZB, Kacar E, Serhatlioglu I, Kelestimur H (2016) Nesfatin-1 increases intracellular calcium concentration by protein kinase C activation in cultured rat dorsal root ganglion neurons. Neurosci Lett 619:177–181. https://doi.org/10.1016/j.neulet.2016.03.018

Article  CAS  PubMed  Google Scholar 

Ozcan M, Canpolat S, Bulmus O, Ulker N, Tektemur A, Tekin S, Ozcan S, Serhatlioglu I, Kacar E, Ayar A, Kelestimur H (2019) Agomelatine pretreatment prevents development of hyperglycemia and hypoinsulinemia in streptozotocin-induced diabetes in mice. Fundam Clin Pharmacol 33(2):170–180. https://doi.org/10.1111/fcp.12413

Article  CAS  PubMed  Google Scholar 

Ozcan S, Kelestemur MM, Hekim MG, Bulmus O, Bulut F, Bilgin B, Canpolat S, Ozcan M (2022a) Asprosin, a novel therapeutic candidate for painful neuropathy: an experimental study in mice. Naunyn Schmiedebergs Arch Pharmacol 395(3):325–335. https://doi.org/10.1007/s00210-021-02197-w

Article  CAS  PubMed  Google Scholar 

Ozcan S, Ulker N, Bulmus O, Yardimci A, Ozcan M, Canpolat S (2022b) The modulatory effects of irisin on asprosin, leptin, glucose levels and lipid profile in healthy and obese male and female rats. Arch Physiol Biochem 128(3):724–731. https://doi.org/10.1080/13813455.2020.1722706

Article  CAS  PubMed  Google Scholar 

Pek SL, Sum CF, Lin MX, Cheng AK, Wong MT, Lim SC, Tavintharan S (2016) Circulating and visceral adipose miR-100 is down-regulated in patients with obesity and type 2 diabetes. Mol Cell Endocrinol 427:112–123. https://doi.org/10.1016/j.mce.2016.03.010

Article  CAS  PubMed  Google Scholar 

Peng L, Ma W, Yi F, Yang YJ, Lin W, Chen H, Zhang X, Zhang LH, Zhang F, Du Q (2014) MicroRNA profiling in Chinese patients with primary Sjögren syndrome reveals elevated miRNA-181a in peripheral blood mononuclear cells. J Rheumatol 41(11):2208–2213. https://doi.org/10.3899/jrheum.131154

Article  CAS  PubMed  Google Scholar 

Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H (2020) The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. PLoS Biol 18(7):e3000410. https://doi.org/10.1371/journal.pbio.3000410

Pope JE, Deer TR, Kramer J (2013) A systematic review: current and future directions of dorsal root ganglion therapeutics to treat chronic pain. Pain Med 14(10):1477–1496. https://doi.org/10.1111/pme.12171

Article  PubMed  Google Scholar 

Romere C, Duerrschmid C, Bournat J, Constable P, Jain M, Xia F, Saha PK, Del Solar M, Zhu B, York B, Sarkar P, Rendon DA, Gaber MW, LeMaire SA, Coselli JS, Milewicz DM, Sutton VR, Butte NF, Moore DD, Chopra AR (2016) Asprosin, a fasting-induced glucogenic protein hormone. Cell 165(3):566–579. https://doi.org/10.1016/j.cell.2016.02.063

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rother KI (2007) Diabetes treatment–bridging the divide. N Engl J Med 356(15):1499–1501. https://doi.org/10.1056/NEJMp078030

Article  CAS  PubMed  PubMed Central  Google Scholar 

Russell JW, Golovoy D, Vincent AM, Mahendru P, Olzmann JA, Mentzer A, Feldman EL (2002) High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 16:1738–1748. https://doi.org/10.1096/fj.01-1027com

Article  CAS  PubMed  Google Scholar 

Russell JW, Sullivan KA, Windebank AJ, Herrmann DN, Feldman EL (1999) Neurons undergo apoptosis in animal and cell culture models of diabetes. Neurobiol Dis 6(5):347–363. https://doi.org/10.1006/nbdi.1999.0254

Article  CAS  PubMed  Google Scholar 

Shi L, Cheng Z, Zhang J, Li R, Zhao P, Fu Z, You Y (2008) hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Res 1236:185–193. https://doi.org/10.1016/j.brainres.2008.07.085

Article  CAS  PubMed  Google Scholar 

Shi TJ, Zhang MD, Zeberg H, Nilsson J, Grünler J, Liu SX, Xiang Q, Persson J, Fried KJ, Catrina SB, Watanabe M, Arhem P, Brismar K, Hökfelt TG (2013) Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model. Proc Natl Acad Sci U S A 110(2):690–695. https://doi.org/10.1073/pnas.1220794110

Article  PubMed  Google Scholar 

Shillo P, Sloan G, Greig M, Hunt L, Selvarajah D, Elliott J, Gandhi R, Wilkinson ID, Tesfaye S (2019) Painful and painless diabetic neuropathies: what is the difference? Curr DiabRep 19(6):1–13

Google Scholar 

Shin D, Shin JY, McManus MT, Ptacek LJ, Fu YH (2009) Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann Neurol 66:843–857. https://doi.org/10.1002/ana.21927

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sui BD, Xu TQ, Liu JW, Wei W, Zheng CX, Guo BL, Wang YY, Yang YL (2013) Understanding the role of mitochondria in the pathogenesis of chronic pain. Postgrad Med J 89(1058):709–714. https://doi.org/10.1136/postgradmedj-2012-131068

Article  CAS  PubMed 

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