Unintended consequences: college students’ melatonin usage, sleep disturbance, and depressive symptoms

Nyer M, Farabaugh A, Fehling K, et al. Relationship between sleep disturbance and depression, anxiety, and functioning in college students. Depress Anxiety. 2013;30(9):873–80. https://doi.org/10.1002/da.22064.

Article  PubMed  Google Scholar 

Peltz JS, Bodenlos JS, Kingery JN, Rogge RD. The role of financial strain in college students’ work hours, sleep, and mental health. J Am Coll Health. 2020. https://doi.org/10.1080/07448481.2019.1705306.

Article  PubMed  Google Scholar 

Peltz JS, Rogge RD. The indirect effects of sleep hygiene and environmental factors on depressive symptoms in college students. Sleep Health. 2016;2(2):159–66. https://doi.org/10.1016/j.sleh.2016.01.007.

Article  PubMed  Google Scholar 

Doane LD, Gress-Smith JL, Breitenstein RS. Multi-method assessments of sleep over the transition to college and the associations with depression and anxiety symptoms. J Youth Adolesc. 2014;44(2):389–404. https://doi.org/10.1007/s10964-014-0150-7.

Article  PubMed  Google Scholar 

Cheng SH, Shih CC, Lee IH, et al. A study on the sleep quality of incoming university students. Psychiatry Res. 2012;197(3):270–4. https://doi.org/10.1016/j.psychres.2011.08.011.

Article  PubMed  Google Scholar 

Gaultney FJ. The prevalence of sleep disorders in college students: impact on academic performance. J Am Coll Health. 2010;59(2):91–7. https://doi.org/10.1080/07448481.2010.483708.

Article  PubMed  Google Scholar 

Hershner SD, Chervin RD. Causes and consequences of sleepiness among college students. Nat Sci Sleep. 2014;6:73–84. https://doi.org/10.2147/NSS.S62907.

Article  PubMed  PubMed Central  Google Scholar 

Tordjman S, Chokron S, Delorme R, et al. Melatonin: Pharmacology, functions and therapeutic benefits. Curr Neuropharmacol. 2017;15:434–43. https://doi.org/10.2174/1570159X14666161228122.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Palagini L, Manni R, Aguglia E, et al. International expert opinions and recommendations on the use of melatonin in the treatment of insomnia and circadian sleep disturbances in adult neuropsychiatric disorders. Front Psychiatry. 2021. https://doi.org/10.3389/fpsyt.2021.688890.

Article  PubMed  PubMed Central  Google Scholar 

Li J, Somers VK, Xu H, Lopez-Jimenez F, Covassin N. Trends in use of melatonin supplements among US adults, 1999–2018. JAMA. 2022;327(5):483–5. https://doi.org/10.1001/jama.2021.23652.

Article  PubMed  PubMed Central  Google Scholar 

Foley HM, Steel AE. Adverse events associated with oral administration of melatonin: A critical systematic review of clinical evidence. Complement Ther Med. 2019;42:65–81. https://doi.org/10.1016/j.ctim.2018.11.003.

Article  PubMed  Google Scholar 

Høier NK, Madsen T, Spira AP, et al. Associations between treatment with melatonin and suicidal behavior: a nationwide cohort study. J Clin Sleep Med. 2022;18(10):2451–8. https://doi.org/10.5664/jcsm.10118.

Article  PubMed  PubMed Central  Google Scholar 

Lund HG, Reider BD, Whiting AB, Prichard JR. Sleep patterns and predictors of disturbed sleep in a large population of college students. J Adolesc Health. 2010;46(2):124–32. https://doi.org/10.1016/j.jadohealth.2009.06.016.

Article  PubMed  Google Scholar 

Peltz JS, Rogge RD, Bodenlos JS, Kingery JN, Pigeon WR. Changes in psychological inflexibility as a potential mediator of longitudinal links between college students’ sleep problems and depressive symptoms. J Contextual Behav Sci. 2020. https://doi.org/10.1016/j.jcbs.2019.12.003.

Article  PubMed  PubMed Central  Google Scholar 

Ibrahim AK, Kelly SJ, Adams CE, Glazebrook C. A systematic review of studies of depression prevalence in university students. J Psychiatr Res. 2013;47(3):391–400. https://doi.org/10.1016/j.jpsychires.2012.11.015.

Article  PubMed  Google Scholar 

Bernert RA. Sleep disturbances and suicide risk: a review of the literature. Neuropsychiatr Dis Treat. 2008;3(6):735–43. https://doi.org/10.2147/ndt.s1248.

Article  Google Scholar 

Bernert RA, Nadorff MR. Sleep disturbances and suicide risk. Sleep Med Clin. 2015;10(1):35–9. https://doi.org/10.1016/j.jsmc.2014.11.004.

Article  PubMed  Google Scholar 

Fitzgerald CT, Messias E, Buysse DJ. Teen sleep and suicidality: results from the youth risk behavior surveys of 2007 and 2009. J Clin Sleep Med. 2011;7(4):351–6. https://doi.org/10.5664/JCSM.1188.

Article  PubMed  PubMed Central  Google Scholar 

Alvaro PK, Roberts RM, Harris JK. A systematic review assessing bidirectionality between sleep disturbances, anxiety, and depression. Sleep. 2013;36(7):1059–68. https://doi.org/10.5665/sleep.2810.

Article  PubMed  PubMed Central  Google Scholar 

Tavernier R, Willoughby T. Bidirectional associations between sleep (quality and duration) and psychosocial functioning across the university years. Dev Psychol. 2014;50(3):674–82. https://doi.org/10.1037/a0034258.

Article  PubMed  Google Scholar 

Menczel Schrire Z, Phillips CL, Chapman JL, et al. Safety of higher doses of melatonin in adults: a systematic review and meta-analysis. J Pineal Res. 2022. https://doi.org/10.1111/jpi.12782.

Article  PubMed  Google Scholar 

Andersen LPH, Gögenur I, Rosenberg J, Reiter RJ. The safety of melatonin in humans. Clin Drug Investig. 2016;36(3):169–75. https://doi.org/10.1007/s40261-015-0368-5.

Article  CAS  PubMed  Google Scholar 

Diaz S, Grigg-Damberger M. Eyes wide open: Sleep disturbance, not melatonin, is the real issue to address for suicide risk. J Clin Sleep Med. 2022;18(10):2337–8. https://doi.org/10.5664/jcsm.10118.

Article  PubMed  PubMed Central  Google Scholar 

Karin HA, Hössjer O, Bellocco R, Ye W, Trolle LY, Åkerstedt T. Insomnia in the context of short sleep increases suicide risk. Sleep. 2021. https://doi.org/10.1093/sleep/zsaa245.

Article  Google Scholar 

Perlis ML, Grandner MA, Chakravorty S, Bernert RA, Brown GK, Thase ME. Suicide and sleep: is it a bad thing to be awake when reason sleeps? Sleep Med Rev. 2016;29:101–7. https://doi.org/10.1016/j.smrv.2015.10.003.

Article  PubMed  Google Scholar 

Erland LAE, Saxena PK. Melatonin natural health products and supplements: presence of serotonin and significant variability of melatonin content. J Clin Sleep Med. 2017;13(2):275–81. https://doi.org/10.5664/jcsm.6462.

Article  PubMed  PubMed Central  Google Scholar 

Van Den Heuvel CJ, Ferguson SA, Mila MacChi M, Dawson D. Melatonin as a hypnotic: con. Sleep Med Rev. 2005;9(1):71–80. https://doi.org/10.1016/j.smrv.2004.07.001.

Article  PubMed  Google Scholar 

Yu L, Buysse DJ, Germain A, et al. Development of short forms from the PROMIS™ sleep disturbance and sleep-related impairment item banks. Behav Sleep Med. 2011;10(1):6–24. https://doi.org/10.1080/15402002.2012.636266.

Article  PubMed  PubMed Central  Google Scholar 

Kroenke K, Spitzer RL, Williams JBW. The Patient Health Questionnaire-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606–13. https://doi.org/10.1097/01.mlr.0000093487.78664.3c.

Article  CAS  PubMed  PubMed Central  Google Scholar 

American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. American Psychiatric Association; 2013.

Book  Google Scholar 

LeBourgeois MK, Giannotti F, Cortesi F, Wolfson AR, Harsh J. The relationship between reported sleep quality and sleep hygiene in Italian and American adolescents. Pediatrics. 2005;115(1 Suppl):257–65. https://doi.org/10.1542/peds.2004-0815H.

Article  PubMed  Google Scholar 

Hayes A. Introduction to mediation, moderation, and conditional process analysis: a regression-based approach. Guilford Press; 2017.

Google Scholar 

Alimoradi Z, Jafari E, Broström A, et al. Effects of cognitive behavioral therapy for insomnia (CBT-I) on quality of life: a systematic review and meta-analysis. Sleep Med Rev. 2022;64:1–15. https://doi.org/10.1016/j.smrv.2022.101646.

Article  Google Scholar 

留言 (0)

沒有登入
gif