Neuromodulation for Post-Stroke Motor Recovery: a Narrative Review of Invasive and Non‑Invasive Tools

Tsao CW, et al. Heart disease and stroke statistics—2023 update: a report from the American Heart Association. Circulation. 2023;147(8):e93–621.

Article  PubMed  Google Scholar 

Boyd LA, et al. Biomarkers of stroke recovery: consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable. Int J Stroke. 2017;12(5):480–93.

Article  PubMed  PubMed Central  Google Scholar 

Feng W, et al. Corticospinal tract lesion load: an imaging biomarker for stroke motor outcomes. Ann Neurol. 2015;78(6):860–70. This manuscript developed an imaging biomarker using a routine clinical MRI scan collected in the first 7 days, and it can effectively predict upper extremity impairment at 90 days. Lesion volume of 7.0cc is a critical threshold to have poor recovery in upper extremity.

Krakauer JW, Marshall RS. The proportional recovery rule for stroke revisited. Ann Neurol. 2015;78(6):845–7.

Article  CAS  PubMed  Google Scholar 

Keser Z, et al. Electroencephalogram (EEG) with or without transcranial magnetic stimulation (TMS) as biomarkers for post-stroke recovery: a narrative review. Front Neurol. 2022;13:827866.

Article  PubMed  PubMed Central  Google Scholar 

Nowak DA, et al. Interhemispheric competition after stroke: brain stimulation to enhance recovery of function of the affected hand. Neurorehabil Neural Repair. 2009;23(7):641–56.

Article  PubMed  Google Scholar 

Di Pino G, et al. Modulation of brain plasticity in stroke: a novel model for neurorehabilitation. Nat Rev Neurol. 2014;10(10):597–608.

Article  PubMed  Google Scholar 

Dromerick, A.W., et al. Critical Period After Stroke Study (CPASS): a phase II clinical trial testing an optimal time for motor recovery after stroke in humans. Proc Natl Acad Sci U S A 2021; 118(39)

Emara TH, et al. Repetitive transcranial magnetic stimulation at 1Hz and 5Hz produces sustained improvement in motor function and disability after ischaemic stroke. Eur J Neurol. 2010;17(9):1203–9.

Article  CAS  PubMed  Google Scholar 

Takeuchi N, et al. Inhibition of the unaffected motor cortex by 1 Hz repetitive transcranical magnetic stimulation enhances motor performance and training effect of the paretic hand in patients with chronic stroke. J Rehabil Med. 2008;40(4):298–303.

Article  PubMed  Google Scholar 

Harvey RL, et al. Randomized sham-controlled trial of navigated repetitive transcranial magnetic stimulation for motor recovery in stroke. Stroke. 2018;49(9):2138–46. The review paper proposed a bimodal balance-recovery model that links interhemispheric balancing and functional recovery to the structural reserve spared by the lesion.

Kim WS, et al. Low-frequency repetitive transcranial magnetic stimulation over contralesional motor cortex for motor recovery in subacute ischemic stroke: a randomized sham-controlled trial. Neurorehabil Neural Repair. 2020;34(9):856–67.

Article  PubMed  Google Scholar 

Lefaucheur JP, et al. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): an update (2014–2018). Clin Neurophysiol. 2020;131(2):474–528.

Article  PubMed  Google Scholar 

Vink JJT, et al. Continuous theta-burst stimulation of the contralesional primary motor cortex for promotion of upper limb recovery after stroke: a randomized controlled trial. Stroke. 2023;54(8):1962–71. This is single-center study demonstrated continuous theta burst stimulation of unaffected hemispheric can reduce motor impairment, improve function and enhance quality of life in a cohort of subacute stroke patients with upper extremity impairment.

Feng W, Plow EB, Paik NJ. Transcranial magnetic stimulation for poststroke motor recovery: what we have learned. Stroke. 2023;54(8):1972–3.

Article  PubMed  Google Scholar 

Chiu D, et al. Multifocal transcranial stimulation in chronic ischemic stroke: a phase 1/2a randomized trial. J Stroke Cerebrovasc Dis. 2020;29(6):104816.

Article  PubMed  Google Scholar 

Gholami M, Pourbaghi N, Taghvatalab S. Evaluation of rTMS in patients with poststroke aphasia: a systematic review and focused meta-analysis. Neurol Sci. 2022;43(8):4685–94.

Article  PubMed  Google Scholar 

Fu W, et al. Long-term effects of continuous theta-burst stimulation in visuospatial neglect. J Int Med Res. 2015;43(2):196–203.

Article  PubMed  Google Scholar 

Nyffeler T, et al. Theta burst stimulation in neglect after stroke: functional outcome and response variability origins. Brain. 2019;142(4):992–1008.

Article  PubMed  Google Scholar 

Cheng IKY, et al. Neuronavigated high-frequency repetitive transcranial magnetic stimulation for chronic post-stroke dysphagia: a randomized controlled study. J Rehabil Med. 2017;49(6):475–81.

Article  PubMed  Google Scholar 

Zhang C, et al. Repetitive transcranial magnetic stimulation in combination with neuromuscular electrical stimulation for treatment of post-stroke dysphagia. J Int Med Res. 2019;47(2):662–72.

Article  PubMed  Google Scholar 

Rossi C, et al. Transcranial direct current stimulation of the affected hemisphere does not accelerate recovery of acute stroke patients. Eur J Neurol. 2013;20(1):202–4.

Article  CAS  PubMed  Google Scholar 

Sattler V, et al. Anodal tDCS combined with radial nerve stimulation promotes hand motor recovery in the acute phase after ischemic stroke. Neurorehabil Neural Repair. 2015;29(8):743–54.

Article  PubMed  Google Scholar 

Hesse S, et al. Combined transcranial direct current stimulation and robot-assisted arm training in subacute stroke patients: an exploratory, randomized multicenter trial. Neurorehabil Neural Repair. 2011;25(9):838–46.

Article  PubMed  Google Scholar 

Khedr EM, et al. Effect of anodal versus cathodal transcranial direct current stimulation on stroke rehabilitation: a pilot randomized controlled trial. Neurorehabil Neural Repair. 2013;27(7):592–601.

Article  PubMed  Google Scholar 

Chang MC, Kim DY, Park DH. Enhancement of cortical excitability and lower limb motor function in patients with stroke by transcranial direct current stimulation. Brain Stimul. 2015;8(3):561–6.

Article  PubMed  Google Scholar 

Geroin C, et al. Combined transcranial direct current stimulation and robot-assisted gait training in patients with chronic stroke: a preliminary comparison. Clin Rehabil. 2011;25(6):537–48.

Article  PubMed  Google Scholar 

Viana RT, et al. Effects of the addition of transcranial direct current stimulation to virtual reality therapy after stroke: a pilot randomized controlled trial. NeuroRehabilitation. 2014;34(3):437–46.

Article  CAS  PubMed  Google Scholar 

Allman C, et al. Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke. Sci Transl Med. 2016;8(330):330re1.

Article  PubMed  PubMed Central  Google Scholar 

Vöröslakos M, et al. Direct effects of transcranial electric stimulation on brain circuits in rats and humans. Nat Commun. 2018;9(1):483.

Article  PubMed  PubMed Central  Google Scholar 

Marangolo P, et al. tDCS over the left inferior frontal cortex improves speech production in aphasia. Front Hum Neurosci. 2013;7:539.

Article  PubMed  PubMed Central  Google Scholar 

Campana S, Caltagirone C, Marangolo P. Combining voxel-based lesion-symptom mapping (VLSM) with A-tDCS language treatment: predicting outcome of recovery in nonfluent chronic aphasia. Brain Stimul. 2015;8(4):769–76.

Article  PubMed  Google Scholar 

Polanowska KE, et al. Anodal transcranial direct current stimulation in early rehabilitation of patients with post-stroke non-fluent aphasia: a randomized, double-blind, sham-controlled pilot study. Restor Neurol Neurosci. 2013;31(6):761–71.

PubMed  Google Scholar 

Keser Z, et al. Combined dextroamphetamine and transcranial direct current stimulation in poststroke aphasia. Am J Phys Med Rehabil. 2017;96(10):S141–5.

Article  PubMed  Google Scholar 

Keser Z, Francisco GE. Neuromodulation for post-stroke aphasia. Curr Phys Med Rehabil Rep. 2016;4(3):171–81.

Article  Google Scholar 

Fridriksson J, et al. Transcranial direct current stimulation vs sham stimulation to treat aphasia after stroke: a randomized clinical trial. JAMA Neurol. 2018;75(12):1470–6.

Article  PubMed  PubMed Central  Google Scholar 

Stockbridge MD, et al. Transcranial direct-current stimulation in subacute aphasia: a randomized controlled trial. Stroke. 2023;54(4):912–20.

Article  CAS  PubMed  Google Scholar 

Ko MH, et al. Home-based transcranial direct current stimulation to enhance cognition in stroke: randomized controlled trial. Stroke. 2022;53(10):2992–3001.

Article  CAS  PubMed  Google Scholar 

Bucak, B, Z. Keser. A commentary on: High-definition cathodal direct current stimulation for treatment of acute ischemic stroke: a randomized clinical trial. 2023 [cited 2023 07/15/2023]; Available from: https://www.practiceupdate.com/content/high-definition-cathodal-direct-current-stimulation-for-the-treatment-of-acute-ischemic-stroke/153641/65/7/1.

Pruvost-Robieux E, et al. Cathodal transcranial direct current stimulation in acute ischemic stroke: pilot randomized controlled trial. Stroke. 2021;52(6):1951–60.

Article  CAS  PubMed  Google Scholar 

Bahr-Hosseini M, et al. High-definition cathodal direct current stimulation for treatment of acute ischemic stroke: a randomized clinical trial. JAMA Netw Open. 2023;6(6):e2319231.

Article  PubMed  PubMed Central  Google Scholar 

Feng W, et al. Transcranial direct current stimulation for poststroke motor recovery: challenges and opportunities. PM R. 2018;10(9 Suppl 2):S157–64. This review paper summarized all of the challenges, barriers and opportunities for tDCS to be a viable neuromodulatory tool for stroke recovery.

Li, K.P., et al. Noninvasive brain stimulation for neurorehabilitation in post-stroke patients. Brain Sci 2023; 13(3)

Chaieb L, Antal A, Paulus W. Transcranial alternating current stimulation in the low kHz range increases motor cortex excitability. Restor Neurol Neurosci. 2011;29(3):167–75.

PubMed  Google Scholar 

Kanai R, Paulus W, Walsh V. Transcranial alternating current stimulation (tACS) modulates cortical excitability as assessed by TMS-induced phosphene thresholds. Clin Neurophysiol. 2010;121(9):1551–4.

Article  PubMed  Google Scholar 

Antal A, Paulu

留言 (0)

沒有登入
gif