A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes.
推出的年份: 2017
副标题
树号: D12.776.094.391, D12.776.947.125
MeSH 单一 ID: D000071192
进入的组:
Autophagy Related Protein 12
ATG12 Protein
Ubiquitin-Like Protein ATG12
ATG12, Ubiquitin-Like Protein
Ubiquitin Like Protein ATG12
早前的内容:
Small Ubiquitin-Related Modifier Proteins (2008-2016)
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