A ubiquitin-like protein that functions in CELL CYCLE regulation and embryogenesis. It is attached covalently to its substrates following activation by the UBIQUITIN-ACTIVATING ENZYME E1-UBA3 enzyme complex. NEDD8 attaches to CULLINS, activating their E3 UBIQUITIN LIGASE activity, to promote polyubiquitination and degradation of CYCLINS and regulatory proteins
推出的年份: 2018
副标题
树号: D12.776.947.218
MeSH 单一 ID: D000075687
进入的组:
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8
Neural Precursor Cell Expressed Developmentally Down Regulated Protein 8
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