A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
推出的年份: 2006(1993)
副标题
树号: D12.776.930.608
MeSH 单一 ID: D050778
进入的组:
Transcription Factors, NFATC
Transcription Factor NF-AT
NF-AT, Transcription Factor
Transcription Factor NF AT
Nuclear Factor of Activated T-Cells, Cytoplasmic
Nuclear Factor of Activated T Cells, Cytoplasmic
NFAT Proteins
NFATC Proteins
Nuclear Factors of Activated T-Cells
Nuclear Factors of Activated T Cells
NF-AT Proteins
NF AT Proteins
NFAT Transcription Factor 4
NFATC3 Transcription Factor
Factor, NFATC3 Transcription
Transcription Factor, NFATC3
NFATx Protein
Nuclear Factor of Activated T-Cells, Cytoplasmic 3 Protein
Nuclear Factor of Activated T Cells, Cytoplasmic 3 Protein
NF-AT4 Protein
NF AT4 Protein
NFAT4 Protein
NFATC3 Protein
NFAT Transcription Factor 2
NFAT-2 Protein
NFAT 2 Protein
Nuclear Factor of Activated T-Cells, Cytoplasmic 1 Protein
Nuclear Factor of Activated T Cells, Cytoplasmic 1 Protein
NFATC1 Protein
NFATC1 Transcription Factor
Factor, NFATC1 Transcription
Transcription Factor, NFATC1
NF-ATc1 Protein
NF ATc1 Protein
NFAT2 Protein
NFAT Transcription Factor 3
NFATC4 Transcription Factor
Transcription Factor, NFATC4
NFAT3 Protein
NFATC4 Protein
Nuclear Factor of Activated T-Cells, Cytoplasmic 4 Protein
Nuclear Factor of Activated T Cells, Cytoplasmic 4 Protein
NF-AT3 Protein
NF AT3 Protein
NFAT Transcription Factor 5
Nuclear Factor of Activated T-Cells 5 Protein
Nuclear Factor of Activated T Cells 5 Protein
OREBP Protein
Osmotic Response Element Binding Protein
NFATL1 Protein
Tonicity-Responsive Enhancer-Binding Protein
Tonicity Responsive Enhancer Binding Protein
NFAT5 Protein
NFATz Protein
TonEBP Protein
NFAT Transcription Factor 1
NFATC2 Transcription Factor
Factor, NFATC2 Transcription
Transcription Factor, NFATC2
NFAT1 Protein
NFATC2 Protein
Nuclear Factor of Activated T-Cells, Cytoplasmic 2 Protein
Nuclear Factor of Activated T Cells, Cytoplasmic 2 Protein
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