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Duocarmycins
A group of pyrroloindole compounds often with additional spirocyclic unit(s) and their analogs originally isolated from STREPTOMYCES. They bind DNA minor grooves with adenine-N3 alkylation activity.
推出的年份: 2020
副标题
administration and dosage
adverse effects
agonists
analogs and derivatives
antagonists and inhibitors
blood
cerebrospinal fluid
chemical synthesis
chemistry
classification
economics
history
immunology
isolation and purification
metabolism
pharmacokinetics
pharmacology
poisoning
radiation effects
standards
supply and distribution
therapeutic use
toxicity
urine
树号:
D03.383.129.578.275, D03.633.100.473.278
MeSH 单一 ID:
D000080890
进入的组:
Duocarmycin
早前的内容:
Indoles (1988-2019)
Pyrroles (1988-2019)
药理作用*:
Antibiotics, Antineoplastic
Antineoplastic Agents, Alkylating
All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Pyrroles [D03.383.129.578]
Atorvastatin [D03.383.129.578.075]
Cromakalim [D03.383.129.578.150]
Duocarmycins [D03.383.129.578.275]
Maleimides [D03.383.129.578.399]
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Porphobilinogen [D03.383.129.578.617]
Prodigiosin [D03.383.129.578.748]
Pyrrolnitrin [D03.383.129.578.770]
Ryanodine [D03.383.129.578.805]
Sunitinib [D03.383.129.578.823]
Tetrapyrroles [D03.383.129.578.840]
add_circle
Tolmetin [D03.383.129.578.910]
All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Adrenochrome [D03.633.100.473.025]
Alcian Blue [D03.633.100.473.050]
Carbazoles [D03.633.100.473.144]
add_circle
Cytochalasins [D03.633.100.473.231]
add_circle
Delavirdine [D03.633.100.473.250]
Duocarmycins [D03.633.100.473.278]
Fluvastatin [D03.633.100.473.305]
Gliotoxin [D03.633.100.473.360]
Hydroxytryptophol [D03.633.100.473.385]
Ibogaine [D03.633.100.473.390]
Indapamide [D03.633.100.473.391]
Indican [D03.633.100.473.393]
Indigo Carmine [D03.633.100.473.396]
Indocyanine Green [D03.633.100.473.400]
Indole Alkaloids [D03.633.100.473.402]
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Indoleacetic Acids [D03.633.100.473.404]
add_circle
Indolequinones [D03.633.100.473.412]
add_circle
Indomethacin [D03.633.100.473.420]
add_circle
Indoramin [D03.633.100.473.432]
Iprindole [D03.633.100.473.469]
Isatin [D03.633.100.473.525]
Methisazone [D03.633.100.473.615]
Molindone [D03.633.100.473.629]
Oxyphenisatin Acetate [D03.633.100.473.725]
Panobinostat [D03.633.100.473.746]
Perindopril [D03.633.100.473.766]
Skatole [D03.633.100.473.808]
Sporidesmins [D03.633.100.473.840]
Sunitinib [D03.633.100.473.877]
Tropisetron [D03.633.100.473.896]
Tryptamines [D03.633.100.473.914]
add_circle
Vemurafenib [D03.633.100.473.936]
Vilazodone Hydrochloride [D03.633.100.473.957]
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